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ChemicalBook >> CAS DataBase List >> LOFEPRAMINE

LOFEPRAMINE

LOFEPRAMINE price.
  • $32 - $1208
  • Product name: LOFEPRAMINE
  • CAS: 23047-25-8
  • MF: C26H27ClN2O
  • MW: 418.96
  • EINECS:245-396-8
  • MDL Number:MFCD00865465
  • Synonyms:LOFEPRAMINE;Gamanil;1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]ethanone;4'-Chloro-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl-methylamino]acetophenone;Amplit;Leo 640;Lopramine;1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz(Z)[b,f]azepin-5-yl)propyl]methylamino]ethanone
54 prices
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  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
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  • Manufactureraablocks
  • Product numberAA002LXG
  • Product description1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 99%
  • Packaging50mg
  • Price$115
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002LXG
  • Product description1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 99%
  • Packaging100mg
  • Price$138
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002LXG
  • Product description1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 95%
  • Packaging250mg
  • Price$324
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002LXG
  • Product description1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 99%
  • Packaging10mg
  • Price$46
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002LXG
  • Product description1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 99%
  • Packaging5mg
  • Price$38
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002LXG
  • Product description1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one ≥95%
  • Packaging1mg
  • Price$36
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002LXG
  • Product description1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 95%
  • Packaging1g
  • Price$1208
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberZ238316
  • Product descriptionLofepramine 98%
  • Packaging25MG
  • Price$110
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238316
  • Product descriptionLofepramine 98%
  • Packaging100MG
  • Price$235
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberE443
  • Product descriptionLofepramine
  • Packaging10mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberE443
  • Product descriptionLofepramine
  • Packaging50mg
  • Price$560
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003200
  • Product descriptionLOFEPRAMINE 95.00%
  • Packaging10MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003200
  • Product descriptionLOFEPRAMINE 95.00%
  • Packaging5MG
  • Price$338.8
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB7097
  • Product descriptionLofepramine
  • Packaging10mg
  • Price$219
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB7097
  • Product descriptionLofepramine
  • Packaging50mg
  • Price$501
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7097
  • Product descriptionLofepramine
  • Packaging10mg
  • Price$149
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002LXG 1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 99% 50mg $115 2026-05-28 Buy
aablocks AA002LXG 1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 99% 100mg $138 2026-05-28 Buy
aablocks AA002LXG 1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 95% 250mg $324 2026-05-28 Buy
aablocks AA002LXG 1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 99% 10mg $46 2026-05-28 Buy
aablocks AA002LXG 1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 99% 5mg $38 2026-05-28 Buy
aablocks AA002LXG 1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one ≥95% 1mg $36 2026-05-28 Buy
aablocks AA002LXG 1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one 95% 1g $1208 2026-05-28 Buy
ACHEMBLOCK Z238316 Lofepramine 98% 25MG $110 2026-05-27 Buy
ACHEMBLOCK Z238316 Lofepramine 98% 100MG $235 2026-05-27 Buy
AK Scientific E443 Lofepramine 10mg $195 2021-12-16 Buy
AK Scientific E443 Lofepramine 50mg $560 2021-12-16 Buy
American Custom Chemicals Corporation API0003200 LOFEPRAMINE 95.00% 10MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation API0003200 LOFEPRAMINE 95.00% 5MG $338.8 2021-12-16 Buy
ApexBio Technology B7097 Lofepramine 10mg $219 2021-12-16 Buy
ApexBio Technology B7097 Lofepramine 50mg $501 2026-05-06 Buy
ApexBio Technology B7097 Lofepramine 10mg $149 2026-05-06 Buy

Properties

Melting point :103-105°C
vapor pressure :0Pa at 25℃
storage temp. :Store at +4°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :Light Yellow to Light Beige
Water Solubility :2.04mg/L at 25℃
Stability :Unstable in Solution

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

Description

Lofepramine is a first generation tricyclic antidepressant that is extensively metabolized to desipramine. It potently inhibits serotonin and norepinephrine transporters (Kds = 70 and 5.4 nM, respectively) and less potently antagonizes serotonin, histamine, and muscarinic receptors.

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