LUMIRACOXIB
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- $28 - $1000
- Product name: LUMIRACOXIB
- CAS: 220991-20-8
- MF: C15H13ClFNO2
- MW: 293.72
- EINECS:1308068-626-2
- MDL Number:MFCD07186254
- Synonyms:2-[2-[(2-chloro-6-fluoro-phenyl)amino]-5-methyl-phenyl]acetic acid;2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetic Acid;CGS 35189;COX 189;Prexige;Lumaricoxib;Benzeneacetic acid, 2-((2-chloro-6-fluorophenyl)amino)-5-methyl-;Unii-V91T9204hu
39 prices
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Brand
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth
- Cayman Chemical
- Crysdot
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 10mg
- 50MG
- EvaluationSample
- 1unit
- 50.00mg
- 100.00mg
- 100MG
- 0.1g
- 250mg
- 250.00mg
- 1g
- ManufacturerACHEMBLOCK
- Product numberAD265261
- Product descriptionLumiracoxib 98%
- Packaging50MG
- Price$115
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD265261
- Product descriptionLumiracoxib 98%
- Packaging100MG
- Price$185
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberR809
- Product descriptionLumiracoxib
- Packaging50mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberR809
- Product descriptionLumiracoxib
- Packaging250mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112255
- Product description2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98%
- Packaging250mg
- Price$294
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112255
- Product description2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98%
- Packaging100mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112255
- Product description2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98%
- Packaging50mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112255
- Product description2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98%
- Packaging10mg
- Price$47
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112255
- Product description2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98%
- Packaging1g
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003229
- Product descriptionLUMIRACOXIB 95.00%
- Packaging10MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1458
- Product descriptionLumiracoxib
- Packaging250mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1458
- Product descriptionLumiracoxib
- Packaging250mg
- Price$189
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1458
- Product descriptionLumiracoxib
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1458
- Product descriptionLumiracoxib
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1458
- Product descriptionLumiracoxib
- Packaging100mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1458
- Product descriptionLumiracoxib
- Packaging100mg
- Price$119
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | AD265261 | Lumiracoxib 98% | 50MG | $115 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD265261 | Lumiracoxib 98% | 100MG | $185 | 2026-05-27 | Buy |
| AK Scientific | R809 | Lumiracoxib | 50mg | $140 | 2021-12-16 | Buy |
| AK Scientific | R809 | Lumiracoxib | 250mg | $410 | 2021-12-16 | Buy |
| Ambeed | A112255 | 2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98% | 250mg | $294 | 2021-12-16 | Buy |
| Ambeed | A112255 | 2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98% | 100mg | $137 | 2021-12-16 | Buy |
| Ambeed | A112255 | 2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98% | 50mg | $75 | 2021-12-16 | Buy |
| Ambeed | A112255 | 2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98% | 10mg | $47 | 2021-12-16 | Buy |
| Ambeed | A112255 | 2-(2-((2-Chloro-6-fluorophenyl)amino)-5-methylphenyl)aceticacid 98% | 1g | $1000 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003229 | LUMIRACOXIB 95.00% | 10MG | $704.55 | 2021-12-16 | Buy |
| ApexBio Technology | B1458 | Lumiracoxib | 250mg | $189 | 2021-12-16 | Buy |
| ApexBio Technology | B1458 | Lumiracoxib | 250mg | $189 | 2026-05-06 | Buy |
| ApexBio Technology | B1458 | Lumiracoxib | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | B1458 | Lumiracoxib | EvaluationSample | $30 | 2026-05-06 | Buy |
| ApexBio Technology | B1458 | Lumiracoxib | 100mg | $119 | 2021-12-16 | Buy |
| ApexBio Technology | B1458 | Lumiracoxib | 100mg | $119 | 2026-05-06 | Buy |
Properties
Melting point :139-141°C
Boiling point :395.7±42.0 °C(Predicted)
Density :1.363±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≥29.4 mg/mL in DMSO; insoluble in H2O; ≥27.15 mg/mL in EtOH with ultrasonic
form :solid
pka :4.18±0.10(Predicted)
color :White to light yellow
InChI :1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20)
InChIKey :KHPKQFYUPIUARC-UHFFFAOYSA-N
SMILES :ClC1=CC=CC(F)=C1NC2=CC=C(C)C=C2CC(O)=O
CAS DataBase Reference :220991-20-8
Boiling point :395.7±42.0 °C(Predicted)
Density :1.363±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≥29.4 mg/mL in DMSO; insoluble in H2O; ≥27.15 mg/mL in EtOH with ultrasonic
form :solid
pka :4.18±0.10(Predicted)
color :White to light yellow
InChI :1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20)
InChIKey :KHPKQFYUPIUARC-UHFFFAOYSA-N
SMILES :ClC1=CC=CC(F)=C1NC2=CC=C(C)C=C2CC(O)=O
CAS DataBase Reference :220991-20-8
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
As a second-generation, selective cyclooxygenase (COX-2) inhibitor, lumiracoxib is devoid of the gastrointestinal issues that plague other non-selective, nonsteroidal, anti-inflammatory drugs (NSAIDs) that crossover to COX-1. As an inhibitor of the inducible COX-2 that is up-regulated in pathological processes of pain and inflammation, lumiracoxib blocks the conversion of arachidonic acid to prostaglandins, the mediators of the pathological effects. It’s mode of binding to COX-2 has been found to differ from the other selective COX-2 inhibitors; the carboxylic acid forms hydrogen bonds with Tyr-385 and Ser-530 in the catalytic site rather than seeking interactions within the larger hydrophobic side pocket. Since lumiracoxib is mainly metabolized by CYP2C9, a study evaluating the co-administration of lumiracoxib with fluconazole, a potent inhibitor of CYP2C9, was conducted, and it concluded that there was no need for lumiracoxib dose adjustment, since changes in the systemic exposure were not significant. No serious adverse effects were reported, but in the small number of cases where treatment was discontinued, Gastro intestinal (GI) and musculoskeletal complaints were common.More related product prices
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