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ChemicalBook >> CAS DataBase List >> Mevastatin

Mevastatin

$5 - $1593.9
Product name: Mevastatin
CAS: 73573-88-3
MF: C23H34O5
MW: 390.51
EINECS:700-442-0
MDL Number:MFCD05662341
Synonyms:Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-;,8-beta(2s*,4s*),8a-beta))- ;antibioticml236b ;butanoicacid,2-methyl-,1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hy ;compactin(penicillium) ;(S)-2-Methylbutyric acid [(1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]naphthalen-1-yl] ester;2-Methyl-butanoic acid [1S-[1-α(R*),7-β,8-β(2S*,4S*),8a-β]]-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester;Mevastatin, >=97%

Price106 Properties Safety Information Description

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aablocks
Adipogen Life Sciences
AHH
AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Biosynth
Cayman Chemical
Chemenu
Chem-Impex
ChemScene
Crysdot
CSNpharm
DC Chemicals
Medical Isotopes, Inc.
Sigma-Aldrich
TCI Chemical
Thermo Scientific Chemicals
Tocris
TRC
Usbiological

Package

5mg
20mg
25mg
100mg
2g
500mg
10mM(in 1mL DMSO)
50
10
10g
10mg
50mg
250mg
0.5g
1g
5g
100g
500g
25g
10mM(in1mLDMSO)

Manufactureraablocks
Product numberAA0038E1
Product description(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 95%
Packaging10mg
Price$8
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038E1
Product description(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate ≥96%(HPLC)
Packaging250mg
Price$10
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038E1
Product description(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 95%
Packaging50mg
Price$10
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038E1
Product description(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 97%
Packaging1g
Price$11
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038E1
Product description(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 97%
Packaging5g
Price$12
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038E1
Product description(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 95%
Packaging25g
Price$32
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038E1
Product description(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 95%
Packaging100g
Price$91
Updated2026-05-28
Buy

ManufacturerAdipogen Life Sciences
Product numberCDX-M0183-M050
Product descriptionMevastatin ≥95%(NMR)
Packaging50mg
Price$63
Updated2026-05-06
Buy

ManufacturerAHH
Product numberAPI-1661
Product descriptionMevastatin 98%
Packaging0.5g
Price$370
Updated2021-12-16
Buy

ManufacturerAHH
Product numberAPI-1661
Product descriptionMevastatin 97%
Packaging0.5g
Price$370
Updated2026-05-26
Buy

ManufacturerAK Scientific
Product numberI518
Product descriptionMevastatin
Packaging1g
Price$111
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberI518
Product descriptionMevastatin
Packaging250mg
Price$63
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA445160
Product descriptionMevastatin 95%
Packaging25g
Price$40
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA445160
Product descriptionMevastatin 95%
Packaging25g
Price$40
Updated2026-06-05
Buy

ManufacturerAmbeed
Product numberA445160
Product descriptionMevastatin 95%
Packaging50mg
Price$12
Updated2026-06-05
Buy

ManufacturerAmbeed
Product numberA445160
Product descriptionMevastatin 95%
Packaging5g
Price$15
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA0038E1	(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 95%	10mg	$8	2026-05-28	Buy
aablocks	AA0038E1	(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate ≥96%(HPLC)	250mg	$10	2026-05-28	Buy
aablocks	AA0038E1	(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 95%	50mg	$10	2026-05-28	Buy
aablocks	AA0038E1	(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 97%	1g	$11	2026-05-28	Buy
aablocks	AA0038E1	(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 97%	5g	$12	2026-05-28	Buy
aablocks	AA0038E1	(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 95%	25g	$32	2026-05-28	Buy
aablocks	AA0038E1	(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate 95%	100g	$91	2026-05-28	Buy
Adipogen Life Sciences	CDX-M0183-M050	Mevastatin ≥95%(NMR)	50mg	$63	2026-05-06	Buy
AHH	API-1661	Mevastatin 98%	0.5g	$370	2021-12-16	Buy
AHH	API-1661	Mevastatin 97%	0.5g	$370	2026-05-26	Buy
AK Scientific	I518	Mevastatin	1g	$111	2021-12-16	Buy
AK Scientific	I518	Mevastatin	250mg	$63	2021-12-16	Buy
Ambeed	A445160	Mevastatin 95%	25g	$40	2021-12-16	Buy
Ambeed	A445160	Mevastatin 95%	25g	$40	2026-06-05	Buy
Ambeed	A445160	Mevastatin 95%	50mg	$12	2026-06-05	Buy
Ambeed	A445160	Mevastatin 95%	5g	$15	2021-12-16	Buy

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Properties

Melting point :151-153 °C
alpha :D22 +283° (c = 0.48 in acetone)
Boiling point :555.0±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
vapor pressure :0Pa at 25℃
storage temp. :2-8°C
solubility :DMSO: 20 mg/mL
pka :13.49±0.40(Predicted)
form :powder
color :white
λmax :246nm(MeOH)(lit.)
Merck :14,6164
BRN :1269441
InChIKey :AJLFOPYRIVGYMJ-INTXDZFKSA-N
SMILES :[H][C@]12[C@H](CCC=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)[C@@H](C)CC
CAS DataBase Reference :73573-88-3(CAS DataBase Reference)

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.

Description

Mevastatin (Compactin) inhibits HMGCR (HMG-CoA reductase) , induces apoptosis which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases.

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Suppliers and manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

$10.00
Mevastatin CAS:73573-88-3

Hangzhou ICH Biofarm Co., Ltd

Mevastatin CAS:73573-88-3

Shandong Xuhuang New material CoLTD

$30.00
Mevastatin CAS:73573-88-3

HubeiwidelychemicaltechnologyCo.,Ltd

$1.00
mevastatin CAS:73573-88-3

Beijing Cooperate Pharmaceutical Co.,Ltd

Henan Tianfu Chemical Co.,Ltd.

Shanghai Zheyan Biotech Co., Ltd.

Xiamen AmoyChem Co., Ltd

Standardpharm Co. Ltd.

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Mevastatin

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Description

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