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ChemicalBook >> CAS DataBase List >> N-Ethylmaleimide

N-Ethylmaleimide

N-Ethylmaleimide price.
  • $5 - $1451
  • Product name: N-Ethylmaleimide
  • CAS: 128-53-0
  • MF: C6H7NO2
  • MW: 125.13
  • EINECS:204-892-4
  • MDL Number:MFCD00005509
  • Synonyms:usafb-121 ;N-ETHYLMALEIMIDE;1-Ethyl-1H-pyrrole-2,5-dione~NEM;N-ETHYLMALEIMIDE SIGMAULTRA;N-ETHYLMALEIMIDE 99+%;N-EthylmaleimideA.R.;N-Ethylmaleimide-D5;1-ETHYLPYRROLE-2,5-DIONE
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  • Manufactureraablocks
  • Product numberAA000XL4
  • Product descriptionN-Ethylmaleimide 97%
  • Packaging5g
  • Price$19
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000XL4
  • Product descriptionN-Ethylmaleimide 98%
  • Packaging10g
  • Price$31
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000XL4
  • Product descriptionN-Ethylmaleimide 98%
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  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000XL4
  • Product descriptionN-Ethylmaleimide 98%
  • Packaging50g
  • Price$115
  • Updated2026-05-25
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  • Product numberAA000XL4
  • Product descriptionN-Ethylmaleimide 98%
  • Packaging25g
  • Price$61
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000XL4
  • Product descriptionN-Ethylmaleimide 98%
  • Packaging100g
  • Price$216
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberW170612
  • Product descriptionN-Ethylmaleimide 97%
  • Packaging100G
  • Price$185
  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberMT-12502
  • Product descriptionN-Ethylmaleimide 98%
  • Packaging5g
  • Price$488
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-12502
  • Product descriptionN-Ethylmaleimide 97%
  • Packaging5g
  • Price$488
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberMT-12502
  • Product descriptionN-Ethylmaleimide 97%
  • Packaging5g
  • Price$488
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product number7671AF
  • Product descriptionN-Ethylmaleimide
  • Packaging5g
  • Price$67
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA175883
  • Product description1-Ethyl-1H-pyrrole-2,5-dione 97+%
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  • Price$36
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA175883
  • Product description1-Ethyl-1H-pyrrole-2,5-dione 97+%
  • Packaging25g
  • Price$121
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA175883
  • Product description1-Ethyl-1H-pyrrole-2,5-dione 97+%
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  • Price$11
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  • ManufacturerAmbeed
  • Product numberA175883
  • Product description1-Ethyl-1H-pyrrole-2,5-dione 97+%
  • Packaging100g
  • Price$406
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC6454
  • Product descriptionN-Ethylmaleimide (NEM)
  • Packaging25mg
  • Price$56
  • Updated2026-05-06
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000XL4 N-Ethylmaleimide 97% 5g $19 2026-05-25 Buy
aablocks AA000XL4 N-Ethylmaleimide 98% 10g $31 2026-05-25 Buy
aablocks AA000XL4 N-Ethylmaleimide 98% 1g $7 2026-05-25 Buy
aablocks AA000XL4 N-Ethylmaleimide 98% 50g $115 2026-05-25 Buy
aablocks AA000XL4 N-Ethylmaleimide 98% 25g $61 2026-05-25 Buy
aablocks AA000XL4 N-Ethylmaleimide 98% 100g $216 2026-05-25 Buy
ACHEMBLOCK W170612 N-Ethylmaleimide 97% 100G $185 2026-05-27 Buy
AHH MT-12502 N-Ethylmaleimide 98% 5g $488 2021-12-16 Buy
AHH MT-12502 N-Ethylmaleimide 97% 5g $488 2026-05-25 Buy
AHH MT-12502 N-Ethylmaleimide 97% 5g $488 2026-05-26 Buy
AK Scientific 7671AF N-Ethylmaleimide 5g $67 2021-12-16 Buy
Ambeed A175883 1-Ethyl-1H-pyrrole-2,5-dione 97+% 5g $36 2021-12-16 Buy
Ambeed A175883 1-Ethyl-1H-pyrrole-2,5-dione 97+% 25g $121 2021-12-16 Buy
Ambeed A175883 1-Ethyl-1H-pyrrole-2,5-dione 97+% 1g $11 2021-12-16 Buy
Ambeed A175883 1-Ethyl-1H-pyrrole-2,5-dione 97+% 100g $406 2021-12-16 Buy
ApexBio Technology C6454 N-Ethylmaleimide (NEM) 25mg $56 2026-05-06 Buy

Properties

Melting point :43-46 °C(lit.)
Boiling point :210 °C(lit.)
Density :1.2500 (rough estimate)
refractive index :1.4430 (estimate)
Flash point :73 °C
storage temp. :2-8°C
solubility :methanol: 1 M at 20 °C, clear, colorless
form :Crystalline Powder
pka :-2.18±0.20(Predicted)
color :White to off-white
biological source :synthetic (organic)
Water Solubility :1 g/L (20 ºC)
Sensitive :Light Sensitive
Merck :14,3822
BRN :112448
Stability :Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate.
InChI :1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
InChIKey :HDFGOPSGAURCEO-UHFFFAOYSA-N
SMILES :CCN1C(=O)C=CC1=O || CCN1C(=O)C=CC1=O
CAS DataBase Reference :128-53-0(CAS DataBase Reference)
NIST Chemistry Reference :1H-pyrrole-2,5-dione, 1-ethyl-(128-53-0)
EPA Substance Registry System :N-Ethylmaleimide (128-53-0)
Absorption :cut-off at 382nm in methanol at 1M

Safety Information

Symbol(GHS): Corrosion (GHS05)Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Description

N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg dependent internucleosomal DNA fragmentation.

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