NU 2058
|
- $12 - $2455.22
- Product name: NU 2058
- CAS: 161058-83-9
- MF: C12H17N5O
- MW: 247.3
- EINECS:
- MDL Number:MFCD05664734
- Synonyms:6-(Cyclohexylmethoxy)-9H-purin-2-amine;2-aMino-6-purine;2-aMino-6-[(cyclohexylMethyl)oxy]purine;2-Amino-6-(cyclohexylmethoxy)purine;CS-2601;NU 2058;NU-2058;NU2058;NU-2058;O6-(CYCLOHEXYLMETHYL)GUANINE;NU2058>
72 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mL(10mMinDMSO)
- 20mg
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 50.00g
- 100.00g
- 100G
- 250.00g
- Manufactureraablocks
- Product numberAA001VIT
- Product descriptionNU2058 99%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001VIT
- Product descriptionNU2058 99%
- Packaging5mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001VIT
- Product descriptionNU2058 99%
- Packaging10mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001VIT
- Product descriptionNU2058 99%
- Packaging25mg
- Price$34
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001VIT
- Product descriptionNU2058 99%
- Packaging50mg
- Price$46
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001VIT
- Product descriptionNU2058 99%
- Packaging100mg
- Price$64
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001VIT
- Product descriptionNU2058 ≥98%
- Packaging1g
- Price$560
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number0515CA
- Product description6-O-Cyclohexylmethylguanine
- Packaging1g
- Price$456
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0515CA
- Product description6-O-Cyclohexylmethylguanine
- Packaging100mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA168683
- Product descriptionNU 2058 98+%
- Packaging100mg
- Price$152
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA168683
- Product descriptionNU 2058 98+%
- Packaging25mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA168683
- Product descriptionNU 2058 98+%
- Packaging50mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA168683
- Product descriptionNU 2058 98+%
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA168683
- Product descriptionNU 2058 98+%
- Packaging5mg
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA168683
- Product descriptionNU 2058 98+%
- Packaging1g
- Price$1292
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001281
- Product descriptionNU 2058 95.00%
- Packaging100G
- Price$2455.22
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001VIT | NU2058 99% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA001VIT | NU2058 99% | 5mg | $17 | 2026-05-28 | Buy |
| aablocks | AA001VIT | NU2058 99% | 10mg | $27 | 2026-05-28 | Buy |
| aablocks | AA001VIT | NU2058 99% | 25mg | $34 | 2026-05-28 | Buy |
| aablocks | AA001VIT | NU2058 99% | 50mg | $46 | 2026-05-28 | Buy |
| aablocks | AA001VIT | NU2058 99% | 100mg | $64 | 2026-05-28 | Buy |
| aablocks | AA001VIT | NU2058 ≥98% | 1g | $560 | 2026-05-28 | Buy |
| AK Scientific | 0515CA | 6-O-Cyclohexylmethylguanine | 1g | $456 | 2021-12-16 | Buy |
| AK Scientific | 0515CA | 6-O-Cyclohexylmethylguanine | 100mg | $138 | 2021-12-16 | Buy |
| Ambeed | A168683 | NU 2058 98+% | 100mg | $152 | 2021-12-16 | Buy |
| Ambeed | A168683 | NU 2058 98+% | 25mg | $90 | 2021-12-16 | Buy |
| Ambeed | A168683 | NU 2058 98+% | 50mg | $117 | 2021-12-16 | Buy |
| Ambeed | A168683 | NU 2058 98+% | 10mg | $70 | 2021-12-16 | Buy |
| Ambeed | A168683 | NU 2058 98+% | 5mg | $54 | 2021-12-16 | Buy |
| Ambeed | A168683 | NU 2058 98+% | 1g | $1292 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001281 | NU 2058 95.00% | 100G | $2455.22 | 2021-12-16 | Buy |
Properties
Melting point :199°C(lit.)
Boiling point :424.8±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: 22 mg/mL
form :powder to crystal
pka :7.36±0.20(Predicted)
color :white
λmax :281nm(MeOH)(lit.)
InChI :InChI=1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17)
InChIKey :MWGXGTJJAOZBNW-UHFFFAOYSA-N
SMILES :N1C2C(=NC(N)=NC=2OCC2CCCCC2)NC=1
Boiling point :424.8±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: 22 mg/mL
form :powder to crystal
pka :7.36±0.20(Predicted)
color :white
λmax :281nm(MeOH)(lit.)
InChI :InChI=1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17)
InChIKey :MWGXGTJJAOZBNW-UHFFFAOYSA-N
SMILES :N1C2C(=NC(N)=NC=2OCC2CCCCC2)NC=1
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
NU2058, O(6)-Cyclohexylmethylguanine, has displayed the capacity to competitively inhibit CDK1 and CDK2 with respect to ATP and has also been shown to inhibit Topo II ATPase activity. Studies suggest that NU2058 also modifies p53-dependent transcription and interrupts the cell cycle causing cell growth arrest. NU2058 demonstrates the ability to alter the transport of platinum-based compounds via an increase in DNA adducts, which causes an increase in intracellular platinum levels. Further experiments reveal that growth inhibition caused by NU2058 is correlated to an increase in p27 levels, a decrease in early gene expression and CDK2 activity, as well as G1 cell cycle arrest. NU2058 is an inhibitor of cyclin A and cyclin B.More related product prices
773-64-8 PD0332991 Isethionate ROSCOVITINE OTAVA-BB 1115529 471270-60-7 Flavopiridol PROSTAGLANDIN A2 BUTYROLACTONE I BML-259 6-MethoxyguanineRelated product price
-
773-64-8
$5-4225.87 -
PD0332991 Isethionate
$16-2220 -
ROSCOVITINE
$19-2245.7
