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ChemicalBook >> CAS DataBase List >> Nimesulide

Nimesulide

Nimesulide price.
  • $5 - $5058.9
  • Product name: Nimesulide
  • CAS: 51803-78-2
  • MF: C13H12N2O5S
  • MW: 308.31
  • EINECS:257-431-4
  • MDL Number:MFCD00079470
  • Synonyms:nimed ;4-NITRO-2-PHENOXYMETHANE SULPHONANILIDE;CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE IMP. E (EP):(RS)-2-[2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHOXY]ETHOXY]ACETIC ACID MM(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD);4-Nitro-2-phenoxymethanesulfonamide;Nide;Nidol
70 prices
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  • aablocks
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
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  • Biosynth
  • Cayman Chemical
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  • Sigma-Aldrich
  • TCI Chemical
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Package
  • 10mM(in1mLDMSO)
  • EvaluationSample
  • 10mM(in 1mL DMSO)
  • 5MG
  • 100mg
  • 1mg
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  • y0001237
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  • Manufactureraablocks
  • Product numberAA00I96M
  • Product descriptionNimesulide 98%
  • Packaging1mg
  • Price$8
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I96M
  • Product descriptionNimesulide 98%
  • Packaging25mg
  • Price$10
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I96M
  • Product descriptionNimesulide ≥98%(HPLC)
  • Packaging1g
  • Price$11
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I96M
  • Product descriptionNimesulide 98%
  • Packaging5g
  • Price$18
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I96M
  • Product descriptionNimesulide ≥98%(HPLC)
  • Packaging25g
  • Price$61
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I96M
  • Product descriptionNimesulide ≥98%(HPLC)
  • Packaging100g
  • Price$195
  • Updated2026-05-29
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  • ManufacturerAHH
  • Product numberMT-57002
  • Product descriptionNimesulide 99%
  • Packaging250g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-57002
  • Product descriptionNimesulide 97%
  • Packaging250g
  • Price$400
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-57002
  • Product descriptionNimesulide 97%
  • Packaging250g
  • Price$400
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11497
  • Product descriptionNimesulide
  • Packaging25mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ50241
  • Product descriptionNimesulide
  • Packaging5g
  • Price$35
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging10g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging25g
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging5g
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I96M Nimesulide 98% 1mg $8 2026-05-29 Buy
aablocks AA00I96M Nimesulide 98% 25mg $10 2026-05-29 Buy
aablocks AA00I96M Nimesulide ≥98%(HPLC) 1g $11 2026-05-29 Buy
aablocks AA00I96M Nimesulide 98% 5g $18 2026-05-29 Buy
aablocks AA00I96M Nimesulide ≥98%(HPLC) 25g $61 2026-05-29 Buy
aablocks AA00I96M Nimesulide ≥98%(HPLC) 100g $195 2026-05-29 Buy
AHH MT-57002 Nimesulide 99% 250g $400 2021-12-16 Buy
AHH MT-57002 Nimesulide 97% 250g $400 2026-05-25 Buy
AHH MT-57002 Nimesulide 97% 250g $400 2026-05-26 Buy
AK Scientific J11497 Nimesulide 25mg $29 2021-12-16 Buy
AK Scientific J50241 Nimesulide 5g $35 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 10g $39 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 25g $59 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 5g $22 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 1g $11 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 25mg $5 2021-12-16 Buy

Properties

Melting point :140-146°C
Boiling point :442.0±55.0 °C(Predicted)
Density :1.451±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in acetone, slightly soluble in anhydrous ethanol.
form :Solid
pka :pKa 6.56± 0.03(H2O,t =25,I=0.02)(Approximate)
color :Light orange to Yellow to Green
biological source :synthetic (organic)
Water Solubility :Soluble in water (<50 &#181;g/ml), 1:10 DMSO:PBS (pH 7.2) (<200 &#181;g/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.
λmax :391nm(H2O)(lit.)
Merck :14,6548
Stability :Stable. Incompatible with strong oxidizing agents.
Major Application :pharmaceutical (small molecule)
InChI :1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
InChIKey :HYWYRSMBCFDLJT-UHFFFAOYSA-N
SMILES :CS(NC1=C(OC2=CC=CC=C2)C=C([N+]([O-])=O)C=C1)(=O)=O
CAS DataBase Reference :51803-78-2(CAS DataBase Reference)
EPA Substance Registry System :Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)- (51803-78-2)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. It is indicated for the treatment of acute pain, symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults. However, due to the risk of causing hepatotoxicity, it should not be taken long-term. It has also been withdrawn from the markets in many countries. It mechanism of action is through targeting on various key mediators in the inflammatory process such as COX-2 mediated prostaglandins, free radicals, proteolytic enzymes and histamine.

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