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ChemicalBook >> CAS DataBase List >> O-Desmethylvenlafaxine

O-Desmethylvenlafaxine

O-Desmethylvenlafaxine price.
  • $5 - $1440
  • Product name: O-Desmethylvenlafaxine
  • CAS: 93413-62-8
  • MF: C16H25NO2
  • MW: 263.38
  • EINECS:700-516-2
  • MDL Number:MFCD00871934
  • Synonyms:O-DESMETHYL VENLAFAXINE-D10;DL-O-Desmethylvenlafaxin;4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol;O-Desmethylvenlafaxine;Desvenlafaxine(O-Desnethylvenfaxine);1-[1-(4-Hydroxyphenyl)-2-dimethylaminoethyl]cyclohexanol;4-[1-(1-Hydroxycyclohexyl)-2-(dimethylamino)ethyl]phenol;Desmethylvenlafaxine
88 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
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  • Cayman Chemical
  • Chem-Impex
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  • Medical Isotopes, Inc.
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Package
  • 1mg
  • 250mg
  • 10mM*1mLinDMSO(Solution)
  • 100μg
  • 50mg
  • 0.5g
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 500mg
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  • 10mM(in 1mL DMSO)
  • 10mM(in1mLDMSO)
  • 5x1mL
  • 100mg
  • EvaluationSample
  • Manufactureraablocks
  • Product numberAA006FVB
  • Product description4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 98%
  • Packaging100g
  • Price$1096
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006FVB
  • Product description4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 98%
  • Packaging25g
  • Price$340
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006FVB
  • Product description4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 98%
  • Packaging5g
  • Price$96
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006FVB
  • Product description4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 98%
  • Packaging1g
  • Price$35
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006FVB
  • Product description4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol >98%(HPLC)powder
  • Packaging5mg
  • Price$25
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238319
  • Product descriptionDesvenlafaxine 98%
  • Packaging25G
  • Price$585
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238319
  • Product descriptionDesvenlafaxine 98%
  • Packaging5G
  • Price$135
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10126
  • Product descriptionO-Desmethylvenlafaxine >98%(HPLC),powder
  • Packaging5mg
  • Price$22
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ94960
  • Product descriptionDesvenlafaxine 95%
  • Packaging1g
  • Price$27
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberX4688
  • Product descriptionDesvenlafaxine 98%(GC)
  • Packaging5g
  • Price$107
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10126
  • Product descriptionO-Desmethylvenlafaxine >98%(HPLC),powder
  • Packaging100mg
  • Price$79
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10126
  • Product descriptionO-Desmethylvenlafaxine >98%(HPLC),powder
  • Packaging25mg
  • Price$40
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberX4688
  • Product descriptionDesvenlafaxine 98%(GC)
  • Packaging1g
  • Price$37
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10126
  • Product descriptionO-Desmethylvenlafaxine
  • Packaging100mg
  • Price$195
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberX4688
  • Product descriptionDesvenlafaxine 98%(GC)
  • Packaging25g
  • Price$399
  • Updated2026-06-04
  • Buy
  • ManufacturerAmbeed
  • Product numberA105155
  • Product descriptionDesvenlafaxine 98+%
  • Packaging100g
  • Price$821
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA006FVB 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 98% 100g $1096 2026-05-28 Buy
aablocks AA006FVB 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 98% 25g $340 2026-05-28 Buy
aablocks AA006FVB 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 98% 5g $96 2026-05-28 Buy
aablocks AA006FVB 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 98% 1g $35 2026-05-28 Buy
aablocks AA006FVB 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol >98%(HPLC)powder 5mg $25 2026-05-28 Buy
ACHEMBLOCK Z238319 Desvenlafaxine 98% 25G $585 2026-05-27 Buy
ACHEMBLOCK Z238319 Desvenlafaxine 98% 5G $135 2026-05-27 Buy
AK Scientific J10126 O-Desmethylvenlafaxine >98%(HPLC),powder 5mg $22 2026-06-04 Buy
AK Scientific J94960 Desvenlafaxine 95% 1g $27 2026-06-04 Buy
AK Scientific X4688 Desvenlafaxine 98%(GC) 5g $107 2026-06-04 Buy
AK Scientific J10126 O-Desmethylvenlafaxine >98%(HPLC),powder 100mg $79 2026-06-04 Buy
AK Scientific J10126 O-Desmethylvenlafaxine >98%(HPLC),powder 25mg $40 2026-06-04 Buy
AK Scientific X4688 Desvenlafaxine 98%(GC) 1g $37 2026-06-04 Buy
AK Scientific J10126 O-Desmethylvenlafaxine 100mg $195 2021-12-16 Buy
AK Scientific X4688 Desvenlafaxine 98%(GC) 25g $399 2026-06-04 Buy
Ambeed A105155 Desvenlafaxine 98+% 100g $821 2021-12-16 Buy

Properties

Melting point :208-213°C
Boiling point :403.8±25.0 °C(Predicted)
Density :1.115±0.06 g/cm3(Predicted)
Flash point :9℃
storage temp. :2-8°C
solubility :insoluble in EtOH; ≥13.2 mg/mL in DMSO; ≥2.45 mg/mL in EtOH
form :Solid
pka :10.04±0.26(Predicted)
color :White to off-white
Major Application :clinical testing
InChI :1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3
InChIKey :KYYIDSXMWOZKMP-UHFFFAOYSA-N
SMILES :N(CC(C2(CCCCC2)O)c1ccc(cc1)O)(C)C
LogP :0.33 at 25℃ and pH6

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Desvenlafaxine is a new member of the SNRI class of antidepressants. It is marketed as an extended release tablet for once-daily oral treatment of MDD in adult patients. Desvenlafaxine (O-desmethylvenlafaxine) is the major active metabolite of the previously marketed antidepressant venlafaxine (Effexor). Similar to venlafaxine, desvenlafaxine is a more potent inhibitor of serotonin and norepinephrine reuptake (IC50=47 and 531 nM, respectively) than that of dopamine (62% inhibition at 100 mM) in in vitro studies. It does not have significant in vitro affinity for other neurotransmitter reporters such as a1-adrenergic, H1-histaminergic, or muscarine-cholinergic receptors. Desvenlafaxine is marketed as a racemic mixture. Specific pharmacological properties of the enantiomers of desvenlafaxine have not been reported.

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