OTAVA-BB 7070707015
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- $14 - $2841
- Product name: OTAVA-BB 7070707015
- CAS: 934593-90-5
- MF: C26H29NO5
- MW: 435.51
- EINECS:
- MDL Number:MFCD09907563
- Synonyms:OTAVA-BB 7070707015;CAY10585;HIF-1α inhibitor;LW8;4-Hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7]dec-1-ylphenoxy)acetyl]aMino]-benzoic Acid Methyl Ester;Hypoxia inducible factor-1α inhibitor;CAY 10585;CAY-10585;CAY10585;LW6;LW 6 (This product is unavailable in the U.S.)
83 prices
Selected condition：
Brand
- aablocks
- Abosyn
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10
- 10mg
- 10mM*1mLinDMSO(Solution)
- 25mg
- 50mg
- 0.1g
- 100mg
- 0.25g
- 250mg
- 0.5g
- 10mM(1mLinDMSO)
- 1G
- 10 mg
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00GT7U
- Product descriptionMethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97%
- Packaging1mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT7U
- Product descriptionMethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97%
- Packaging5mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT7U
- Product descriptionMethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97%
- Packaging10mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT7U
- Product descriptionMethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97%
- Packaging25mg
- Price$58
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT7U
- Product descriptionMethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97%
- Packaging50mg
- Price$98
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT7U
- Product descriptionMethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97%
- Packaging100mg
- Price$165
- Updated2026-05-28
- Buy
- ManufacturerAbosyn
- Product number90-2799
- Product descriptionmethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate >95%(Puritymayvarybetweenbatches)
- Packaging0.1g
- Price$99
- Updated2026-05-21
- Buy
- ManufacturerAbosyn
- Product number90-2799
- Product descriptionmethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate >95%(Puritymayvarybetweenbatches)
- Packaging0.25g
- Price$195
- Updated2026-05-21
- Buy
- ManufacturerAbosyn
- Product number90-2799
- Product descriptionmethyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate >95%(Puritymayvarybetweenbatches)
- Packaging0.5g
- Price$295
- Updated2026-05-21
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65765
- Product descriptionmethyl 3-(2-(4-((1R,3R,5R,7R)-adamantan-2-yl)phenoxy)acetamido)-4-hydroxybenzoate 98%
- Packaging25MG
- Price$175
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65765
- Product descriptionmethyl 3-(2-(4-((1R,3R,5R,7R)-adamantan-2-yl)phenoxy)acetamido)-4-hydroxybenzoate 98%
- Packaging100MG
- Price$425
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65765
- Product descriptionmethyl 3-(2-(4-((1R,3R,5R,7R)-adamantan-2-yl)phenoxy)acetamido)-4-hydroxybenzoate 98%
- Packaging1G
- Price$1650
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65765
- Product descriptionmethyl 3-(2-(4-((1R,3R,5R,7R)-adamantan-2-yl)phenoxy)acetamido)-4-hydroxybenzoate 98%
- Packaging5MG
- Price$55
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1793AH
- Product descriptionHypoxiainduciblefactor-1Ainhibitor
- Packaging5mg
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121335
- Product descriptionLW6 97%
- Packaging25mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA121335
- Product descriptionLW6 97%
- Packaging10mg
- Price$63
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GT7U | Methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97% | 1mg | $14 | 2026-05-28 | Buy |
| aablocks | AA00GT7U | Methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97% | 5mg | $27 | 2026-05-28 | Buy |
| aablocks | AA00GT7U | Methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97% | 10mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00GT7U | Methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97% | 25mg | $58 | 2026-05-28 | Buy |
| aablocks | AA00GT7U | Methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97% | 50mg | $98 | 2026-05-28 | Buy |
| aablocks | AA00GT7U | Methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate 97% | 100mg | $165 | 2026-05-28 | Buy |
| Abosyn | 90-2799 | methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate >95%(Puritymayvarybetweenbatches) | 0.1g | $99 | 2026-05-21 | Buy |
| Abosyn | 90-2799 | methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate >95%(Puritymayvarybetweenbatches) | 0.25g | $195 | 2026-05-21 | Buy |
| Abosyn | 90-2799 | methyl 3-(2-(4-(adamantan-1-yl)phenoxy)acetamido)-4-hydroxybenzoate >95%(Puritymayvarybetweenbatches) | 0.5g | $295 | 2026-05-21 | Buy |
| ACHEMBLOCK | Q65765 | methyl 3-(2-(4-((1R,3R,5R,7R)-adamantan-2-yl)phenoxy)acetamido)-4-hydroxybenzoate 98% | 25MG | $175 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65765 | methyl 3-(2-(4-((1R,3R,5R,7R)-adamantan-2-yl)phenoxy)acetamido)-4-hydroxybenzoate 98% | 100MG | $425 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65765 | methyl 3-(2-(4-((1R,3R,5R,7R)-adamantan-2-yl)phenoxy)acetamido)-4-hydroxybenzoate 98% | 1G | $1650 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65765 | methyl 3-(2-(4-((1R,3R,5R,7R)-adamantan-2-yl)phenoxy)acetamido)-4-hydroxybenzoate 98% | 5MG | $55 | 2026-05-27 | Buy |
| AK Scientific | 1793AH | Hypoxiainduciblefactor-1Ainhibitor | 5mg | $167 | 2021-12-16 | Buy |
| Ambeed | A121335 | LW6 97% | 25mg | $147 | 2021-12-16 | Buy |
| Ambeed | A121335 | LW6 97% | 10mg | $63 | 2021-12-16 | Buy |
Properties
Boiling point :647.4±55.0 °C(Predicted)
Density :1.295±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:17.5(Max Conc. mg/mL);40.18(Max Conc. mM)
DMF:25.6(Max Conc. mg/mL);58.8(Max Conc. mM) pka :7.59±0.48(Predicted)
form :powder to crystal
color :White to Light yellow to Light orange
InChI :1S/C26H29NO5/c1-31-25(30)19-2-7-23(28)22(11-19)27-24(29)15-32-21-5-3-20(4-6-21)26-12-16-8-17(13-26)10-18(9-16)14-26/h2-7,11,16-18,28H,8-10,12-15H2,1H3,(H,27,29)
InChIKey :BJRPPNOJYFZSLY-UHFFFAOYSA-N
SMILES :N(c5c(ccc(c5)C(=O)OC)O)C(=O)COc1ccc(cc1)C32CC4CC(C3)CC(C2)C4
Density :1.295±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:17.5(Max Conc. mg/mL);40.18(Max Conc. mM)
DMF:25.6(Max Conc. mg/mL);58.8(Max Conc. mM) pka :7.59±0.48(Predicted)
form :powder to crystal
color :White to Light yellow to Light orange
InChI :1S/C26H29NO5/c1-31-25(30)19-2-7-23(28)22(11-19)27-24(29)15-32-21-5-3-20(4-6-21)26-12-16-8-17(13-26)10-18(9-16)14-26/h2-7,11,16-18,28H,8-10,12-15H2,1H3,(H,27,29)
InChIKey :BJRPPNOJYFZSLY-UHFFFAOYSA-N
SMILES :N(c5c(ccc(c5)C(=O)OC)O)C(=O)COc1ccc(cc1)C32CC4CC(C3)CC(C2)C4
Safety Information
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Description
Hypoxia Inducible Factor-1α Inhibitor is a novel small molecule which inhibits HIF by reducing HIF-1α accumulation and gene transcriptional activity. In a gene reporter assay using human AGS and Hep3B cell lines, hypoxia inducible factor-1α Inhibitor prevented HIF-1 transcriptional activity with IC50 values of 2.6 and 0.7 μM, respectively. Hypoxia inducible factor-1α inhibitor blocks HIF-1α accumulation in Hep3B cells in a concentration and time-dependent manner, with complete inhibition at a concentration of 30 μM within 12 hours. Hypoxia inducible factor-1α inhibitor also significantly suppresses transcription of the HIF-1 target genes VEGF and erythropoietin at 10 μM.More related product prices
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