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ChemicalBook >> CAS DataBase List >> Olodaterol

Olodaterol

Olodaterol price.
  • $56 - $1700
  • Product name: Olodaterol
  • CAS: 868049-49-4
  • MF: C21H26N2O5
  • MW: 386.44
  • EINECS:813-858-3
  • MDL Number:MFCD16619349
  • Synonyms:6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one;2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-;BI 1744(Olodaterol;Striverdi Respimat);Olodaterol;Olodaterol ImpurityA  ;BI-1744;Striverdi
32 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 2mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4736BB
  • Product descriptionOlodaterol
  • Packaging2mg
  • Price$171
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0014046
  • Product descriptionOLODATEROL 95.00%
  • Packaging5MG
  • Price$501.28
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1223805
  • Product descriptionOlodaterol >98%(HPLC)
  • Packaging10mg
  • Price$510
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1223805
  • Product descriptionOlodaterol >98%(HPLC)
  • Packaging25mg
  • Price$980
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb2276859
  • Product descriptionOlodaterol 98.90%(Mayvarybetweenbatches)
  • Packaging1mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1223805
  • Product descriptionOlodaterol >98%(HPLC)
  • Packaging2mg
  • Price$210
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb2276859
  • Product descriptionOlodaterol 98.90%(Mayvarybetweenbatches)
  • Packaging5mg
  • Price$240
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1223805
  • Product descriptionOlodaterol >98%(HPLC)
  • Packaging5mg
  • Price$350
  • Updated2026-05-06
  • Buy
  • ManufacturerBiosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging25mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging2mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging1mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21794
  • Product descriptionOlodaterol ≥98%
  • Packaging1mg
  • Price$89
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21794
  • Product descriptionOlodaterol ≥98%
  • Packaging1mg
  • Price$98
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number21794
  • Product descriptionOlodaterol ≥98%
  • Packaging5mg
  • Price$289
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4736BB Olodaterol 2mg $171 2021-12-16 Buy
American Custom Chemicals Corporation API0014046 OLODATEROL 95.00% 5MG $501.28 2021-12-16 Buy
Biorbyt Ltd orb1223805 Olodaterol >98%(HPLC) 10mg $510 2026-05-06 Buy
Biorbyt Ltd orb1223805 Olodaterol >98%(HPLC) 25mg $980 2026-05-06 Buy
Biorbyt Ltd orb2276859 Olodaterol 98.90%(Mayvarybetweenbatches) 1mg $90 2026-05-06 Buy
Biorbyt Ltd orb1223805 Olodaterol >98%(HPLC) 2mg $210 2026-05-06 Buy
Biorbyt Ltd orb2276859 Olodaterol 98.90%(Mayvarybetweenbatches) 5mg $240 2026-05-06 Buy
Biorbyt Ltd orb1223805 Olodaterol >98%(HPLC) 5mg $350 2026-05-06 Buy
Biosynth FH152793 Olodaterol 25mg $325 2021-12-16 Buy
Biosynth FH152793 Olodaterol 10mg $250 2021-12-16 Buy
Biosynth FH152793 Olodaterol 2mg $90 2021-12-16 Buy
Biosynth FH152793 Olodaterol 1mg $56 2021-12-16 Buy
Biosynth FH152793 Olodaterol 5mg $160 2021-12-16 Buy
Cayman Chemical 21794 Olodaterol ≥98% 1mg $89 2024-03-01 Buy
Cayman Chemical 21794 Olodaterol ≥98% 1mg $98 2026-04-30 Buy
Cayman Chemical 21794 Olodaterol ≥98% 5mg $289 2024-03-01 Buy

Properties

Boiling point :649.0±55.0 °C(Predicted)
Density :1.250
solubility :DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :9.42±0.20(Predicted)
color :Light yellow to khaki
Stability :Hygroscopic

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314 Get medical advice/attention if you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

In 2013, olodaterol (also known BI-1744 CL) was approved for the treatment of chronic obstructive pulmonary disease (COPD) in Russia (March), Canada (June), and the EuropeanUnion (October). Olodaterol is delivered via the Respimat Soft Mist inhaler. Olodaterol was discovered from an effort to identify a β2-adrenergic receptor agonist that could be given once daily and with a superior safety profile over known β2- adrenergic receptor agonists. Olodaterol is a potent β2 agonist (EC50=0.1 nM, intrinsic activity=88%) and is highly selective for the β2 receptor over β1 and β3 receptors. In preclinical models in guinea pigs and dogs, olodaterol had a rapid onset of action and provided bronchoprotection over 24 h. Mechanistic studies indicated that olodaterol forms a highly stable complex with the β2-adrenergic receptor, with a dissociation half-life of 17.8 h. The synthesis of olodaterol proceeds through an (R)-styrene epoxide that is prepared via enantioselective reduction of an α-chloroketone intermediate. Ring opening of the epoxide with 1-(4- methoxyphenyl)-2-methylpropan-2-amine provides olodaterol.

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