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ChemicalBook >> CAS DataBase List >> PFI-1

PFI-1

$12 - $2691.1
Product name: PFI-1
CAS: 1403764-72-6
MF: C16H17N3O4S
MW: 347.39
EINECS:
MDL Number:MFCD22580416
Synonyms:PFI-1;PFI-1 (PF-6405761);PFI-1 (PF-06405761);PF-06405761;Benzenesulfonamide, 2-methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)-;2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide PFI-1 (PF-6405761);2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydro-quinazolin-6-yl)-bezenesulfonamide;PFI-1;PFI-1;PFI 1;PFI1

Price84 Properties Safety Information Description

84 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
BroadPharm
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

10mM*1mLinDMSO
100.00mg
50.00mg
10mM*1mLinDMSO(Solution)
50
200mg
10
250.00mg
10mM*1mLinDMSO(Solid+Solvent)
1mg
5mg
10mg
25MG
50mg
100mg
250mg
1G

Manufactureraablocks
Product numberAA009CBG
Product description2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%
Packaging5mg
Price$23
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CBG
Product description2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%
Packaging10mg
Price$32
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CBG
Product description2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%
Packaging1mg
Price$12
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CBG
Product description2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%
Packaging50mg
Price$80
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CBG
Product description2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%
Packaging100mg
Price$122
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CBG
Product description2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%
Packaging250mg
Price$207
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product number10245
Product descriptionPFI-1 98%
Packaging100MG
Price$275
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product number10245
Product descriptionPFI-1 98%
Packaging1G
Price$870
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product number10245
Product descriptionPFI-1 98%
Packaging25MG
Price$105
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product numberSYN3009
Product descriptionPF-06405761
Packaging10mg
Price$175
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA280183
Product description2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%
Packaging50mg
Price$185
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA280183
Product description2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%
Packaging100mg
Price$260
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA280183
Product description2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%
Packaging250mg
Price$545
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA280183
Product description2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%
Packaging1mg
Price$23
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA280183
Product description2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%
Packaging5mg
Price$47
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA280183
Product description2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%
Packaging10mg
Price$67
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA009CBG	2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%	5mg	$23	2026-05-28	Buy
aablocks	AA009CBG	2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%	10mg	$32	2026-05-28	Buy
aablocks	AA009CBG	2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%	1mg	$12	2026-05-28	Buy
aablocks	AA009CBG	2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%	50mg	$80	2026-05-28	Buy
aablocks	AA009CBG	2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%	100mg	$122	2026-05-28	Buy
aablocks	AA009CBG	2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-yl)Benzenesulfonamide 98%	250mg	$207	2026-05-28	Buy
ACHEMBLOCK	10245	PFI-1 98%	100MG	$275	2026-05-27	Buy
ACHEMBLOCK	10245	PFI-1 98%	1G	$870	2026-05-27	Buy
ACHEMBLOCK	10245	PFI-1 98%	25MG	$105	2026-05-27	Buy
AK Scientific	SYN3009	PF-06405761	10mg	$175	2021-12-16	Buy
Ambeed	A280183	2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%	50mg	$185	2021-12-16	Buy
Ambeed	A280183	2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%	100mg	$260	2021-12-16	Buy
Ambeed	A280183	2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%	250mg	$545	2021-12-16	Buy
Ambeed	A280183	2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%	1mg	$23	2021-12-16	Buy
Ambeed	A280183	2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%	5mg	$47	2021-12-16	Buy
Ambeed	A280183	2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 98+%	10mg	$67	2021-12-16	Buy

Next Last

Properties

storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to beige
InChI :1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20)
InChIKey :TXZPMHLMPKIUGK-UHFFFAOYSA-N
SMILES :COc1ccccc1S(=O)(=O)Nc2ccc3NC(=O)N(C)Cc3c2

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Bromodomains recognize acetylated lysine residues and recruit regulatory complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. The isolated individual or tandem bromodomains of bromodomain-containing protein (BRD) 2 and BRD4 bind acetylated histone tails, which couples histone acetylation marks to the transcriptional regulation of target promoters. Small molecule inhibitors of bromodomain interactions hold promise as useful therapeutics for human disease. PFI-1 is a BET bromodomain inhibitor that exhibits inhibitory activity at BRD2 and BRD4. In an AlphaScreen assay it has been shown to inhibit BRD2 bromodomain 2 and BRD4 bromodomain 1 with IC50 values of 98 nM and 0.22 μM, respectively. See the Structural Genomics Consortium (SGC) website for more information.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

$70.00
PFI-1 CAS:1403764-72-6

Henan Aochuang Chemical Co.,Ltd.

PFI-1 CAS:1403764-72-6

ATK CHEMICAL COMPANY LIMITED

Changzhou PBpharmaceutical R&D Co.,Ltd

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Dideu Industries Group Limited

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

HANGZHOU LEAP CHEM CO., LTD.

TargetMol Chemicals Inc.

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PFI-1

Properties

Safety Information

Description

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