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ChemicalBook >> CAS DataBase List >> Phlorizin

Phlorizin

Phlorizin price.
  • $8 - $1587.5
  • Product name: Phlorizin
  • CAS: 60-81-1
  • MF: C21H24O10
  • MW: 436.41
  • EINECS:200-487-1
  • MDL Number:MFCD00006591
  • Synonyms:1-propanone,1-(2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyp ;phlorizoside ;1-Propanone, 1-[2-(β-D-glucopyranosyloxy)-;4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-;Floridzin;1-(2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)-propan-1-on;phlorrhizin ;TIMTEC-BB SBB005924
120 prices
Selected condition:
Brand
  • aablocks
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • JR MediChem
  • Labseeker
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5MG
  • 10mM*1mLinDMSO(Solution)
  • 10mg
  • 20mg
  • 25mg
  • 200mg
  • 250mg
  • 1mlx10mM(inDMSO)
  • 50mg
  • 100mg
  • 10mM(in1mLDMSO)
  • 500mg
  • 1g
  • 1000mg
  • 10mM(in 1mL DMSO)
  • 2g
  • 2.5g
  • 5g
  • 10g
  • 20g
  • 25g
  • 100g
  • 250g
  • 1kg
  • Manufactureraablocks
  • Product numberAA00IAKC
  • Product descriptionPhloridzin 98%
  • Packaging250mg
  • Price$8
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IAKC
  • Product descriptionPhloridzin 98%
  • Packaging1g
  • Price$10
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IAKC
  • Product descriptionPhloridzin 98%
  • Packaging5g
  • Price$18
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IAKC
  • Product descriptionPhloridzin 98%
  • Packaging25g
  • Price$44
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IAKC
  • Product descriptionPhloridzin 98%
  • Packaging10g
  • Price$34
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IAKC
  • Product descriptionPhloridzin ≥98%(HPLC)
  • Packaging250g
  • Price$321
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IAKC
  • Product descriptionPhloridzin ≥98%(HPLC)
  • Packaging1kg
  • Price$1007
  • Updated2026-05-29
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-P0263-M250
  • Product descriptionPhloridzin ≥98%(HPLC)
  • Packaging250mg
  • Price$40
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-P0263-G001
  • Product descriptionPhloridzin ≥98%(HPLC)
  • Packaging1g
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-P0263-G001
  • Product descriptionPhloridzin ≥98%(HPLC)
  • Packaging1g
  • Price$66
  • Updated2026-05-06
  • Buy
  • ManufacturerAHH
  • Product numberMT-57943
  • Product descriptionPhloridzin 98%
  • Packaging20g
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-57943
  • Product descriptionPhloridzin 97%
  • Packaging20g
  • Price$350
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-57943
  • Product descriptionPhloridzin 97%
  • Packaging20g
  • Price$350
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ438
  • Product descriptionPhloridzin 98%(HPLC)
  • Packaging25g
  • Price$118
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ438
  • Product descriptionPhloridzin 98%(HPLC)
  • Packaging100g
  • Price$354
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ438
  • Product descriptionPhloridzin
  • Packaging100g
  • Price$343
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00IAKC Phloridzin 98% 250mg $8 2026-05-29 Buy
aablocks AA00IAKC Phloridzin 98% 1g $10 2026-05-29 Buy
aablocks AA00IAKC Phloridzin 98% 5g $18 2026-05-29 Buy
aablocks AA00IAKC Phloridzin 98% 25g $44 2026-05-29 Buy
aablocks AA00IAKC Phloridzin 98% 10g $34 2026-05-29 Buy
aablocks AA00IAKC Phloridzin ≥98%(HPLC) 250g $321 2026-05-29 Buy
aablocks AA00IAKC Phloridzin ≥98%(HPLC) 1kg $1007 2026-05-29 Buy
Adipogen Life Sciences CDX-P0263-M250 Phloridzin ≥98%(HPLC) 250mg $40 2026-05-06 Buy
Adipogen Life Sciences CDX-P0263-G001 Phloridzin ≥98%(HPLC) 1g $59 2021-12-16 Buy
Adipogen Life Sciences CDX-P0263-G001 Phloridzin ≥98%(HPLC) 1g $66 2026-05-06 Buy
AHH MT-57943 Phloridzin 98% 20g $350 2021-12-16 Buy
AHH MT-57943 Phloridzin 97% 20g $350 2026-05-25 Buy
AHH MT-57943 Phloridzin 97% 20g $350 2026-05-26 Buy
AK Scientific Q438 Phloridzin 98%(HPLC) 25g $118 2026-06-04 Buy
AK Scientific Q438 Phloridzin 98%(HPLC) 100g $354 2026-06-04 Buy
AK Scientific Q438 Phloridzin 100g $343 2021-12-16 Buy

Properties

Melting point :113-114 °C(lit.)
Boiling point :468.89°C (rough estimate)
Density :1.3178 (rough estimate)
refractive index :-54 ° (C=3.2, 95% EtOH)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.15±0.40(Predicted)
color :Light Yellow to Tan
Merck :14,7327
Major Application :food and beverages
Cosmetics Ingredients Functions :SKIN CONDITIONING
InChIKey :IOUVKUPGCMBWBT-LKLLPNDVNA-N
SMILES :C(C1C(=CC(O)=CC=1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O)(=O)CCC1C=CC(O)=CC=1 |&1:9,10,11,13,15,r|
LogP :0.452 (est)
CAS DataBase Reference :60-81-1(CAS DataBase Reference)
EPA Substance Registry System :Phlorizin (60-81-1)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sodium-glucose cotransporter 1 (SGLT1) is a high affinity, low capacity transporter abundant in the small intestine, with some expression in the kidney as well. SGLT2 is a low affinity, high capacity transporter in the kidney that accounts for approximately 90% of glucose reabsorption into the blood stream. Selective inhibition of SGLT2 is a potential strategy for reducing plasma glucose levels as a treatment for diabetes. Phlorizin is a natural product, first isolated from the bark of apple trees, that reduces plasma glucose levels by blocking renal and intestinal glucose absorption through inhibition of SGLT1 and SGLT2. It competitively inhibits the initial rate of a-methyl-D-glucopyranoside (a-MDG) uptake in human COS-1 cells expressing hSGLT1 and hSGLT2 with IC50 values of 400 and 65 nM, respectively. In HEK293T cells expressing human SGLT1 and SGLT2, phlorizin exhibits Ki values of 140 and 11 nM, respectively, at 37°C.

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