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ChemicalBook >> CAS DataBase List >> RDEA 594

RDEA 594

$8 - $940
Product name: RDEA 594
CAS: 878672-00-5
MF: C17H14BrN3O2S
MW: 404.28
EINECS:689-245-8
MDL Number:MFCD22572730
Synonyms:Lesinurad impurity1-12;RDEA 594;Lesinurad (with 3 ints.);Lesinurad (RDEA-594);2-{[5-broMo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid;2-[[5-BroMo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid;Lesurinad;Lesinuras

Price60 Properties Safety Information Description

60 prices

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aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
AvaChem
Biosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Sigma-Aldrich
TRC

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1mg
5mg
10mg
20mg
25mg
50mg
100mg
250mg
250.00mg
500MG
1.00g
1g
5.00g
10g
25g
10 mg
50 mg
10mM*1mLinDMSO

Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%
Packaging1mg
Price$8
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%
Packaging5mg
Price$10
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%
Packaging10mg
Price$12
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid ≥98%
Packaging25mg
Price$17
Updated2026-05-28
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Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid ≥98%
Packaging50mg
Price$18
Updated2026-05-28
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Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%
Packaging250mg
Price$31
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%
Packaging1g
Price$64
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%
Packaging10g
Price$474
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GR87
Product description2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%
Packaging25g
Price$940
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberM23708
Product description2-(5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid(Lesinurad (RDEA594)) 95%
Packaging500MG
Price$115
Updated2026-05-27
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ManufacturerAK Scientific
Product number3777AH
Product descriptionLesinurad
Packaging5mg
Price$45
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA3549
Product descriptionLesinurad
Packaging5mg
Price$55
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA3549
Product descriptionLesinurad
Packaging5mg
Price$55
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA3549
Product descriptionLesinurad
Packaging10mg
Price$70
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA3549
Product descriptionLesinurad
Packaging10mg
Price$72
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA3549
Product descriptionLesinurad
Packaging50mg
Price$187
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%	1mg	$8	2026-05-28	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%	5mg	$10	2026-05-28	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%	10mg	$12	2026-05-28	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid ≥98%	25mg	$17	2026-05-28	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid ≥98%	50mg	$18	2026-05-28	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%	250mg	$31	2026-05-28	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%	1g	$64	2026-05-28	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%	10g	$474	2026-05-28	Buy
aablocks	AA00GR87	2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid 98%	25g	$940	2026-05-28	Buy
ACHEMBLOCK	M23708	2-(5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid(Lesinurad (RDEA594)) 95%	500MG	$115	2026-05-27	Buy
AK Scientific	3777AH	Lesinurad	5mg	$45	2021-12-16	Buy
ApexBio Technology	A3549	Lesinurad	5mg	$55	2021-12-16	Buy
ApexBio Technology	A3549	Lesinurad	5mg	$55	2026-05-06	Buy
ApexBio Technology	A3549	Lesinurad	10mg	$70	2021-12-16	Buy
ApexBio Technology	A3549	Lesinurad	10mg	$72	2026-05-06	Buy
ApexBio Technology	A3549	Lesinurad	50mg	$187	2026-05-06	Buy

Next Last

Properties

Melting point :>171oC (dec.)
Boiling point :643.7±65.0 °C(Predicted)
Density :1.72±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
pka :2.91±0.10(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23)
InChIKey :FGQFOYHRJSUHMR-UHFFFAOYSA-N
SMILES :C(O)(=O)CSC1N(C2=C3C(C=CC=C3)=C(C3CC3)C=C2)C(Br)=NN=1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Approved by the FDA late in 2015, lesinurad is an urate anion exchange transporter 1 (URAT1) inhibitor for use in the treatment of gout. Ardea Biosciences, which is a subsidiary of AstraZeneca, developed lesinurad to be used in a combination therapy with xanthine oxidase inhibitors for the treatment of hyperuricaemia associated with gout. The approval process is ongoing in several other countries across the globe, with the EMA Committee for Medicinal Products for Human Use giving lesinurad a positive opinion for use as an adjunctive therapy in combination with xanthine oxidase inhibitors to treat hyperuricaemia.

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RDEA 594

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