RS 504393
|
- $45 - $1800
- Product name: RS 504393
- CAS: 300816-15-3
- MF: C25H27N3O3
- MW: 417.5
- EINECS:
- MDL Number:MFCD09038564
- Synonyms:Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-;6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidi;6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin]-2(;6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin];RS 504393;6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one;RS-504393; RS504393;RS504393 >=98% (HPLC)
66 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 250mg
- 10
- 250.00mg
- 1g
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 25MG
- 50mg
- 100MG
- Manufactureraablocks
- Product numberAA0035HU
- Product description6-METHYL-1'-[2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL]SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE 95%
- Packaging10mg
- Price$60
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035HU
- Product description6-METHYL-1'-[2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL]SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE ≥98%
- Packaging1mg
- Price$50
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127765
- Product descriptionRS 504393 98%
- Packaging100MG
- Price$435
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127765
- Product descriptionRS 504393 98%
- Packaging25MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3115AB
- Product descriptionRS504393
- Packaging5mg
- Price$177
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3115AB
- Product descriptionRS504393
- Packaging10mg
- Price$258
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA108264
- Product descriptionRs-504393 98+%
- Packaging25mg
- Price$272
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA108264
- Product descriptionRs-504393 98+%
- Packaging5mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA108264
- Product descriptionRs-504393 98+%
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000646
- Product descriptionRS 504393 95.00%
- Packaging1MG
- Price$148.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000646
- Product descriptionRS 504393 95.00%
- Packaging10MG
- Price$721.59
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3779
- Product descriptionRS504393
- Packaging10mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3779
- Product descriptionRS504393
- Packaging5mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3779
- Product descriptionRS 504393
- Packaging25mg
- Price$385
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3779
- Product descriptionRS 504393
- Packaging5mg
- Price$114
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3779
- Product descriptionRS 504393
- Packaging10mg
- Price$190
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0035HU | 6-METHYL-1'-[2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL]SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE 95% | 10mg | $60 | 2026-05-28 | Buy |
| aablocks | AA0035HU | 6-METHYL-1'-[2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL]SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE ≥98% | 1mg | $50 | 2026-05-28 | Buy |
| ACHEMBLOCK | U127765 | RS 504393 98% | 100MG | $435 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127765 | RS 504393 98% | 25MG | $145 | 2026-05-27 | Buy |
| AK Scientific | 3115AB | RS504393 | 5mg | $177 | 2021-12-16 | Buy |
| AK Scientific | 3115AB | RS504393 | 10mg | $258 | 2021-12-16 | Buy |
| Ambeed | A108264 | Rs-504393 98+% | 25mg | $272 | 2021-12-16 | Buy |
| Ambeed | A108264 | Rs-504393 98+% | 5mg | $108 | 2021-12-16 | Buy |
| Ambeed | A108264 | Rs-504393 98+% | 10mg | $160 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000646 | RS 504393 95.00% | 1MG | $148.05 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000646 | RS 504393 95.00% | 10MG | $721.59 | 2021-12-16 | Buy |
| ApexBio Technology | A3779 | RS504393 | 10mg | $260 | 2021-12-16 | Buy |
| ApexBio Technology | A3779 | RS504393 | 5mg | $156 | 2021-12-16 | Buy |
| ApexBio Technology | A3779 | RS 504393 | 25mg | $385 | 2026-05-06 | Buy |
| ApexBio Technology | A3779 | RS 504393 | 5mg | $114 | 2026-05-06 | Buy |
| ApexBio Technology | A3779 | RS 504393 | 10mg | $190 | 2026-05-06 | Buy |
Properties
Density :1.28
storage temp. :2-8°C
solubility :DMSO: soluble1mg/mL, clear (warmed)
form :powder
pka :13.390±0.20(predicted)
color :white to beige
InChI :1S/C25H27N3O3/c1-17-8-9-22-20(16-17)25(31-24(29)27-22)11-14-28(15-12-25)13-10-21-18(2)30-23(26-21)19-6-4-3-5-7-19/h3-9,16H,10-15H2,1-2H3,(H,27,29)
InChIKey :ODNICNWASXKNNQ-UHFFFAOYSA-N
SMILES :N3(CCC4(OC(=O)Nc5c4cc(cc5)C)CC3)CCc1nc([o]c1C)c2ccccc2
storage temp. :2-8°C
solubility :DMSO: soluble1mg/mL, clear (warmed)
form :powder
pka :13.390±0.20(predicted)
color :white to beige
InChI :1S/C25H27N3O3/c1-17-8-9-22-20(16-17)25(31-24(29)27-22)11-14-28(15-12-25)13-10-21-18(2)30-23(26-21)19-6-4-3-5-7-19/h3-9,16H,10-15H2,1-2H3,(H,27,29)
InChIKey :ODNICNWASXKNNQ-UHFFFAOYSA-N
SMILES :N3(CCC4(OC(=O)Nc5c4cc(cc5)C)CC3)CCc1nc([o]c1C)c2ccccc2
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
RS 504393 is an extremely selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys.More related product prices
4'-Hydroxyacetophenone Benzyl alcohol 16495-13-9 p-Tolualdehyde 2-Methylpropanedioic acid Octadecyl methacrylateRelated product price
-
4'-Hydroxyacetophenone
$5-2381 -
Benzyl alcohol
$5-16210 -
16495-13-9
$5-3980
