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ChemicalBook >> CAS DataBase List >> Raltegravir

Raltegravir

Raltegravir price.
  • $10 - $2841
  • Product name: Raltegravir
  • CAS: 518048-05-0
  • MF: C20H21FN6O5
  • MW: 444.42
  • EINECS:610-733-3
  • MDL Number:MFCD10698872
  • Synonyms:N-((4-Fluorophenyl)methyl)-1,6-dihydro-5-hydroxy-1-methyl-2-(1-methyl-1-(((5-methyl-1,3,4-oxadiazol-2;Raltegravir N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide;Raltegravir (free base) API;Raltegravir, >=99%;N-((4-Fluorophenyl)methyl)-1,6-dihydro-5-hydroxy-1-methyl-2-(1-methyl-1-(((5-methyl-1,3,4-oxadiazol-2-yl)carbonyl)amino)ethyl)-6-oxo-4-pyrimidinecarboxamide;N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide;Raltegravir;N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)p
96 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AstaTech
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • ChemScene
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  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 2mg
  • 25mg
  • 0.25G
  • 250.00mg
  • 500mg
  • 1.00g
  • 1000mg
  • 10mM*1mLinDMSO
  • 2000mg
  • 5.00g
  • 5000mg
  • 10000mg
  • 10g
  • 10mM(1mLinDMSO)
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 25G
  • 10mM(in1mLDMSO)
  • 10mM(in 1mL DMSO)
  • 1g
  • 5g
  • Manufactureraablocks
  • Product numberAA00I96U
  • Product descriptionN-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98%
  • Packaging250mg
  • Price$63
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I96U
  • Product descriptionN-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide ≥97%
  • Packaging50mg
  • Price$18
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I96U
  • Product descriptionN-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide ≥97%
  • Packaging10mg
  • Price$11
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I96U
  • Product descriptionN-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide ≥97%
  • Packaging5mg
  • Price$10
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I96U
  • Product descriptionN-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98%
  • Packaging1g
  • Price$174
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I96U
  • Product descriptionN-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98%
  • Packaging5g
  • Price$609
  • Updated2026-05-29
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  • ManufacturerACHEMBLOCK
  • Product numberX212464
  • Product descriptionRaltegravir (MK-0518) 97%
  • Packaging1G
  • Price$165
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberX212464
  • Product descriptionRaltegravir (MK-0518) 97%
  • Packaging5G
  • Price$660
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberX212464
  • Product descriptionRaltegravir (MK-0518) 97%
  • Packaging25G
  • Price$1715
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product numberX0050
  • Product descriptionRaltegravir
  • Packaging250mg
  • Price$199
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121488
  • Product descriptionN-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98%
  • Packaging5mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121488
  • Product descriptionN-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98%
  • Packaging10mg
  • Price$38
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000049
  • Product descriptionRALTEGRAVIR 95.00%
  • Packaging1G
  • Price$550
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000049
  • Product descriptionRALTEGRAVIR 95.00%
  • Packaging250MG
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4073
  • Product descriptionRaltegravir (MK-0518)
  • Packaging50mg
  • Price$425
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4073
  • Product descriptionRaltegravir(MK-0518)
  • Packaging50mg
  • Price$390
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I96U N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98% 250mg $63 2026-05-29 Buy
aablocks AA00I96U N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide ≥97% 50mg $18 2026-05-29 Buy
aablocks AA00I96U N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide ≥97% 10mg $11 2026-05-29 Buy
aablocks AA00I96U N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide ≥97% 5mg $10 2026-05-29 Buy
aablocks AA00I96U N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98% 1g $174 2026-05-29 Buy
aablocks AA00I96U N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98% 5g $609 2026-05-29 Buy
ACHEMBLOCK X212464 Raltegravir (MK-0518) 97% 1G $165 2026-05-27 Buy
ACHEMBLOCK X212464 Raltegravir (MK-0518) 97% 5G $660 2026-05-27 Buy
ACHEMBLOCK X212464 Raltegravir (MK-0518) 97% 25G $1715 2026-05-27 Buy
AK Scientific X0050 Raltegravir 250mg $199 2021-12-16 Buy
Ambeed A121488 N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98% 5mg $29 2021-12-16 Buy
Ambeed A121488 N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide 98% 10mg $38 2021-12-16 Buy
American Custom Chemicals Corporation INB0000049 RALTEGRAVIR 95.00% 1G $550 2021-12-16 Buy
American Custom Chemicals Corporation INB0000049 RALTEGRAVIR 95.00% 250MG $460 2021-12-16 Buy
ApexBio Technology A4073 Raltegravir (MK-0518) 50mg $425 2026-05-06 Buy
ApexBio Technology A4073 Raltegravir(MK-0518) 50mg $390 2021-12-16 Buy

Properties

Melting point :216 °C(Solv: isopropanol (67-63-0))
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Very Slightly)
pka :4.50±1.00(Predicted)
form :Solid
color :White to Light Beige
Henry's Law Constant :1.1×1017 mol/(m3Pa) at 25℃, HSDB (2015)
InChI :InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)
InChIKey :CZFFBEXEKNGXKS-UHFFFAOYSA-N
SMILES :C1(C(C)(NC(C2=NN=C(C)O2)=O)C)N(C)C(=O)C(O)=C(C(NCC2=CC=C(F)C=C2)=O)N=1
CAS DataBase Reference :518048-05-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Joining maraviroc as a unique approach to battling HIV-1, raltegravir, an inhibitor of HIV-1 integrase, represents the first in its class to be developed and launched as a combination treatment with other antiretroviral agents (NRTIs, NNRTIs, and PIs). HIV-1 integrase is essential for replication of the virus as a virally encoded enzyme that integrates the viral DNA into the genome of the host cell. Inhibition of HIV-1 integrase prevents the two-step process of endonucleolytic removal of the terminal dinucleotide from each 3′end of the viral DNA followed by the covalent integration of the viral DNA, at these modified 3′ends, into the host DNA, thereby representing a viable intervention in the viral life cycle. In vitro, raltegravir inhibited the strand transfer activity of HIV-1 integrase with an IC50 of 2–7nM with > 1,000-fold selectivity over other phosphoryltransferases. In addition, its in vitro IC95 for HIV-1 in 10% fetal bovine serum and 50% human serum was 19 and 33 nM, respectively. Raltegravir was well tolerated with no dose-related toxicities and a safety profile comparable to placebo. The most common clinical adverse events were diarrhea, nausea, vomiting, fatigue, headache, flushing, pruritus, and injection-site reactions.

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