ReModelin
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- $47 - $1830
- Product name: ReModelin
- CAS: 949912-58-7
- MF: C15H14N4S
- MW: 282.36
- EINECS:
- MDL Number:MFCD28167837
- Synonyms:ReModelin;4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile hydrobromide;4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile;CS-2149;Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-;Reaxys ID: 18559527;4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile;4- (2- (2-cyclopentylidenehydrazine) thiazol-4-yl) benzonitrile
57 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- AvaChem
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10
- 2mg
- 50
- 1mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 2x5mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250MG
- 10mM*1mLinDMSO(Solid+Solvent)
- 1G
- 25 mg
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA01DNQE
- Product description4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile
- Packaging2mg
- Price$47
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQE
- Product description4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile
- Packaging5mg
- Price$60
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQE
- Product description4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile
- Packaging10mg
- Price$76
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQE
- Product description4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile
- Packaging25mg
- Price$126
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQE
- Product description4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile
- Packaging50mg
- Price$176
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQE
- Product description4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile
- Packaging100mg
- Price$231
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQE
- Product description4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile
- Packaging200mg
- Price$334
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227960
- Product descriptionRemodelin 97.00%
- Packaging100MG
- Price$425
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227960
- Product descriptionRemodelin 97.00%
- Packaging250MG
- Price$680
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227960
- Product descriptionRemodelin 97.00%
- Packaging1G
- Price$1830
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5222
- Product descriptionRemodelin
- Packaging10mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-16706
- Product descriptionRemodelin 99.84%
- Packaging25mg
- Price$171
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16706
- Product descriptionRemodelin 99.84%
- Packaging50mg
- Price$228
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16706
- Product descriptionRemodelin 99.84%
- Packaging100mg
- Price$304
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16706
- Product descriptionRemodelin 99.84%
- Packaging10mg
- Price$95
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16706
- Product descriptionRemodelin 99.84%
- Packaging5mg
- Price$63
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01DNQE | 4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile | 2mg | $47 | 2026-05-29 | Buy |
| aablocks | AA01DNQE | 4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile | 5mg | $60 | 2026-05-29 | Buy |
| aablocks | AA01DNQE | 4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile | 10mg | $76 | 2026-05-29 | Buy |
| aablocks | AA01DNQE | 4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile | 25mg | $126 | 2026-05-29 | Buy |
| aablocks | AA01DNQE | 4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile | 50mg | $176 | 2026-05-29 | Buy |
| aablocks | AA01DNQE | 4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile | 100mg | $231 | 2026-05-29 | Buy |
| aablocks | AA01DNQE | 4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile | 200mg | $334 | 2026-05-29 | Buy |
| ACHEMBLOCK | Y227960 | Remodelin 97.00% | 100MG | $425 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227960 | Remodelin 97.00% | 250MG | $680 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227960 | Remodelin 97.00% | 1G | $1830 | 2026-05-27 | Buy |
| AK Scientific | SYN5222 | Remodelin | 10mg | $165 | 2021-12-16 | Buy |
| Arctom | HY-16706 | Remodelin 99.84% | 25mg | $171 | 2026-05-26 | Buy |
| Arctom | HY-16706 | Remodelin 99.84% | 50mg | $228 | 2026-05-26 | Buy |
| Arctom | HY-16706 | Remodelin 99.84% | 100mg | $304 | 2026-05-26 | Buy |
| Arctom | HY-16706 | Remodelin 99.84% | 10mg | $95 | 2026-05-26 | Buy |
| Arctom | HY-16706 | Remodelin 99.84% | 5mg | $63 | 2026-05-26 | Buy |
Properties
Boiling point :498.9±47.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :14.40±0.20(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :1S/C15H14N4S.BrH/c16-9-11-5-7-12(8-6-11)14-10-20-15(17-14)19-18-13-3-1-2-4-13;/h5-8,10H,1-4H2,(H,17,19);1H
InChIKey :XNWBCMSPDCSWSD-UHFFFAOYSA-N
SMILES :N#CC(C=C1)=CC=C1C2=CSC(NN=C3CCCC3)=N2.Br
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :14.40±0.20(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :1S/C15H14N4S.BrH/c16-9-11-5-7-12(8-6-11)14-10-20-15(17-14)19-18-13-3-1-2-4-13;/h5-8,10H,1-4H2,(H,17,19);1H
InChIKey :XNWBCMSPDCSWSD-UHFFFAOYSA-N
SMILES :N#CC(C=C1)=CC=C1C2=CSC(NN=C3CCCC3)=N2.Br
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 μM, improves nuclear architecture, chromatin organization, and survival of both cells lacking lamin A and cells from patients with progeria. Remodelin is an inhibitor of N-acetyltransferase 10 (NAT10), which acetylates both histones and microtubules. Mutation of NAT10 mimics the effects of remodelin on nuclear morphology, suggesting that these effects of remodelin require NAT10. Remodelin also has cytotoxic effects against some species of the fungus Candida.Related product price
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