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ChemicalBook >> CAS DataBase List >> SKI II

SKI II

$13 - $2841
Product name: SKI II
CAS: 312636-16-1
MF: C15H11ClN2OS
MW: 302.78
EINECS:
MDL Number:MFCD00733553
Synonyms:Sphingosine Kinase Inhibitor;Sphingosine Kinase Inhibitor 2;SKI II (SphK-I2);SphK-I2;SKI II (Sphingosine Kinase Inhibitor);Phenol, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-;4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol SKI II;4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol

Price109 Properties Safety Information Description

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A2B
aablocks
ACHEMBLOCK
AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
Sigma-Aldrich
Thermo Scientific Chemicals
TRC
Usbiological

Package

10mM(in1mLDMSO)
10mM(in 1mL DMSO)
25.00mg
10mM(1mLinDMSO)
1mg
5mg
10mg
25mg
50mg
50.00mg
100mg
100.00mg
200mg
250mg
500mg
1G

ManufacturerA2B
Product numberAB49335
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging1mg
Price$13
Updated2026-05-25
Buy

ManufacturerA2B
Product numberAB49335
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging5mg
Price$25
Updated2026-05-25
Buy

ManufacturerA2B
Product numberAB49335
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging10mg
Price$27
Updated2026-05-25
Buy

ManufacturerA2B
Product numberAB49335
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging25mg
Price$51
Updated2026-05-25
Buy

ManufacturerA2B
Product numberAB49335
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging50mg
Price$87
Updated2026-05-25
Buy

ManufacturerA2B
Product numberAB49335
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging100mg
Price$137
Updated2026-05-25
Buy

ManufacturerA2B
Product numberAB49335
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging250mg
Price$233
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA0037AZ
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging5mg
Price$27
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037AZ
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging1mg
Price$14
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037AZ
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging100mg
Price$152
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037AZ
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging250mg
Price$260
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037AZ
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging50mg
Price$99
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037AZ
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging25mg
Price$63
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037AZ
Product description4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%
Packaging10mg
Price$38
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberO33948
Product descriptionSKI II 98%
Packaging250MG
Price$200
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberO33948
Product descriptionSKI II 98%
Packaging1G
Price$520
Updated2026-05-27
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
A2B	AB49335	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	1mg	$13	2026-05-25	Buy
A2B	AB49335	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	5mg	$25	2026-05-25	Buy
A2B	AB49335	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	10mg	$27	2026-05-25	Buy
A2B	AB49335	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	25mg	$51	2026-05-25	Buy
A2B	AB49335	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	50mg	$87	2026-05-25	Buy
A2B	AB49335	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	100mg	$137	2026-05-25	Buy
A2B	AB49335	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	250mg	$233	2026-05-25	Buy
aablocks	AA0037AZ	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	5mg	$27	2026-05-28	Buy
aablocks	AA0037AZ	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	1mg	$14	2026-05-28	Buy
aablocks	AA0037AZ	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	100mg	$152	2026-05-28	Buy
aablocks	AA0037AZ	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	250mg	$260	2026-05-28	Buy
aablocks	AA0037AZ	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	50mg	$99	2026-05-28	Buy
aablocks	AA0037AZ	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	25mg	$63	2026-05-28	Buy
aablocks	AA0037AZ	4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol 98%	10mg	$38	2026-05-28	Buy
ACHEMBLOCK	O33948	SKI II 98%	250MG	$200	2026-05-27	Buy
ACHEMBLOCK	O33948	SKI II 98%	1G	$520	2026-05-27	Buy

Next Last

Properties

Boiling point :507.1±60.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
RTECS :SK5900000
storage temp. :2-8°C
solubility :DMSO: ≥20 mg/mL
form :solid
pka :10.17±0.26(Predicted)
color :off-white
Sensitive :Air & Light Sensitive
InChI :1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18)
InChIKey :ZFGXZJKLOFCECI-UHFFFAOYSA-N
SMILES :Oc1ccc(Nc2nc(cs2)-c3ccc(Cl)cc3)cc1
CAS DataBase Reference :312636-16-1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SKI II is a selective non-lipid inhibitor of SphK(sphingosine kinase) (IC₅₀ = 0.5 M); does not act at ATP-binding site. SKI II displays no inhibition of ERK2, PI 3-kinase, or PKCα at concentrations up to 60 μM. Reduces levels of sphingosine-1-phosphate in MDA-MB-231 breast cancer cells. SKI II induces apoptosis and inhibits prpliferation in several other tumor cell lines in vitro (IC₅₀ = 0.9-4.6 μM).

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Suppliers and manufacturers

TargetMol Chemicals Inc.

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SKI II

Properties

Safety Information

Description

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