Shikonin
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- $11 - $2245.7
- Product name: Shikonin
- CAS: 517-89-5
- MF: C16H16O5
- MW: 288.3
- EINECS:
- MDL Number:MFCD00075680
- Synonyms:5,8-Dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione;Tokyo Violet;(R)-5,8-Dihydroxy-2-(1-hydroxy-4-Methylpent-3-en-1-yl)naphthalene-1,4-dione;SHIKONIN(AS);Shikonin, froM Arnebia sp.;(-)-ShikoninChina;Shikonine;Shikonin 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione
97 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 10mg
- 5mg
- 1mlx10mM(inDMSO)
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1000mg
- 1G
- Manufactureraablocks
- Product numberAA0037A6
- Product description5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione ≥98%
- Packaging5mg
- Price$30
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037A6
- Product description5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione 97%(extract,contains~8%S-enantiomer)
- Packaging25mg
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037A6
- Product description5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione 97%(extract,contains~8%S-enantiomer)
- Packaging50mg
- Price$81
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037A6
- Product description5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione 97%(extract,contains~8%S-enantiomer)
- Packaging100mg
- Price$136
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037A6
- Product description5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione 97%(extract,contains~8%S-enantiomer)
- Packaging250mg
- Price$230
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193341
- Product description(R)-(+)-Shikonin 98.00%
- Packaging250MG
- Price$340
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193341
- Product description(R)-(+)-Shikonin 98.00%
- Packaging250MG
- Price$340
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193341
- Product description(R)-(+)-Shikonin 98.00%
- Packaging100MG
- Price$140
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193341
- Product description(R)-(+)-Shikonin 98.00%
- Packaging100MG
- Price$140
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193341
- Product description(R)-(+)-Shikonin 98.00%
- Packaging1G
- Price$890
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193341
- Product description(R)-(+)-Shikonin 98.00%
- Packaging1G
- Price$890
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0487-M010
- Product descriptionShikonin ≥98%(HPLC)
- Packaging10mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0487-M050
- Product descriptionShikonin ≥98%(HPLC)
- Packaging50mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0487-M050
- Product descriptionShikonin ≥98%(HPLC)
- Packaging50mg
- Price$170
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberI664
- Product descriptionShikonin
- Packaging50mg
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI664
- Product descriptionShikonin
- Packaging10mg
- Price$67
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0037A6 | 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione ≥98% | 5mg | $30 | 2026-05-28 | Buy |
| aablocks | AA0037A6 | 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione 97%(extract,contains~8%S-enantiomer) | 25mg | $48 | 2026-05-28 | Buy |
| aablocks | AA0037A6 | 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione 97%(extract,contains~8%S-enantiomer) | 50mg | $81 | 2026-05-28 | Buy |
| aablocks | AA0037A6 | 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione 97%(extract,contains~8%S-enantiomer) | 100mg | $136 | 2026-05-28 | Buy |
| aablocks | AA0037A6 | 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione 97%(extract,contains~8%S-enantiomer) | 250mg | $230 | 2026-05-28 | Buy |
| ACHEMBLOCK | X193341 | (R)-(+)-Shikonin 98.00% | 250MG | $340 | 2026-05-25 | Buy |
| ACHEMBLOCK | X193341 | (R)-(+)-Shikonin 98.00% | 250MG | $340 | 2026-05-27 | Buy |
| ACHEMBLOCK | X193341 | (R)-(+)-Shikonin 98.00% | 100MG | $140 | 2026-05-25 | Buy |
| ACHEMBLOCK | X193341 | (R)-(+)-Shikonin 98.00% | 100MG | $140 | 2026-05-27 | Buy |
| ACHEMBLOCK | X193341 | (R)-(+)-Shikonin 98.00% | 1G | $890 | 2026-05-25 | Buy |
| ACHEMBLOCK | X193341 | (R)-(+)-Shikonin 98.00% | 1G | $890 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CN2-0487-M010 | Shikonin ≥98%(HPLC) | 10mg | $50 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0487-M050 | Shikonin ≥98%(HPLC) | 50mg | $160 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0487-M050 | Shikonin ≥98%(HPLC) | 50mg | $170 | 2026-05-06 | Buy |
| AK Scientific | I664 | Shikonin | 50mg | $188 | 2021-12-16 | Buy |
| AK Scientific | I664 | Shikonin | 10mg | $67 | 2021-12-16 | Buy |
Properties
Melting point :148℃
Boiling point :567.4±50.0 °C(Predicted)
Density :1.373±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO : ≥ 31 mg/mL (107.53 mM);
pka :7.34±0.20(Predicted)
form :Red crystalline solid.
color :Brown
Henry's Law Constant :1.2×109 mol/(m3Pa) at 25℃, HSDB (2015)
Major Application :food and beverages
Cosmetics Ingredients Functions :COLORANT
SKIN CONDITIONING - MISCELLANEOUS InChI :InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m1/s1
InChIKey :NEZONWMXZKDMKF-SNVBAGLBSA-N
SMILES :C1(=O)C2=C(C(O)=CC=C2O)C(=O)C=C1[C@H](O)C/C=C(\C)/C
LogP :4.350 (est)
CAS DataBase Reference :517-89-5(CAS DataBase Reference)
Boiling point :567.4±50.0 °C(Predicted)
Density :1.373±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO : ≥ 31 mg/mL (107.53 mM);
pka :7.34±0.20(Predicted)
form :Red crystalline solid.
color :Brown
Henry's Law Constant :1.2×109 mol/(m3Pa) at 25℃, HSDB (2015)
Major Application :food and beverages
Cosmetics Ingredients Functions :COLORANT
SKIN CONDITIONING - MISCELLANEOUS InChI :InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m1/s1
InChIKey :NEZONWMXZKDMKF-SNVBAGLBSA-N
SMILES :C1(=O)C2=C(C(O)=CC=C2O)C(=O)C=C1[C@H](O)C/C=C(\C)/C
LogP :4.350 (est)
CAS DataBase Reference :517-89-5(CAS DataBase Reference)
Safety Information
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Description
Shikonin is a naturally occurring naphthoquinine isolated from the dried root of L. erythrorhizon, an herb used in traditional Chinese medicine. It increases glucose uptake by adipocytes and myocytes and inhibits the activity of phosphatase and tensin homolog (PTEN; IC50 = 2.7 μM). It inhibits glycolysis in cancer cells by inhibiting tumor-specific pyruvate kinase M2 (IC50 = 0.3 μM). Shikonin induces cell death consistent with necroptosis in MCF-7 and HEK293 cancer cell lines. It inhibits leukocyte migration, downregulates chemokine receptor expression, and inhibits HIV-1 replication at nanomolar concentrations. Shikonin exhibits anti-inflammatory activity, reducing joint swelling and cartilage destruction in a mouse model of collagen-induced arthritis.Suppliers and manufacturers
Shaanxi Xianhe Biotech Co., Ltd
BOC Sciences
Henan Tianfu Chemical Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Greenpure Biopharma CO.,Ltd
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Shandong chuangyingchemical Co., Ltd.
Shikonin
CAS:517-89-5
![5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione](https://img.chemicalbook.com/ProductImageEN/2018-12/small/027035a7-de5d-4298-bea1-9acd2fce4903.png){kind=small}