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ChemicalBook >> CAS DataBase List >> Tadalafil

Tadalafil

$8 - $1932.5
Product name: Tadalafil
CAS: 171596-29-5
MF: C22H19N3O4
MW: 389.4
EINECS:687-782-2
MDL Number:MFCD07771966
Synonyms:ICOS 351;UK 336017;TADALAFIL(CIALIS);Taladafil (cialis);Cialis/taladafil;(6r,12ar)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;Cialis ,98%;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-

Price109 Properties Safety Information Description

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aablocks
ACHEMBLOCK
Adipogen Life Sciences
AK Scientific
ApexBio Technology
Arctom
AvaChem
Biosynth
Cayman Chemical
Chemcia Scientific
ChemScene
Chemtos
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
Sigma-Aldrich
TCI Chemical
Thermo Scientific Chemicals
Tocris
TRC
Usbiological

Package

10mM*1mLinDMSO(Solid+Solvent)
1mg
10mM(in 1mL DMSO)
10mg
10
5mg
10mM*1mLinDMSO(Solution)
y0001417
20mg
25mg
50mg
100mg
200mg
250mg
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1mL
1g
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Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%
Packaging10mg
Price$10
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%
Packaging50mg
Price$10
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%
Packaging100mg
Price$11
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%
Packaging250mg
Price$13
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%
Packaging500mg
Price$15
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%
Packaging1g
Price$16
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%
Packaging1mg
Price$8
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%
Packaging5g
Price$22
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%
Packaging10g
Price$34
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%
Packaging25g
Price$44
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%
Packaging100g
Price$139
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%
Packaging500g
Price$455
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0037UI
Product description(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%
Packaging1000g
Price$773
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberL22148
Product descriptionTadalafil 98%
Packaging500MG
Price$345
Updated2026-05-27
Buy

ManufacturerAdipogen Life Sciences
Product numberCDX-T0455-M500
Product descriptionTadalafil ≥98%
Packaging500mg
Price$460
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberCDX-T0455-M050
Product descriptionTadalafil ≥98%
Packaging50mg
Price$73
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%	10mg	$10	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%	50mg	$10	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%	100mg	$11	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%	250mg	$13	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%	500mg	$15	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione ≥99%	1g	$16	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%	1mg	$8	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%	5g	$22	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%	10g	$34	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%	25g	$44	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%	100g	$139	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%	500g	$455	2026-05-28	Buy
aablocks	AA0037UI	(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione 98%	1000g	$773	2026-05-28	Buy
ACHEMBLOCK	L22148	Tadalafil 98%	500MG	$345	2026-05-27	Buy
Adipogen Life Sciences	CDX-T0455-M500	Tadalafil ≥98%	500mg	$460	2026-05-06	Buy
Adipogen Life Sciences	CDX-T0455-M050	Tadalafil ≥98%	50mg	$73	2026-05-06	Buy

Next Last

Properties

Melting point :298-300°C
alpha :D20 +71.0°
Boiling point :679.1±55.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :16.68±0.40(Predicted)
color :white to beige
optical activity :[α]/D +68 to +78°, c = 1 in chloroform-d
Henry's Law Constant :2.0×10¹² mol/(m³Pa) at 25℃, HSDB (2015)
BCS Class :4
Stability :Unstable in Methanol
Major Application :pharmaceutical (small molecule)
InChI :InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
InChIKey :WOXKDUGGOYFFRN-IIBYNOLFSA-N
SMILES :N1C2=C(C=CC=C2)C2C[C@]3([H])C(=O)N(C)CC(=O)N3[C@H](C3=CC=C4OCOC4=C3)C1=2
CAS DataBase Reference :171596-29-5(CAS DataBase Reference)

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tadalafil (market name “Cialis” or “Adcirca”) is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. The effect of Tadalafil is relaxing the blood vessels muscles and increasing the blood flow into the corpus cavernosum. The mechanism of action of tadalafil is through inhibiting the activity of the cGMP specific phosphodiesterase type 5 (PDE5). PDE5 degrades cGMP in the corpus cavernosum located around the penis. Therefore, tadalafi leads to the increased concentration of cGMP which further causes the smooth muscle relaxation and increased blood flow into the corpus cavernosum. Some clinical studies also implied that tadalafil could improve endothelia function in men with increased cardiovascular risk and lower the urinary tract symptoms secondary to benign prostatic hyperplasia.

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Suppliers and manufacturers

Shaanxi Linkyou Biotechnology Co., Ltd.

$5.00
Tadalafil (Cialis) CAS:171596-29-5

Hebei Jiafan Trading Company Limited

$5.00
Tadanafil CAS:171596-29-5

RongNa Biotechnology Co.,Ltd

$10.00
Tadalafil CAS:171596-29-5

Hangzhou Hyper Chemicals Limited

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Shandong Fengjin Pharmaceutical Co., Ltd.

$205.00
Tadalafil CAS:171596-29-5

.GZ HONESTCHEM CO.,LTD

$1.00
Tildenafil CAS:171596-29-5

Shaanxi Dideu Medichem Co. Ltd

Tadalafil CAS:171596-29-5

Hebei Dangtong Import and export Co LTD

$240.00
Tadalafil CAS:171596-29-5

Shanghai Longyu Biotechnology Co., Ltd.

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd.

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Tadalafil

Properties

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Description

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