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ChemicalBook >> CAS DataBase List >> Temocapril hydrochloride

Temocapril hydrochloride

Temocapril hydrochloride price.
  • $12 - $2170
  • Product name: Temocapril hydrochloride
  • CAS: 110221-44-8
  • MF: C23H28N2O5S2.ClH
  • MW: 513.076
  • EINECS:1312995-182-4
  • MDL Number:MFCD00933433
  • Synonyms:TEMOCAPRIL HYDROCHLORIDE;Acecol;CS-622;1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, (2S,6R)- (9CI);1,4-Thiazepine-4(5H)-acetic acid, 6-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, [2S-[2a,6b(R*)]]-;Temocapril Hcl ;TemocarpileHCL;Temocarpilhydrochloride
74 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • EvaluationSample
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM(in1mLDMSO)
  • 1mg
  • 5mg
  • 10mg
  • 10.00mg
  • 10mM*1mLinDMSO(Solution)
  • 25mg
  • 50mg
  • 50.00mg
  • 100mg
  • 200mg
  • 250MG
  • 1g
  • 1.00g
  • Manufactureraablocks
  • Product numberAA01CCI8
  • Product descriptionTemocapril Hydrochloride 99%(HPLC)
  • Packaging1mg
  • Price$12
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA01CCI8
  • Product descriptionTemocapril Hydrochloride 98%
  • Packaging5mg
  • Price$30
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA01CCI8
  • Product descriptionTemocapril Hydrochloride 99%(HPLC)
  • Packaging10mg
  • Price$32
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA01CCI8
  • Product descriptionTemocapril Hydrochloride 98
  • Packaging50mg
  • Price$138
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA01CCI8
  • Product descriptionTemocapril Hydrochloride 98
  • Packaging100mg
  • Price$203
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA01CCI8
  • Product descriptionTemocapril Hydrochloride 98
  • Packaging200mg
  • Price$294
  • Updated2026-05-29
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  • ManufacturerACHEMBLOCK
  • Product numberS88145
  • Product description2-((2S)-6-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride 98%
  • Packaging250MG
  • Price$540
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS88145
  • Product description2-((2S)-6-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride 98%
  • Packaging250MG
  • Price$540
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS88145
  • Product description2-((2S)-6-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride 98%
  • Packaging100MG
  • Price$270
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS88145
  • Product description2-((2S)-6-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride 98%
  • Packaging100MG
  • Price$270
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product numberO388
  • Product descriptionTemocapril HCl 98%
  • Packaging100mg
  • Price$247
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberO388
  • Product descriptionTemocapril HCl 98%
  • Packaging5mg
  • Price$27
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberO388
  • Product descriptionTemocapril HCl 98%
  • Packaging50mg
  • Price$137
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberO388
  • Product descriptionTemocapril HCl 98%
  • Packaging25mg
  • Price$86
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberO388
  • Product descriptionTemocaprilHCl
  • Packaging5mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberO388
  • Product descriptionTemocapril HCl 98%
  • Packaging10mg
  • Price$48
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01CCI8 Temocapril Hydrochloride 99%(HPLC) 1mg $12 2026-05-29 Buy
aablocks AA01CCI8 Temocapril Hydrochloride 98% 5mg $30 2026-05-29 Buy
aablocks AA01CCI8 Temocapril Hydrochloride 99%(HPLC) 10mg $32 2026-05-29 Buy
aablocks AA01CCI8 Temocapril Hydrochloride 98 50mg $138 2026-05-29 Buy
aablocks AA01CCI8 Temocapril Hydrochloride 98 100mg $203 2026-05-29 Buy
aablocks AA01CCI8 Temocapril Hydrochloride 98 200mg $294 2026-05-29 Buy
ACHEMBLOCK S88145 2-((2S)-6-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride 98% 250MG $540 2026-05-27 Buy
ACHEMBLOCK S88145 2-((2S)-6-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride 98% 250MG $540 2026-05-25 Buy
ACHEMBLOCK S88145 2-((2S)-6-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride 98% 100MG $270 2026-05-27 Buy
ACHEMBLOCK S88145 2-((2S)-6-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride 98% 100MG $270 2026-05-25 Buy
AK Scientific O388 Temocapril HCl 98% 100mg $247 2026-06-04 Buy
AK Scientific O388 Temocapril HCl 98% 5mg $27 2026-06-04 Buy
AK Scientific O388 Temocapril HCl 98% 50mg $137 2026-06-04 Buy
AK Scientific O388 Temocapril HCl 98% 25mg $86 2026-06-04 Buy
AK Scientific O388 TemocaprilHCl 5mg $25 2021-12-16 Buy
AK Scientific O388 Temocapril HCl 98% 10mg $48 2026-06-04 Buy

Properties

Melting point :196-2000C (dec)
alpha :25D +47.7° (c = 1 in DMF)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
InChIKey :XDDQNOKKZKHBIX-VQDSPBDZNA-N
SMILES :[C@@H]1(SC[C@H](N[C@H](C(=O)OCC)CCC2C=CC=CC=2)C(=O)N(CC(=O)O)C1)C1SC=CC=1.Cl |&1:0,3,5,r|
CAS DataBase Reference :110221-44-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension. Temocapril is a prodrug of the ACE inhibitor, temocaprilat (IC50 = 3.6 and 7.6 nM in isolated rat lung and aorta, respectively). Upon oral administration it is rapidly deesterified to the active form, which remains long acting until excreted in bile and urine. In clinical trials, it has been used to reduce blood pressure, improve endothelial dysfunction, and prevent vascular remodeling, as well as improve insulin sensitivity and renal function in certain hypertensive or diabetic conditions.

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