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ChemicalBook >> CAS DataBase List >> Temsirolimus

Temsirolimus

Temsirolimus price.
  • $18 - $2841
  • Product name: Temsirolimus
  • CAS: 162635-04-3
  • MF: C56H87NO16
  • MW: 1030.29
  • EINECS:686-177-0
  • MDL Number:MFCD00934421
  • Synonyms:42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropa;Temsirolimus(CCI-779);TEMSIROLIMUS;CCL-779;Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate;TeMsiroliMus (CCI-779, Torisel);rapaMycin 42-ester with 3-hydroxy-2-(hydroxyMethyl)-2-Methylpropionic acid;42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin
112 prices
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  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Thermo Scientific Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 20mg
  • 500mg
  • 10mM*1mLinDMSO(Solution)
  • EvaluationSample
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10.00g
  • 25.00g
  • 10
  • 10mM*1mLinDMSO
  • 100.00g
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1G
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA00IMI9
  • Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95%
  • Packaging1mg
  • Price$18
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IMI9
  • Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95%
  • Packaging5mg
  • Price$37
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IMI9
  • Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95%
  • Packaging10mg
  • Price$55
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IMI9
  • Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95%
  • Packaging25mg
  • Price$107
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IMI9
  • Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin ≥98%
  • Packaging100mg
  • Price$406
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IMI9
  • Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin ≥98%(HPLC)
  • Packaging250mg
  • Price$705
  • Updated2026-05-29
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10394
  • Product descriptionTemsirolimus 98%
  • Packaging1G
  • Price$1215
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10394
  • Product descriptionTemsirolimus 98%
  • Packaging25MG
  • Price$135
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product number10394
  • Product descriptionTemsirolimus 98%
  • Packaging5MG
  • Price$50
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product number10394
  • Product descriptionTemsirolimus 98%
  • Packaging100MG
  • Price$356
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberB622
  • Product descriptionTemsirolimus
  • Packaging25mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberB622
  • Product descriptionTemsirolimus
  • Packaging1mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA642622
  • Product descriptionTemsirolimus 99%
  • Packaging5mg
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA642622
  • Product descriptionTemsirolimus 99%
  • Packaging10mg
  • Price$69
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA642622
  • Product descriptionTemsirolimus 99%
  • Packaging25mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA642622
  • Product descriptionTemsirolimus 99%
  • Packaging100mg
  • Price$382
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00IMI9 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95% 1mg $18 2026-05-29 Buy
aablocks AA00IMI9 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95% 5mg $37 2026-05-29 Buy
aablocks AA00IMI9 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95% 10mg $55 2026-05-29 Buy
aablocks AA00IMI9 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95% 25mg $107 2026-05-29 Buy
aablocks AA00IMI9 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin ≥98% 100mg $406 2026-05-29 Buy
aablocks AA00IMI9 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin ≥98%(HPLC) 250mg $705 2026-05-29 Buy
ACHEMBLOCK 10394 Temsirolimus 98% 1G $1215 2026-05-27 Buy
ACHEMBLOCK 10394 Temsirolimus 98% 25MG $135 2026-05-27 Buy
ACHEMBLOCK 10394 Temsirolimus 98% 5MG $50 2026-05-27 Buy
ACHEMBLOCK 10394 Temsirolimus 98% 100MG $356 2026-05-27 Buy
AK Scientific B622 Temsirolimus 25mg $257 2021-12-16 Buy
AK Scientific B622 Temsirolimus 1mg $49 2021-12-16 Buy
Ambeed A642622 Temsirolimus 99% 5mg $46 2021-12-16 Buy
Ambeed A642622 Temsirolimus 99% 10mg $69 2021-12-16 Buy
Ambeed A642622 Temsirolimus 99% 25mg $146 2021-12-16 Buy
Ambeed A642622 Temsirolimus 99% 100mg $382 2021-12-16 Buy

Properties

Melting point :99-101°C
Boiling point :1048.4±75.0 °C(Predicted)
Density :1.21
Flash point :587.8℃
storage temp. :room temp
solubility :Soluble in chloroform, methanol.
pka :10.40±0.70(Predicted)
form :powder
color :white to off-white
Merck :14,9142
InChIKey :CBPNZQVSJQDFBE-FUXHJELOSA-N

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Rapamycin is an immunosuppressant that specifically interacts with the cytosolic FK-binding protein 12 to form a complex which inhibits the mammalian target of rapamycin (mTOR) pathway by directly binding to mTOR Complex 1. Temsirolimus is a dihydroxymethyl propionic acid ester of rapamycin with improved solubility that specifically inhibits mTOR signaling with a potency similar to that of rapamycin. Treatment with temsirolimus leads to cell cycle arrest in the G1 phase and also inhibition of tumor angiogenesis by reducing synthesis of VEGF. Temsirolimus demonstrates cytostatic activity in several xenograft models of human tumors in nude mice, including glioblastomas, prostate carcinoma, pancreatic, liver, and breast cancers, and medulloblastoma.

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