Tezacaftor
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- $9 - $1600
- Product name: Tezacaftor
- CAS: 1152311-62-0
- MF: C26H27F3N2O6
- MW: 520.5
- EINECS:
- MDL Number:MFCD23106064
- Synonyms:VX-661/VX661;Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-;1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide VX661;(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-;CS-956;VX661/Tezacaftor;VX 661; VX661;VX-661;1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
67 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 0.025g
- 0.05g
- 0.1g
- 0.25g
- 200mg
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO
- 500mg
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA000GEW
- Product description1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide 99%
- Packaging100mg
- Price$114
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GEW
- Product description1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide 99%
- Packaging250mg
- Price$237
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GEW
- Product description1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide 99%
- Packaging25mg
- Price$41
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GEW
- Product description1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide ≥98%
- Packaging10mg
- Price$22
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GEW
- Product description1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide ≥98%
- Packaging5mg
- Price$12
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GEW
- Product description1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide 99%
- Packaging1mg
- Price$9
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-6563
- Product descriptionVX-661 98%
- Packaging100MG
- Price$80
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-6563
- Product descriptionVX-661 98%
- Packaging100MG
- Price$80
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-6563
- Product descriptionVX-661 98%
- Packaging1G
- Price$520
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-6563
- Product descriptionVX-661 98%
- Packaging1G
- Price$520
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0430
- Product description(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
- Packaging250mg
- Price$725
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0430
- Product description(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
- Packaging100mg
- Price$428
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2664
- Product descriptionVX-661
- Packaging50mg
- Price$440
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2664
- Product descriptionVX-661
- Packaging50mg
- Price$440
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2664
- Product descriptionVX-661
- Packaging10mM(in 1mL DMSO)
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2664
- Product descriptionVX-661
- Packaging10mM(in1mLDMSO)
- Price$115
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000GEW | 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide 99% | 100mg | $114 | 2026-05-25 | Buy |
| aablocks | AA000GEW | 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide 99% | 250mg | $237 | 2026-05-25 | Buy |
| aablocks | AA000GEW | 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide 99% | 25mg | $41 | 2026-05-25 | Buy |
| aablocks | AA000GEW | 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide ≥98% | 10mg | $22 | 2026-05-25 | Buy |
| aablocks | AA000GEW | 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide ≥98% | 5mg | $12 | 2026-05-25 | Buy |
| aablocks | AA000GEW | 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide 99% | 1mg | $9 | 2026-05-25 | Buy |
| ACHEMBLOCK | G-6563 | VX-661 98% | 100MG | $80 | 2026-05-27 | Buy |
| ACHEMBLOCK | G-6563 | VX-661 98% | 100MG | $80 | 2026-05-25 | Buy |
| ACHEMBLOCK | G-6563 | VX-661 98% | 1G | $520 | 2026-05-25 | Buy |
| ACHEMBLOCK | G-6563 | VX-661 98% | 1G | $520 | 2026-05-27 | Buy |
| AK Scientific | Y0430 | (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide | 250mg | $725 | 2021-12-16 | Buy |
| AK Scientific | Y0430 | (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide | 100mg | $428 | 2021-12-16 | Buy |
| ApexBio Technology | A2664 | VX-661 | 50mg | $440 | 2021-12-16 | Buy |
| ApexBio Technology | A2664 | VX-661 | 50mg | $440 | 2026-05-06 | Buy |
| ApexBio Technology | A2664 | VX-661 | 10mM(in 1mL DMSO) | $115 | 2021-12-16 | Buy |
| ApexBio Technology | A2664 | VX-661 | 10mM(in1mLDMSO) | $115 | 2026-05-06 | Buy |
Properties
Boiling point :610.8±55.0 °C(Predicted)
Density :1.49±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C , stored under nitrogen
solubility :≥21.8 mg/mL in DMSO; insoluble in EtOH; ≥24.3 mg/mL in H2O
form :solid
pka :13.99±0.20(Predicted)
color :White to yellow
InChIKey :MJUVRTYWUMPBTR-MRXNPFEDSA-N
SMILES :C1(C2=CC=C3OC(F)(F)OC3=C2)(C(NC2C(F)=CC3=C(C=2)C=C(C(C)(C)CO)N3C[C@@H](O)CO)=O)CC1
Density :1.49±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C , stored under nitrogen
solubility :≥21.8 mg/mL in DMSO; insoluble in EtOH; ≥24.3 mg/mL in H2O
form :solid
pka :13.99±0.20(Predicted)
color :White to yellow
InChIKey :MJUVRTYWUMPBTR-MRXNPFEDSA-N
SMILES :C1(C2=CC=C3OC(F)(F)OC3=C2)(C(NC2C(F)=CC3=C(C=2)C=C(C(C)(C)CO)N3C[C@@H](O)CO)=O)CC1
Safety Information
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Description
Tezacaftor (VX-661) is an oral medication for cystic fibrosis (CF) developed by Vertex Pharmaceuticals. In a combination therapy formulation called Symdeko (tezacaftor plus ivacaftor), it is approved in the U.S. and Canada for CF patients, ages 12 and older, who have two copies of the F508del mutation in the CFTR gene and one minimal function mutation. Symdeko is approved and marketed in the EU as Symkevi.Tezacaftor is not approved as a stand-alone treatment, but as part of a combination therapy.More related product prices
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Suppliers and manufacturers
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Tezacaftor
CAS:1152311-62-0
Qiuxian Baitai New Material Co., LTD
Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd.
Shandong Juntai Pharmaceutical Co. , Ltd.
Biochempartner
CONIER CHEM AND PHARMA LIMITED
ENBRIDGE PHARMTECH CO., LTD.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
VX-661
CAS:1152311-62-0