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ChemicalBook >> CAS DataBase List >> Trichloroacetic acid

Trichloroacetic acid

Trichloroacetic acid price.
  • $14 - $4601
  • Product name: Trichloroacetic acid
  • CAS: 76-03-9
  • MF: C2HCl3O2
  • MW: 163.39
  • EINECS:200-927-2
  • MDL Number:MFCD00004177
  • Synonyms:Deblock trichloroacetic acid solution;TRICHLOROACETIC ACID extrapure;RARECHEM AL BO 0072;Aceticacid,trichloro- ;Aceto-Caustin;Acide trichloracetique;acidetrichloracetique ;acidetrichloracetique(french)
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  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid 99%
  • Packaging100g
  • Price$29
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid
  • Packaging25g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid 99%
  • Packaging25g
  • Price$21
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid 99%
  • Packaging250g
  • Price$53
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid 99%
  • Packaging500g
  • Price$85
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid
  • Packaging1kg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid 99%
  • Packaging1kg
  • Price$131
  • Updated2026-06-04
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  • ManufacturerApolloscientific
  • Product numberOR8372
  • Product descriptionTrichloroacetic acid 99%
  • Packaging1kg
  • Price$130
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR8372
  • Product descriptionTrichloroacetic acid 99%
  • Packaging1kg
  • Price$130
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR8372
  • Product descriptionTrichloroacetic acid 99%
  • Packaging250g
  • Price$64
  • Updated2026-06-04
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  • ManufacturerApolloscientific
  • Product numberOR8372
  • Product descriptionTrichloroacetic acid 99%
  • Packaging250g
  • Price$64
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR8372
  • Product descriptionTrichloroacetic acid 99%
  • Packaging5kg
  • Price$626
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR8372
  • Product descriptionTrichloroacetic acid 99%
  • Packaging5kg
  • Price$626
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFT33532
  • Product descriptionTrichloroacetic acid
  • Packaging2kg
  • Price$649
  • Updated2026-06-04
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  • ManufacturerBiosynth
  • Product numberFT33532
  • Product descriptionTrichloroacetic acid
  • Packaging1kg
  • Price$389.4
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFT33532
  • Product descriptionTrichloroacetic acid
  • Packaging5kg
  • Price$1298
  • Updated2026-06-04
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Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific S221 Trichloroacetic acid 99% 100g $29 2026-06-04 Buy
AK Scientific S221 Trichloroacetic acid 25g $14 2021-12-16 Buy
AK Scientific S221 Trichloroacetic acid 99% 25g $21 2026-06-04 Buy
AK Scientific S221 Trichloroacetic acid 99% 250g $53 2026-06-04 Buy
AK Scientific S221 Trichloroacetic acid 99% 500g $85 2026-06-04 Buy
AK Scientific S221 Trichloroacetic acid 1kg $102 2021-12-16 Buy
AK Scientific S221 Trichloroacetic acid 99% 1kg $131 2026-06-04 Buy
Apolloscientific OR8372 Trichloroacetic acid 99% 1kg $130 2026-06-04 Buy
Apolloscientific OR8372 Trichloroacetic acid 99% 1kg $130 2026-06-04 Buy
Apolloscientific OR8372 Trichloroacetic acid 99% 250g $64 2026-06-04 Buy
Apolloscientific OR8372 Trichloroacetic acid 99% 250g $64 2026-06-04 Buy
Apolloscientific OR8372 Trichloroacetic acid 99% 5kg $626 2026-06-04 Buy
Apolloscientific OR8372 Trichloroacetic acid 99% 5kg $626 2026-06-04 Buy
Biosynth FT33532 Trichloroacetic acid 2kg $649 2026-06-04 Buy
Biosynth FT33532 Trichloroacetic acid 1kg $389.4 2026-06-04 Buy
Biosynth FT33532 Trichloroacetic acid 5kg $1298 2026-06-04 Buy

Properties

Melting point :54-58 °C (lit.)
Boiling point :196 °C (lit.)
bulk density :900kg/m3
Density :1.62 g/mL at 25 °C (lit.)
vapor density :<1 (vs air)
vapor pressure :1 mm Hg ( 51 °C)
refractive index :n20/D 1.62(lit.)
Flash point :196°C
storage temp. :Store at +15°C to +25°C.
solubility :H2O: 0.5 M at 20 °C, clear, colorless
form :Solid
pka :0.7(at 25℃)
color :White
PH :<1.0 (25℃, 0.5M in H2O)
Odor :sharp, pungent odor
Water Solubility :120 g/100 mL (20 ºC)
Sensitive :Hygroscopic
λmax :210nm(EtOH)(lit.)
Merck :14,9627
BRN :970119
Henry's Law Constant :7.3×102 mol/(m3Pa) at 25℃, Burkholder et al. (2019)
Dielectric constant :4.9(20℃)
Exposure limits :ACGIH: TWA 0.5 ppm
NIOSH: TWA 1 ppm(7 mg/m3) Stability :Stable, but moisture sensitive. Incompatible with water, strong bases. Note that the Merck Index states that this material is hydrolytically unstable in aqueous solution below 30% by weight. Decomposition products include carbon monoxide and carbon dioxide. The generation of these gases in a sealed container may lead to a pressure rise sufficien
InChI :1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChIKey :YNJBWRMUSHSURL-UHFFFAOYSA-N
SMILES :OC(=O)C(Cl)(Cl)Cl
LogP :1.330
CAS DataBase Reference :76-03-9(CAS DataBase Reference)
IARC :2B (Vol. 63, 84, 106) 2014
NIST Chemistry Reference :Acetic acid, trichloro-(76-03-9)
EPA Substance Registry System :Trichloroacetic acid (76-03-9)

Safety Information

Symbol(GHS): Corrosion (GHS05)Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning P234, P390, P404
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P234 Keep only in original container.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P363 Wash contaminated clothing before reuse.
P390 Absorb spillage to prevent material damage.
P391 Collect spillage. Hazardous to the aquatic environment
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.
P501 Dispose of contents/container to..…

Description

Trichloroacetic acid (TCA) is a kind of acetate analogue with the three hydrogen atoms of the methyl group in acetate being replaced by chlorine atoms. It is a strong acid which can be used in protein precipitation in clinical chemistry and biochemistry as well as a caustic for warts removal. It can be synthesize through the reaction between chlorine and acetate in the presence of a suitable catalyst, or alternatively by the oxidation of trichloroacetaldehyde. In addition to protein precipitation, it can also be used for RNA and DNA precipitation. Its sodium salt can also be used as a herbicide.

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