URB937
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- $33 - $1950
- Product name: URB937
- CAS: 1357160-72-5
- MF: C20H22N2O4
- MW: 354.4
- EINECS:604-604-1
- MDL Number:MFCD22987960
- Synonyms:URB937;Cyclohexylcarbamic acid 3′–carbamoyl–6–hydroxybiphenyl–3–yl ester;3'-Carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate;Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl ester;3'-Carbamoyl-6-hydroxy-[1,1'-biphenyl]-3-yl cyclohexylcarbamate;FAAH,URB 937,Inhibitor,URB937,low,toxicity,inhibit,Fatty acid amide hydrolase,OEA,URB-937;URB937, 10 mM in DMSO;URB937 ，S3586
53 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 003
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 100mg
- 100.00mg
- 250.00mg
- 250MG
- 1g
- Manufactureraablocks
- Product numberAA009BMA
- Product descriptionURB 937 ≥98%
- Packaging5mg
- Price$33
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009BMA
- Product descriptionURB 937 99%
- Packaging25mg
- Price$102
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009BMA
- Product descriptionURB 937 ≥98%
- Packaging10mg
- Price$59
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009BMA
- Product descriptionURB 937 99%
- Packaging100mg
- Price$290
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009BMA
- Product descriptionURB 937 99%
- Packaging50mg
- Price$171
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberK16293
- Product description3'-carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate 98%
- Packaging100MG
- Price$510
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberK16293
- Product description3'-carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate 98%
- Packaging250MG
- Price$940
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number7018DK
- Product description3'-Carbamoyl-6-hydroxybiphenyl-3-ylcyclohexylcarbamate
- Packaging100mg
- Price$704
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007729
- Product description3'-CARBAMOYL-6-HYDROXY-[1,1'-BIPHENYL]-3-YL CYCLOHEXYLCARBAMATE 98.00%
- Packaging5MG
- Price$496.99
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-116477
- Product descriptionURB937 99.62%
- Packaging100mg
- Price$504
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116477
- Product descriptionURB937 99.62%
- Packaging25mg
- Price$173
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116477
- Product descriptionURB937 99.62%
- Packaging50mg
- Price$295
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116477
- Product descriptionURB937 99.62%
- Packaging5mg
- Price$51
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116477
- Product descriptionURB937 99.62%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$53
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116477
- Product descriptionURB937 99.62%
- Packaging10mM*1mLinDMSO(Solution)
- Price$56
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-116477
- Product descriptionURB937 99.62%
- Packaging10mg
- Price$87
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009BMA | URB 937 ≥98% | 5mg | $33 | 2026-05-28 | Buy |
| aablocks | AA009BMA | URB 937 99% | 25mg | $102 | 2026-05-28 | Buy |
| aablocks | AA009BMA | URB 937 ≥98% | 10mg | $59 | 2026-05-28 | Buy |
| aablocks | AA009BMA | URB 937 99% | 100mg | $290 | 2026-05-28 | Buy |
| aablocks | AA009BMA | URB 937 99% | 50mg | $171 | 2026-05-28 | Buy |
| ACHEMBLOCK | K16293 | 3'-carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate 98% | 100MG | $510 | 2026-05-27 | Buy |
| ACHEMBLOCK | K16293 | 3'-carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate 98% | 250MG | $940 | 2026-05-27 | Buy |
| AK Scientific | 7018DK | 3'-Carbamoyl-6-hydroxybiphenyl-3-ylcyclohexylcarbamate | 100mg | $704 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007729 | 3'-CARBAMOYL-6-HYDROXY-[1,1'-BIPHENYL]-3-YL CYCLOHEXYLCARBAMATE 98.00% | 5MG | $496.99 | 2021-12-16 | Buy |
| Arctom | HY-116477 | URB937 99.62% | 100mg | $504 | 2026-05-26 | Buy |
| Arctom | HY-116477 | URB937 99.62% | 25mg | $173 | 2026-05-26 | Buy |
| Arctom | HY-116477 | URB937 99.62% | 50mg | $295 | 2026-05-26 | Buy |
| Arctom | HY-116477 | URB937 99.62% | 5mg | $51 | 2026-05-26 | Buy |
| Arctom | HY-116477 | URB937 99.62% | 10mM*1mLinDMSO(Solid+Solvent) | $53 | 2026-05-26 | Buy |
| Arctom | HY-116477 | URB937 99.62% | 10mM*1mLinDMSO(Solution) | $56 | 2026-05-26 | Buy |
| Arctom | HY-116477 | URB937 99.62% | 10mg | $87 | 2026-05-26 | Buy |
Properties
Boiling point :562.8±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :9.08±0.50(Predicted)
form :powder (1:1 ratio of product to ethanol)
color :white to beige
InChI :1S/C20H22N2O4/c21-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)23)26-20(25)22-15-7-2-1-3-8-15/h4-6,9-12,15,23H,1-3,7-8H2,(H2,21,24)(H,22,25)
InChIKey :CMEQHOXCIGFZNJ-UHFFFAOYSA-N
SMILES :N(C3CCCCC3)C(=O)Oc1cc(c(cc1)O)c2cc(ccc2)C(=O)N
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :9.08±0.50(Predicted)
form :powder (1:1 ratio of product to ethanol)
color :white to beige
InChI :1S/C20H22N2O4/c21-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)23)26-20(25)22-15-7-2-1-3-8-15/h4-6,9-12,15,23H,1-3,7-8H2,(H2,21,24)(H,22,25)
InChIKey :CMEQHOXCIGFZNJ-UHFFFAOYSA-N
SMILES :N(C3CCCCC3)C(=O)Oc1cc(c(cc1)O)c2cc(ccc2)C(=O)N
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
The enzyme fatty acid amide hydrolase (FAAH) is widely expressed in brain and other tissues, and is capable of hydrolyzing arachidonyl ethanolamide (AEA) and other simple esters and amides with long unsaturated acyl chains. URB937 is a potent fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 26.8 nM, in vitro) that does not penetrate the blood-brain barrier, thus preventing arachidonyl ethanolamide (AEA) deactivation only in peripheral tissues. Its ED50 value for FAAH inhibition in brain is 200-fold higher than the ED50 value for FAAH inhibition in liver when administered systemically in mice (40 mg/kg versus 0.2 mg/kg, respectively). Subcutaneous administration of URB937 reduces acetic acid-induced writhing in mice with an ED50 value of 0.1 mg/kg. A single 1 mg/kg injection of URB937 sufficiently attenuates behavioral responses elicited in mouse models of neuropathic and inflammatory pain. As a peripherally-specific FAAH inhibitor, URB937 may offer an alternative approach to pain therapy devoid of unwanted central effects.More related product prices
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