Vatalanib Dihydrochloride
|
- $9 - $2260
- Product name: Vatalanib Dihydrochloride
- CAS: 212141-51-0
- MF: C20H17Cl3N4
- MW: 419.74
- EINECS:
- MDL Number:MFCD08458964
- Synonyms:CGP-79787 Dihydrochlorid;N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Dihydrochloride;Vatalanib Dihydrochloride;CGP-79787 Dihydrochloride;Vatalanib 2hcl((ZK-222584,PTK 787);Vatalanib dihydrochloride (PTK787);CGP-79787;CGP-79787D
79 prices
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Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 5MG
- 10mM(in1mLDMSO)
- 1mg
- 10mg
- 20mg
- 25mg
- 50mg
- 50.00mg
- 100.00mg
- 100mg
- 200mg
- 250MG
- 250.00mg
- 500mg
- 1g
- 2g
- 5g
- Manufactureraablocks
- Product numberAA00BF2E
- Product descriptionVatalanib Dihydrochloride 99%(HPLC)
- Packaging1mg
- Price$9
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF2E
- Product descriptionVatalanib Dihydrochloride 99%(HPLC)
- Packaging10mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF2E
- Product descriptionVatalanib Dihydrochloride 99%(HPLC)
- Packaging50mg
- Price$43
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF2E
- Product descriptionVatalanib Dihydrochloride 99%(HPLC)
- Packaging100mg
- Price$57
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF2E
- Product descriptionVatalanib Dihydrochloride 98
- Packaging200mg
- Price$113
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF2E
- Product descriptionVatalanib Dihydrochloride 98%
- Packaging1g
- Price$396
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF2E
- Product descriptionVatalanib Dihydrochloride 98%
- Packaging5g
- Price$1342
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65745
- Product descriptionN-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride 98%
- Packaging1G
- Price$565
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65745
- Product descriptionN-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride 98%
- Packaging5G
- Price$2260
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65745
- Product descriptionN-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride 98%
- Packaging250MG
- Price$220
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number0818AB
- Product descriptionN-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-aminedihydrochloride
- Packaging50mg
- Price$157
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA392716
- Product descriptionVatalanib dihydrochloride 98+%
- Packaging50mg
- Price$214
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA392716
- Product descriptionVatalanib dihydrochloride 98+%
- Packaging100mg
- Price$278
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA392716
- Product descriptionVatalanib dihydrochloride 98+%
- Packaging250mg
- Price$417
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA392716
- Product descriptionVatalanib dihydrochloride 98+%
- Packaging1g
- Price$937
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000275
- Product descriptionVATALANIB HYDROCHLORIDE 95.00%
- Packaging5MG
- Price$550
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BF2E | Vatalanib Dihydrochloride 99%(HPLC) | 1mg | $9 | 2026-05-28 | Buy |
| aablocks | AA00BF2E | Vatalanib Dihydrochloride 99%(HPLC) | 10mg | $22 | 2026-05-28 | Buy |
| aablocks | AA00BF2E | Vatalanib Dihydrochloride 99%(HPLC) | 50mg | $43 | 2026-05-28 | Buy |
| aablocks | AA00BF2E | Vatalanib Dihydrochloride 99%(HPLC) | 100mg | $57 | 2026-05-28 | Buy |
| aablocks | AA00BF2E | Vatalanib Dihydrochloride 98 | 200mg | $113 | 2026-05-28 | Buy |
| aablocks | AA00BF2E | Vatalanib Dihydrochloride 98% | 1g | $396 | 2026-05-28 | Buy |
| aablocks | AA00BF2E | Vatalanib Dihydrochloride 98% | 5g | $1342 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65745 | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride 98% | 1G | $565 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65745 | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride 98% | 5G | $2260 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65745 | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride 98% | 250MG | $220 | 2026-05-27 | Buy |
| AK Scientific | 0818AB | N-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-aminedihydrochloride | 50mg | $157 | 2021-12-16 | Buy |
| Ambeed | A392716 | Vatalanib dihydrochloride 98+% | 50mg | $214 | 2021-12-16 | Buy |
| Ambeed | A392716 | Vatalanib dihydrochloride 98+% | 100mg | $278 | 2021-12-16 | Buy |
| Ambeed | A392716 | Vatalanib dihydrochloride 98+% | 250mg | $417 | 2021-12-16 | Buy |
| Ambeed | A392716 | Vatalanib dihydrochloride 98+% | 1g | $937 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000275 | VATALANIB HYDROCHLORIDE 95.00% | 5MG | $550 | 2021-12-16 | Buy |
Properties
Melting point :268-2700C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 20 mg/ml with warming) or in Water (up to 100 mg/ml)
form :solid
color :White or off-white
Water Solubility :H2O: 2mg/mL, clear
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
InChI :1S/C20H15ClN4.2ClH/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;;/h1-12H,13H2,(H,23,25);2*1H
InChIKey :AZUQEHCMDUSRLH-UHFFFAOYSA-N
SMILES :ClC(C=C1)=CC=C1NC2=NN=C(CC3=CC=NC=C3)C4=CC=CC=C42
CAS DataBase Reference :212141-51-0
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 20 mg/ml with warming) or in Water (up to 100 mg/ml)
form :solid
color :White or off-white
Water Solubility :H2O: 2mg/mL, clear
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
InChI :1S/C20H15ClN4.2ClH/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;;/h1-12H,13H2,(H,23,25);2*1H
InChIKey :AZUQEHCMDUSRLH-UHFFFAOYSA-N
SMILES :ClC(C=C1)=CC=C1NC2=NN=C(CC3=CC=NC=C3)C4=CC=CC=C42
CAS DataBase Reference :212141-51-0
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Vatalanib is an antagonist of the VEGF receptors, inhibiting the receptor tyrosine kinase activities of VEGFR1 (Flt1), VEGFR2 (KDR), and VEGFR3 (Flt4) with IC50 values of 77, 37, and 190 nM, respectively. It less potently inhibits PDGF and c-Kit (IC50 = 600 and 700 nM) and has no effect on a large panel of additional kinases. Vatalanib completely blocks retinal neovascularization in oxygen-induced ischemic retinopathy in mice, suggesting its use in diabetic retinopathy and other diseases featuring aberrant vascular development.Related product price
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