WEDELOLACTONE
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- $13 - $1720
- Product name: WEDELOLACTONE
- CAS: 524-12-9
- MF: C16H10O7
- MW: 314.25
- EINECS:200-158-5
- MDL Number:MFCD07778564
- Synonyms:1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one;6H-Benzofuro(3,2-C)(1)benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy-;5,11,12-Trihydroxy-7-MethoxycouMestan;1,8,9-trihydroxy-3-Methoxy-6H-benzofuro[3,2-c]chroMen-6-one;IKK Inhibitor II, Wedelolactone ;Wedelia lactone;Wedelolactone;Wedelolactone, ≥98%(HPLC)
78 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 500μg
- 20mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- y0001599
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1000mg
- 15 mg
- Manufactureraablocks
- Product numberAA00DA2A
- Product description1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98%
- Packaging1mg
- Price$13
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DA2A
- Product description1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98%
- Packaging5mg
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DA2A
- Product description1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98%
- Packaging10mg
- Price$35
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DA2A
- Product description1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98%
- Packaging50mg
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DA2A
- Product description1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98%
- Packaging100mg
- Price$99
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DA2A
- Product description1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98%
- Packaging250mg
- Price$222
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106050
- Product descriptionWedelolactone 98.00%
- Packaging50MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106050
- Product descriptionWedelolactone 98.00%
- Packaging100MG
- Price$120
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0424-M001
- Product descriptionWedelolactone ≥98%(HPLC)
- Packaging1mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0424-M005
- Product descriptionWedelolactone ≥98%(HPLC)
- Packaging5mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0424-M001
- Product descriptionWedelolactone ≥98%(HPLC)
- Packaging1mg
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000124
- Product descriptionWEDELOLACTONE 95.00%
- Packaging1MG
- Price$207.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2131
- Product descriptionWedelolactone
- Packaging20mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2131
- Product descriptionWedelolactone
- Packaging20mg
- Price$200
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-N0551R
- Product descriptionWedelolactone (Standard) 98%
- Packaging5mg
- Price$209
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N0551
- Product descriptionWedelolactone 99.87%
- Packaging10mg
- Price$179
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DA2A | 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98% | 1mg | $13 | 2026-05-28 | Buy |
| aablocks | AA00DA2A | 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98% | 5mg | $24 | 2026-05-28 | Buy |
| aablocks | AA00DA2A | 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98% | 10mg | $35 | 2026-05-28 | Buy |
| aablocks | AA00DA2A | 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98% | 50mg | $79 | 2026-05-28 | Buy |
| aablocks | AA00DA2A | 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98% | 100mg | $99 | 2026-05-28 | Buy |
| aablocks | AA00DA2A | 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one 98% | 250mg | $222 | 2026-05-28 | Buy |
| ACHEMBLOCK | U106050 | Wedelolactone 98.00% | 50MG | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | U106050 | Wedelolactone 98.00% | 100MG | $120 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CN2-0424-M001 | Wedelolactone ≥98%(HPLC) | 1mg | $70 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0424-M005 | Wedelolactone ≥98%(HPLC) | 5mg | $90 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0424-M001 | Wedelolactone ≥98%(HPLC) | 1mg | $30 | 2026-05-06 | Buy |
| American Custom Chemicals Corporation | INB0000124 | WEDELOLACTONE 95.00% | 1MG | $207.9 | 2021-12-16 | Buy |
| ApexBio Technology | N2131 | Wedelolactone | 20mg | $200 | 2021-12-16 | Buy |
| ApexBio Technology | N2131 | Wedelolactone | 20mg | $200 | 2026-05-06 | Buy |
| Arctom | HY-N0551R | Wedelolactone (Standard) 98% | 5mg | $209 | 2026-05-26 | Buy |
| Arctom | HY-N0551 | Wedelolactone 99.87% | 10mg | $179 | 2026-05-26 | Buy |
Properties
Melting point :327～330℃
Boiling point :498.4±45.0 °C(Predicted)
Density :1.655±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 14 mg/mL, soluble
form :solid
pka :6.90±0.20(Predicted)
color :brown-beige
InChI :InChI=1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
InChIKey :XQDCKJKKMFWXGB-UHFFFAOYSA-N
SMILES :C1(=O)OC2=CC(OC)=CC(O)=C2C2OC3=CC(O)=C(O)C=C3C1=2
Boiling point :498.4±45.0 °C(Predicted)
Density :1.655±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 14 mg/mL, soluble
form :solid
pka :6.90±0.20(Predicted)
color :brown-beige
InChI :InChI=1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
InChIKey :XQDCKJKKMFWXGB-UHFFFAOYSA-N
SMILES :C1(=O)OC2=CC(OC)=CC(O)=C2C2OC3=CC(O)=C(O)C=C3C1=2
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Wedelolactone is a natural coumestan originally isolated from plants used in herbal therapies. It inhibits NF-κB signaling at the level of IKK action, resulting in suppression of NF-κB-mediated gene expression at concentrations of 1-100 μM. Wedelolactone can also inhibit hepatitis C virus NS5B RNA-dependent RNA polymerase in vitro (IC50 = 36 μM), STAT1 dephosphorylation (50 μM), and EZH2-EED interactions (Kd = 2.8 μM). Prolonged incubation of HepG2 liver cells with wedelolactone alters lipid metabolism through increased expression of AMPK, PPARα, lipoprotein lipase, and low-density lipoprotein receptor.More related product prices
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Suppliers and manufacturers
Shanghai Standard Technology Co., Ltd.
Wedelolactone
CAS:524-12-9
Shaanxi Dideu Medichem Co. Ltd
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Nanjing Dolon Biotechnology Co.,Ltd.
TopScience Biochemical
CONIER CHEM AND PHARMA LIMITED
Wuhan ChemNorm Biotech Co.,Ltd.
Wedelolactone
CAS:524-12-9