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ChemicalBook >> CAS DataBase List >> WWL113

WWL113

WWL113 price.
  • $37 - $1253
  • Product name: WWL113
  • CAS: 947669-86-5
  • MF: C29H26N2O4
  • MW: 466.52774
  • EINECS:
  • MDL Number:MFCD28160857
  • Synonyms:WWL113;AKIIPHDGVCFVCC-UHFFFAOYSA-N;ethyl 4-[4-[methyl-[(3-pyridin-4-ylphenyl)methyl]carbamoyl]oxyphenyl]benzoate;4'-[[[Methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-[1,1'-biphenyl]-4-carboxylic acid ethyl ester;WWL-113,WWL113;[1,1'-Biphenyl]-4-carboxylic acid, 4'-[[[methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-, ethyl ester
40 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 10mM*1mLinDMSO(Solution)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 5 mg
  • 25 mg
  • Manufactureraablocks
  • Product numberAA01DNQD
  • Product descriptionWWL113 ≥98%
  • Packaging1mg
  • Price$41
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA01DNQD
  • Product descriptionWWL113 ≥98%
  • Packaging5mg
  • Price$99
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA01DNQD
  • Product descriptionWWL113
  • Packaging25mg
  • Price$331
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA01DNQD
  • Product descriptionWWL113
  • Packaging50mg
  • Price$533
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA01DNQD
  • Product descriptionWWL113 ≥98%
  • Packaging10mg
  • Price$178
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA01DNQD
  • Product descriptionWWL113
  • Packaging100mg
  • Price$889
  • Updated2026-05-29
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5248
  • Product descriptionWWL113
  • Packaging100mg
  • Price$925
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5248
  • Product descriptionWWL113
  • Packaging50mg
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-110148
  • Product descriptionWWL113 99.72%
  • Packaging25mg
  • Price$285
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-110148
  • Product descriptionWWL113 99.72%
  • Packaging10mg
  • Price$133
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-110148
  • Product descriptionWWL113 99.72%
  • Packaging50mg
  • Price$485
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-110148
  • Product descriptionWWL113 99.72%
  • Packaging100mg
  • Price$770
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-110148
  • Product descriptionWWL113 99.72%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$75
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-110148
  • Product descriptionWWL113 99.72%
  • Packaging5mg
  • Price$76
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-110148
  • Product descriptionWWL113 99.72%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$78
  • Updated2026-05-26
  • Buy
  • ManufacturerCayman Chemical
  • Product number16181
  • Product descriptionWWL113 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01DNQD WWL113 ≥98% 1mg $41 2026-05-29 Buy
aablocks AA01DNQD WWL113 ≥98% 5mg $99 2026-05-29 Buy
aablocks AA01DNQD WWL113 25mg $331 2026-05-29 Buy
aablocks AA01DNQD WWL113 50mg $533 2026-05-29 Buy
aablocks AA01DNQD WWL113 ≥98% 10mg $178 2026-05-29 Buy
aablocks AA01DNQD WWL113 100mg $889 2026-05-29 Buy
AK Scientific SYN5248 WWL113 100mg $925 2021-12-16 Buy
AK Scientific SYN5248 WWL113 50mg $560 2021-12-16 Buy
Arctom HY-110148 WWL113 99.72% 25mg $285 2026-05-26 Buy
Arctom HY-110148 WWL113 99.72% 10mg $133 2026-05-26 Buy
Arctom HY-110148 WWL113 99.72% 50mg $485 2026-05-26 Buy
Arctom HY-110148 WWL113 99.72% 100mg $770 2026-05-26 Buy
Arctom HY-110148 WWL113 99.72% 10mM*1mLinDMSO(Solid+Solvent) $75 2026-05-26 Buy
Arctom HY-110148 WWL113 99.72% 5mg $76 2026-05-26 Buy
Arctom HY-110148 WWL113 99.72% 10mM*1mLinDMSO(Solution) $78 2026-05-26 Buy
Cayman Chemical 16181 WWL113 ≥98% 1mg $37 2024-03-01 Buy

Properties

Boiling point :630.9±55.0 °C(Predicted)
Density :1+-.0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3 mg/ml; DMSO: 15 mg/ml; Ethanol: 0.1 mg/ml
form :A crystalline solid
pka :5.18±0.26(Predicted)
color :White to off-white
InChI :1S/C29H26N2O4/c1-3-34-28(32)25-9-7-22(8-10-25)23-11-13-27(14-12-23)35-29(33)31(2)20-21-5-4-6-26(19-21)24-15-17-30-18-16-24/h4-19H,3,20H2,1-2H3
InChIKey :AKIIPHDGVCFVCC-UHFFFAOYSA-N
SMILES :CCOC(C(C=C1)=CC=C1C(C=C2)=CC=C2OC(N(C)CC3=CC(C4=CC=NC=C4)=CC=C3)=O)=O

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Mouse carboxylesterase 3 (Ces3, also named Ces 1d) mediates triglyceride hydrolysis in white adipose tissue, liberating free fatty acids into circulation. Although important for basal lipolysis, Ces3 expression can be induced by xenobiotics. Ces3 activity is significantly elevated during adipocyte differentiation. WWL113 is a selective inhibitor of Ces3 and the structurally related Ces 1f (IC50 = ~0.1 μM) without significantly affecting several related enzymes. It significantly reduces basal lipolysis in adipocytes. More interestingly, WWL113 corrects multiple features of metabolic syndrome in obese-diabetic db/db mice, including changes in weight gain, glucose tolerance, and levels of nonesterified free fatty acids, triglycerides, total cholesterol, and fasted glucose. It has similar effects in mice with diet-induced obesity. WWL113 also inhibits the human ortholog of mouse Ces3, hCES1 (IC50 = ~50 nM), which has a similar tissue expression pattern to Ces3.

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