lubiprostone
|
- $39 - $4490
- Product name: lubiprostone
- CAS: 333963-40-9
- MF: C20H32F2O5
- MW: 390.46
- EINECS:1312995-182-4
- MDL Number:MFCD08444045
- Synonyms:(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid;Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11alpha,15R)-;Spi 0211;Unii-7662kg2R6k;(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-h;7-((1R,2R,3R)-2-(4,4-difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid;AMitiza Lubiprostone;7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid
38 prices
Selected condition：
Brand
- aablocks
- Alichem
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00C6UH
- Product description7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid 95%
- Packaging100mg
- Price$318
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C6UH
- Product description7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid 97%
- Packaging25mg
- Price$191
- Updated2026-05-28
- Buy
- ManufacturerAlichem
- Product number333963409
- Product description7-((2R,4AR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoicacid
- Packaging250mg
- Price$888.8
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number333963409
- Product description7-((2R,4AR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoicacid
- Packaging1g
- Price$1979.6
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005783
- Product descriptionLUBIPROSTONE-D4 95.00%
- Packaging5MG
- Price$496.11
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-B0680
- Product descriptionLubiprostone (hemiketal) 98.00%
- Packaging10mg
- Price$126
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-B0680
- Product descriptionLubiprostone (hemiketal) 98.00%
- Packaging100mg
- Price$629
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-B0680
- Product descriptionLubiprostone (hemiketal) 98.00%
- Packaging50mg
- Price$405
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-B0680
- Product descriptionLubiprostone (hemiketal) 98.00%
- Packaging25mg
- Price$252
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-B0680
- Product descriptionLubiprostone (hemiketal) 98.00%
- Packaging5mg
- Price$84
- Updated2026-05-26
- Buy
- ManufacturerAvaChem
- Product number2629
- Product descriptionLubiprostone
- Packaging25mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2629
- Product descriptionLubiprostone
- Packaging25mg
- Price$79
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number2629
- Product descriptionLubiprostone
- Packaging5mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2629
- Product descriptionLubiprostone
- Packaging5mg
- Price$39
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number2629
- Product descriptionLubiprostone
- Packaging10mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2629
- Product descriptionLubiprostone
- Packaging10mg
- Price$59
- Updated2026-05-22
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C6UH | 7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid 95% | 100mg | $318 | 2026-05-28 | Buy |
| aablocks | AA00C6UH | 7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid 97% | 25mg | $191 | 2026-05-28 | Buy |
| Alichem | 333963409 | 7-((2R,4AR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoicacid | 250mg | $888.8 | 2021-12-16 | Buy |
| Alichem | 333963409 | 7-((2R,4AR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoicacid | 1g | $1979.6 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005783 | LUBIPROSTONE-D4 95.00% | 5MG | $496.11 | 2021-12-16 | Buy |
| Arctom | HY-B0680 | Lubiprostone (hemiketal) 98.00% | 10mg | $126 | 2026-05-26 | Buy |
| Arctom | HY-B0680 | Lubiprostone (hemiketal) 98.00% | 100mg | $629 | 2026-05-26 | Buy |
| Arctom | HY-B0680 | Lubiprostone (hemiketal) 98.00% | 50mg | $405 | 2026-05-26 | Buy |
| Arctom | HY-B0680 | Lubiprostone (hemiketal) 98.00% | 25mg | $252 | 2026-05-26 | Buy |
| Arctom | HY-B0680 | Lubiprostone (hemiketal) 98.00% | 5mg | $84 | 2026-05-26 | Buy |
| AvaChem | 2629 | Lubiprostone | 25mg | $79 | 2021-12-16 | Buy |
| AvaChem | 2629 | Lubiprostone | 25mg | $79 | 2026-05-22 | Buy |
| AvaChem | 2629 | Lubiprostone | 5mg | $39 | 2021-12-16 | Buy |
| AvaChem | 2629 | Lubiprostone | 5mg | $39 | 2026-05-22 | Buy |
| AvaChem | 2629 | Lubiprostone | 10mg | $59 | 2021-12-16 | Buy |
| AvaChem | 2629 | Lubiprostone | 10mg | $59 | 2026-05-22 | Buy |
Properties
Boiling point :532.3±50.0 °C(Predicted)
Density :1.175
storage temp. :-20°C Freezer
pka :4.77±0.10(Predicted)
InChI :InChI=1/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/s3
InChIKey :WGFOBBZOWHGYQH-JSDKRCIBNA-N
SMILES :[C@@]12([H])CC(=O)[C@H](CCCCCCC(O)=O)[C@@]1([H])CC[C@@](C(F)(F)CCCC)(O)O2 |&1:0,5,15,19,r|
Density :1.175
storage temp. :-20°C Freezer
pka :4.77±0.10(Predicted)
InChI :InChI=1/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/s3
InChIKey :WGFOBBZOWHGYQH-JSDKRCIBNA-N
SMILES :[C@@]12([H])CC(=O)[C@H](CCCCCCC(O)=O)[C@@]1([H])CC[C@@](C(F)(F)CCCC)(O)O2 |&1:0,5,15,19,r|
Safety Information
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Description
Chronic constipation is an affliction affecting 4–5 million Americans alone. When no specific cause is identified, it is classified as idiopathic. Dietary and lifestyle modifications are the first-line conventional approaches followed by the administration of laxatives. Unfortunately, chronic idiopathic constipation is frequently refractory to traditional therapy; thus, the need for novel agents exists. Lubiprostone is a bicyclic fatty acid with a novel mechanism of action. Without affecting sodium and potassium ion concentrations, lubiprostone activates intestinal chloride ion channels, thereby, increasing intestinal water secretion and intestinal fluid chloride ion concentration. In basolateral membranepermeabilized T84 gastrointestinal epithelial cells under chloride gradient conditions, lubiprostone concentration-dependently increased short-circuit current with an EC50 of approximately 20 nM.Related product price
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Suppliers and manufacturers
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CONIER CHEM AND PHARMA LIMITED
Lubiprostone
CAS:333963-40-9
