15(S)-Fluprostenol isopropyl ester
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2物価
選択條件：
ブランド
- 富士フイルム和光純薬株式會社(wako)
パッケージ
- 0.5mg
- 5mg
- 生産者富士フイルム和光純薬株式會社(wako)
- 製品番號W01TRCT715605
- 製品説明
- 英語製品説明15-epi Travoprost
- 包裝単位0.5mg
- 価格￥112500
- 更新しました2018-12-26
- 購入
- 生産者富士フイルム和光純薬株式會社(wako)
- 製品番號W01TRCT715605
- 製品説明
- 英語製品説明15-epi Travoprost
- 包裝単位5mg
- 価格￥335500
- 更新しました2023-06-01
- 購入
| 生産者 | 製品番號 | 製品説明 | 包裝単位 | 価格 | 更新時間 | 購入 |
|---|---|---|---|---|---|---|
| 富士フイルム和光純薬株式會社(wako) | W01TRCT715605 | 15-epi Travoprost |
0.5mg | ￥112500 | 2018-12-26 | 購入 |
| 富士フイルム和光純薬株式會社(wako) | W01TRCT715605 | 15-epi Travoprost |
5mg | ￥335500 | 2023-06-01 | 購入 |
プロパティ
沸點 :584.8±50.0 °C(Predicted)
比重(密度) :1.245±0.06 g/cm3(Predicted)
溶解性 :DMF: 15 mg/ml; DMSO: 12 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml
酸解離定數(Pka) :13.43±0.20(Predicted)
外見 :Oil to Thick Oil
色 :Colourless
安定性： :Light Sensitive
比重(密度) :1.245±0.06 g/cm3(Predicted)
溶解性 :DMF: 15 mg/ml; DMSO: 12 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml
酸解離定數(Pka) :13.43±0.20(Predicted)
外見 :Oil to Thick Oil
色 :Colourless
安定性： :Light Sensitive
安全情報
| 絵表示(GHS): |
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| 注意喚起語: | Warning | ||||||||||||||
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説明
15(S)-Fluprostenol isopropyl ester (15(S)-Flu-Ipr) is the unnatural C-15 epimer of Travoprost. Travoprost is the Alcon trade name for fluprostenol isopropyl ester, (Flu-Ipr) an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Flu-Ipr is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid. The free acid, fluprostenol, is a potent FP receptor agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. Although data is currently not available for the activity of 15(S)-Flu-Ipr, inversion of the stereochemistry at the 15 position of ocular hypotensive prostaglandins generally lowers the potency approximately 100 fold.関連商品価格
- 5,6-trans Travoprost
￥120200-120200 - CIS-アトバコン
￥57900-448200 - トラボプロスト酸
￥17900-343200
供給者とメーカー
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