BOC-ASP(OME)-フルオロメチルケトン
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- ￥154000
- 化學名: BOC-ASP(OME)-フルオロメチルケトン
- 英語名: CASPASE INHIBITOR3
- 別名:BOC-ASP(OME)-フルオロメチルケトン
- CAS番號: 187389-53-3
- 分子式: C11H18FNO5
- 分子量: 263.26
- EINECS:
- MDL Number:MFCD07370667
1物価
選択條件：
ブランド
- Sigma-Aldrich Japan
パッケージ
- 3mg
- 生産者Sigma-Aldrich Japan
- 製品番號B2682
- 製品説明Boc-Asp(OMe)-フルオロメチルケトン ≥90% (TLC), solid
- 英語製品説明Boc-Asp(OMe)-fluoromethyl ketone ≥90% (TLC), solid
- 包裝単位3mg
- 価格￥154000
- 更新しました2024-03-01
- 購入
| 生産者 | 製品番號 | 製品説明 | 包裝単位 | 価格 | 更新時間 | 購入 |
|---|---|---|---|---|---|---|
| Sigma-Aldrich Japan | B2682 | Boc-Asp(OMe)-フルオロメチルケトン ≥90% (TLC), solid Boc-Asp(OMe)-fluoromethyl ketone ≥90% (TLC), solid |
3mg | ￥154000 | 2024-03-01 | 購入 |
プロパティ
沸點 :383.5±37.0 °C(Predicted)
比重(密度) :1.150±0.06 g/cm3 (20 ºC 760 Torr)
貯蔵溫度 :-20°C
溶解性 :Soluble in dry DMSO or DMF at approximately 20mM. Store stock solutions at -20°C.
酸解離定數(shù)(Pka) :10.12±0.46(Predicted)
外見 :Powder
色 :Off-white
InChI :InChI=1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)/t7-/m0/s1
InChIKey :MXOOUCRHWJYCAL-ZETCQYMHSA-N
SMILES :C(OC)(=O)C[C@H](NC(OC(C)(C)C)=O)C(=O)CF
比重(密度) :1.150±0.06 g/cm3 (20 ºC 760 Torr)
貯蔵溫度 :-20°C
溶解性 :Soluble in dry DMSO or DMF at approximately 20mM. Store stock solutions at -20°C.
酸解離定數(shù)(Pka) :10.12±0.46(Predicted)
外見 :Powder
色 :Off-white
InChI :InChI=1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)/t7-/m0/s1
InChIKey :MXOOUCRHWJYCAL-ZETCQYMHSA-N
SMILES :C(OC)(=O)C[C@H](NC(OC(C)(C)C)=O)C(=O)CF
安全情報
| 絵表示(GHS): |
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| 注意喚起語: | Warning | ||||||||||||||
| 危険有害性情報: |
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説明
Boc-D-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Also known as Boc-D(OMe)-FMK, this compound contains a methyl ester group, which facilitates uptake by cells and subsequently is removed by cytoplasmic esterases, leaving the functional inhibitor. Boc-D-FMK blocks apoptosis stimulated by TNF-α in neutrophils (IC50 = 39 μM), by bile duct ligation in hepatocytes, and by TNF-α in renal endothelial cells. The FMK pharmacophore is known to interact with non-caspase cysteine proteases, presumably explaining why Boc-D-FMK also inhibits cathepsins H and L.関連商品価格
- 銀アセチルアセトナート
￥18800-58600 - サルコミン
￥2900-145500 - ビス(2,4-ペンタンジオナト)銅(II)
￥2600-103420
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