| | 41307-63-5 Basic information More.. |
| Product Name: | Resorcinolnaphthalein | | Synonyms: | Resorcinolnaphthalein;FTUOFHGOGJGQAB-UHFFFAOYSA-N;fibrosis,ACE2,hypertension,renal,perivascular,Resorcinolnaphthalein,reversal,inhibit,myocardial,Inhibitor,Angiotensin-converting Enzyme (ACE);Spiro[1H,3H-naphtho[1,8-cd]pyran-1,9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-;Resorcinolnaphthalein, 10 mM in DMSO | | CAS: | 41307-63-5 | | MF: | C24H14O5 | | MW: | 382.36 | | EINECS: | | | Mol File: | 41307-63-5.mol |  |
Use
Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM). Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.[Cayman Chemical]
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41307-63-5
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