| | 68729-05-5 Basic information More.. |
| Product Name: | ARM1 | | Synonyms: | ARM1;4-(4-Benzylphenyl)-1,3-thiazol-2-amine;ARM-1
(ARM1);2-Thiazolamine, 4-[4-(phenylmethyl)phenyl]-;Epoxide Hydrolase,ARM1,HCT-116 cells,Inhibitor,LTA4H,ARM-1,cytotoxic,positive control,Aminopeptidase,4BSA,inhibit,ARM 1;2-Thiazolamine, 4-[4-(phenylmethyl)phenyl]- , ARM1;ARM1, 10 mM in DMSO | | CAS: | 68729-05-5 | | MF: | C16H14N2S | | MW: | 266.36 | | EINECS: | | | Mol File: | 68729-05-5.mol |  |
Use
Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 μM) and conversion of LTA4 to LTB4 by purified LTA4 hydrolase (Ki = 2.3 μM). ARM1 does not significantly affect the hydrolysis of Pro-Gly-Pro by LTA4 hydrolase.[Cayman Chemical]
- ARM1
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- $43.00
- 2026-04-22
- CAS:68729-05-5
- Purity: 99.36%
- Supply Ability: 10g
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68729-05-5
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