| | 110683-10-8 Basic information More.. |
| Product Name: | N-(p-amylcinnamoyl) Anthranilic Acid | | Synonyms: | N-(P-AMYLCINNAMOYL)ANTHRANILIC ACID;4-amylcinnamoylanthranilicacid;2-[[(E)-3-(4-PENTYLPHENYL)PROP-2-ENOYL]AMINO]BENZOIC ACID;N-(p-Amylcinnamoyl) anthranilic Acid (ACA);ACA;2-(3-(4-Pentylphenyl)acrylamido)benzoic acid;Benzoic acid, 2-[[1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]-;N(pamylcinnamoyl) Anthranilic Acid,Phospholipase,N (p amylcinnamoyl) Anthranilic Acid,inhibit,TRP Channel,Transient receptor potential channels,Inhibitor | | CAS: | 110683-10-8 | | MF: | C21H23NO3 | | MW: | 337.41 | | EINECS: | | | Mol File: | 110683-10-8.mol |  |
Use
N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 μM, respectively). It is a weak inhibitor of TRPV1. ACA is also an inhibitor of phospholipase A2, blocking the release of arachidonic acid when given at 50 μM.
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110683-10-8
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