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5011-34-7 Basic information More..
Product Name:Trimetazidine
Synonyms:ART-CHEM-BB B014361;ART-CHEM-BB B006602;AKOS B006602;1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;1-(2,3,4-TRIMETHOXY-BENZYL)-PIPERAZINE;TRIMETAZIDINE;TIMTEC-BB SBB007020;2,3-dimethoxy-4-(piperazinomethyl)phenyl methyl ether
CAS:5011-34-7
MF:C14H22N2O3
MW:266.34
EINECS:225-690-2
Mol File:5011-34-7.mol
5011-34-7

Use

Trimetazidine (TMZ) is a piperazine derivative. Its trade name is Vasorel. Its chemical name is 1(2, 3, 4trimethoxy benzyl) piperazine dihydrochloride. It is an anti angina drug. It has the effect of antagonizing adrenaline, norepinephrine and vasopressin. It can relax vascular smooth muscle directly, reduce vascular resistance, increase blood flow of coronary and peripheral circulation, promote myocardial metabolism and production of myocardial energy. At the same time, it can reduce the oxygen consumption of the myocardium, thereby improving the balance between supply and demand of heart muscle oxygen. It can increase the tolerance to cardiac glycosides, increase the tolerance to exercise test in patients with angina pectoris, reduce the frequency of angina pectoris, and reduce the dosage of nitroglycerin. It is used in the treatment of coronary insufficiency, angina pectoris and old myocardial infarction. It can be used in combination with digitalis in patients with severe heart failure.

Trimetazidine manufacturers

  • Trimetazidine
  • 2026-05-29
  • CAS:5011-34-7
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 1000KG
  • Trimetazidine
  • $1.00
  • 2019-12-25
  • CAS:5011-34-7
  • Min. Order: 1g
  • Purity: ≥98%
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