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Pharmaceutical Impurity Reference Standards

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Structure Chemical Name CAS MF
TiMolol IMpurity E TiMolol IMpurity E 1026075-53-5 C17H26N4O6S
EthanediaMide  iMpurity J EthanediaMide iMpurity J C2H4N2O2
4,6-dichloro-2-(propylthio)pyriMidine 4,6-dichloro-2-(propylthio)pyriMidine 1401318-10-2 C7H8Cl2N2S
Istradefylline impurity B Istradefylline impurity B
Ticagrelor diastereoMer Ticagrelor diastereoMer 1459719-81-3 C9H9F2N
Mirabegron iMpurity Mirabegron iMpurity 1581285-26-8 C16H21ClN2
Sunitinib iMpurity Sunitinib iMpurity 356068-98-9 C12H19N3O2
(-)-DihydroapovincaMinic Acid Ethyl Ester (-)-DihydroapovincaMinic Acid Ethyl Ester 57327-92-1 C22H28N2O2
(α1S,α4S,2S,5S)-2,5-DiMethyl-3,6-dioxo-α1,α4-bis(2-phenylethyl)-1,4-piperazinediacetic Acid 1,4-Diethyl Ester (α1S,α4S,2S,5S)-2,5-DiMethyl-3,6-dioxo-α1,α4-bis(2-phenylethyl)-1,4-piperazinediacetic Acid 1,4-Diethyl Ester 151387-05-2 C30H38N2O6
[2-(4-Fluorophenyl)cyclopropyl]aMine hydrochloride [2-(4-Fluorophenyl)cyclopropyl]aMine hydrochloride 879324-66-0 C9H11ClFN
[4-(4-AMino-7-hydroxy-6-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone [4-(4-AMino-7-hydroxy-6-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone 105356-90-9 C18H23N5O4
2-(DiethylaMino)-N-(2,5-diMethylphenyl)acetaMide Hydrochloride 2-(DiethylaMino)-N-(2,5-diMethylphenyl)acetaMide Hydrochloride 1012864-23-1 C14H23ClN2O
2-Keto-D-gulonic Acid Methyl Ester 2-Keto-D-gulonic Acid Methyl Ester 67776-07-2 C7H12O7
9,11-Dehydro-17α-cyanoMethyl Estradiol 9,11-Dehydro-17α-cyanoMethyl Estradiol 86153-38-0 C20H23NO2
DeMethyl Irbesartan DeMethyl Irbesartan 158778-58-6 C24H26N6O
Epiprednisolone Epiprednisolone 600-90-8 C21H28O5
δ-2-CefodiziMe (2 :1 Mixture) δ-2-CefodiziMe (2 :1 Mixture) 120533-30-4 C20H20N6O7S4
Salbutamol Acetonide Salbutamol Acetonide 54208-72-9 C16H25NO3
Tegafur Impurity BCB Tegafur Impurity BCB
((2R,3R,4R)-3-(benzoyloxy)-4-chloro-4-Methyl-5-oxotetrahydrofuran-2-yl)Methyl benzoate ((2R,3R,4R)-3-(benzoyloxy)-4-chloro-4-Methyl-5-oxotetrahydrofuran-2-yl)Methyl benzoate 1496551-65-5 C20H17ClO6
2-(4-fluorophenyl)-5-(2-Methylbenzyl)thiophene 2-(4-fluorophenyl)-5-(2-Methylbenzyl)thiophene 2005454-69-1 C18H15FS
AcetaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- AcetaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- 1429334-00-8 C16H19N3O5
PSI 7411 PSI 7411 1015073-43-4 C10H14FN2O8P
5-[[4-(Hydroxymethyl)phenoxy]methyl]-3-(1-methylethyl)-2-oxazolidinone 5-[[4-(Hydroxymethyl)phenoxy]methyl]-3-(1-methylethyl)-2-oxazolidinone 1071765-44-0 C14H19NO4
Ibrutinib Impurity 9 Ibrutinib Impurity 9 2068022-09-1 C25H21D5N6O4
4-CHLORO-3-HYDROXY BUTYRONITRILE 4-CHLORO-3-HYDROXY BUTYRONITRILE 105-33-9 C4H6ClNO
(Z)-2-propylhept-2-enal (Z)-2-propylhept-2-enal 95667-14-4 C10H18O
(R)-3-AMINO-4-(2,4-DIFLUOROPHENYL)-BUTYRIC ACID-HCL (R)-3-AMINO-4-(2,4-DIFLUOROPHENYL)-BUTYRIC ACID-HCL 1335470-16-0 C10H11F2NO2
(R)-2-((3-methyl-6-(3-((1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (R)-2-((3-methyl-6-(3-((1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile C23H25N7O4
(R)-2-((3-methyl-6-(3-((1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (R)-2-((3-methyl-6-(3-((1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile C23H25N7O4
4,4'-dichloro-3,3'-bis(4-ethoxybenzyl)-1,1'-biphenyl 4,4'-dichloro-3,3'-bis(4-ethoxybenzyl)-1,1'-biphenyl 2176485-21-3 C30H28Cl2O2
N-(2,6-dimethylphenyl)-2-((2,6-dimethylphenyl)amino)acetamide N-(2,6-dimethylphenyl)-2-((2,6-dimethylphenyl)amino)acetamide 294852-91-8 C18H22N2O
N6-propyl-3a,4,5,6,7,7a-hexahydrobenzo[d]thiazole-2,6-diamine N6-propyl-3a,4,5,6,7,7a-hexahydrobenzo[d]thiazole-2,6-diamine 1052691-22-1 C10H19N3S
3-pentylisoindolin-1-one 3-pentylisoindolin-1-one 691863-84-0 C13H17NO
(1R,3R)-2-acetyl-1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indole-3-carboxylate (1R,3R)-2-acetyl-1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indole-3-carboxylate 1598416-05-7 C22H20N2O5
8-Chloro-1-methyl-6-phenyl-4H-Imidazo[1,5-a][1,4]benzodiazepine 8-Chloro-1-methyl-6-phenyl-4H-Imidazo[1,5-a][1,4]benzodiazepine 59467-86-6 C18H14ClN3
BenzeneMethanaMine, 4-ethoxy-3-Methoxy-a-[(Methylsulfonyl)Methyl]- BenzeneMethanaMine, 4-ethoxy-3-Methoxy-a-[(Methylsulfonyl)Methyl]- 885268-06-4 C12H19NO4S
Afatinib IMpurity C Afatinib IMpurity C
Afatinib IMpurity C Afatinib IMpurity C
AMisulpride IMpurity AMisulpride IMpurity 84859-26-7 C8H17NO2
Avanafil iMpurity 5 Avanafil iMpurity 5
Cefoxitin iMpurity E (R-Methoxy cefoxitin) Cefoxitin iMpurity E (R-Methoxy cefoxitin)
Desloratadine IMpurity 3 Desloratadine IMpurity 3 1346600-61-0 C19H19ClN2
DibroMo IMpurity DibroMo IMpurity 1352492-08-0 C15H12Br2O2
ErtapeneM IMpurity DIPP ErtapeneM IMpurity DIPP 220031-86-7 C18H27N2O6PS
Gefitinib IMpurity 1 Gefitinib IMpurity 1 1561173-24-7 C15H22ClN3O3
Pitavastatin Defuoro IMpurity CalciuM Salt Pitavastatin Defuoro IMpurity CalciuM Salt 1258947-30-6 C50H50CaN2O8
Solifenacin Related CoMpound 4 Succinate Solifenacin Related CoMpound 4 Succinate 862207-71-4 C27H32N2O6
TenoxicaM IMpurity E (2-Methylthieno[2,3-d]isothiazol-3(2H)-one-1,1-dioxide ) TenoxicaM IMpurity E (2-Methylthieno[2,3-d]isothiazol-3(2H)-one-1,1-dioxide ) 94040-09-2 C6H5NO3S2
(+)-(14β)-Dihydrovinpocetine (+)-(14β)-Dihydrovinpocetine 57517-54-1 C22H28N2O2
D,L-Venlafaxine-d10 Hydrochloride D,L-Venlafaxine-d10 Hydrochloride 1216539-56-8 C17H28ClNO2
Ceritinib IMpurity Ceritinib IMpurity
Melphalan IMpurity Melphalan IMpurity
1-[2-[(5-chloro-2,4-diMethylphenyl)thio]phenyl]- Piperazine 1-[2-[(5-chloro-2,4-diMethylphenyl)thio]phenyl]- Piperazine 1240670-87-4 C18H21ClN2S
(1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol 2,3,4,6-tetrakis(2,2-dimethylpropanoate) (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol 2,3,4,6-tetrakis(2,2-dimethylpropanoate) 1283129-18-9 C44H57FO9S
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 2093243-16-2 C17H13NO4
Abacavir Impurity F Abacavir Impurity F 1443421-68-8 C18H26N6O
Lenvatinib Impurity 10 Lenvatinib Impurity 10
Nifuratel Impurity 10 Nifuratel Impurity 10
Ozagrel Impurity 16 Ozagrel Impurity 16 143945-86-2 C13H12N2O2
Tofacitinib Impurity 68 Tofacitinib Impurity 68
2-(4R,6S)(6-Formyl-2,2-dimethyl-[1,3]dioxan-4-yl)-acetic acid 2-(4R,6S)(6-Formyl-2,2-dimethyl-[1,3]dioxan-4-yl)-acetic acid 123185-91-1 C9H14O5
5-(3-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3- carbaldehyde 5-(3-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3- carbaldehyde C16H11FN2O3S
Dapoxetine impurity Dapoxetine impurity 126113-24-4 C19H16O2
Loratadine Impurity 17 Loratadine Impurity 17 133330-72-0 C14H12ClNO
Prasugrel Impurity 11 Prasugrel Impurity 11
someprazole Impurity 19 someprazole Impurity 19 358675-51-1 C16H17N3O3S
Trelagliptin Impurity 18 Trelagliptin Impurity 18
Ropivacaine impurity Ropivacaine impurity 1786560-34-6 C12H14N2O3
N-((3-(5-methyl-3-(4-(N-propionylsulfamoyl)phenyl)isoxazol-4-yl)phenyl)sulfonyl)propionamide N-((3-(5-methyl-3-(4-(N-propionylsulfamoyl)phenyl)isoxazol-4-yl)phenyl)sulfonyl)propionamide C22H23N3O7S2
LPHE-009 LPHE-009 64471-45-0 C13H16O3
2-((chloro(3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)-5- (difluoromethoxy)-1Na-benzo[d]imidazole 2-((chloro(3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)-5- (difluoromethoxy)-1Na-benzo[d]imidazole
(3S,3'S)-3,3'-((((4,4'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis (methylene))bis(4,1-phenylene))bis(oxy))bis(tetrahydrofuran) (3S,3'S)-3,3'-((((4,4'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis (methylene))bis(4,1-phenylene))bis(oxy))bis(tetrahydrofuran) C34H32Cl2O4
4-(1,3,2-Dioxaborinan-2-yl)benzonitrile 4-(1,3,2-Dioxaborinan-2-yl)benzonitrile 152846-62-3 C10H10BNO2
Rasagiline Impurity 5 Mesylate Rasagiline Impurity 5 Mesylate 1312077-04-5 C13H15NO4S
1-{[4-BENZYL-2-(3,4-DIMETHOXYPHENYL)-4H-CHROMEN-3-YL]METHYL}PIPERIDINIUM CHLORIDE 1-{[4-BENZYL-2-(3,4-DIMETHOXYPHENYL)-4H-CHROMEN-3-YL]METHYL}PIPERIDINIUM CHLORIDE C30H34ClNO3
4-Hydroxyisophthalonitrile 4-Hydroxyisophthalonitrile 34133-58-9 C8H4N2O
Empagliflozin Impurity 81 Empagliflozin Impurity 81
Iohexol Impurity M Iohexol Impurity M
Relugolix Impurity 18 Relugolix Impurity 18
Rabeprazole Impurity 15 Rabeprazole Impurity 15
4-((2-amino-2-oxoethyl)(hydroxy)amino)butanoic acid 4-((2-amino-2-oxoethyl)(hydroxy)amino)butanoic acid 2454698-45-2 C6H12N2O4
Lenvatinib Impurity LFZZ-8 Lenvatinib Impurity LFZZ-8 C44H40Cl2N8O8
Pemetrexed disodium Impurity 19 Pemetrexed disodium Impurity 19
Brivaracetam Impurity 32 Brivaracetam Impurity 32
1-((2R,3R)-3-(4-(aminomethyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-((2-(methylamino)acetoxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium chloride 1-((2R,3R)-3-(4-(aminomethyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-4-(1-((methyl(3-((2-(methylamino)acetoxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-4-ium chloride
Ticagrelor Impurity 107 Ticagrelor Impurity 107
2-Thiazolamine, 5-bromo-4-(5-bromo-4-chloro-2-thienyl)- 2-Thiazolamine, 5-bromo-4-(5-bromo-4-chloro-2-thienyl)- 2401867-89-6 C7H3Br2ClN2S2
Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-[2-[[4-(hydroxymethyl)benzoyl]methylamino]ethyl]-4-piperidinyl ester Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-[2-[[4-(hydroxymethyl)benzoyl]methylamino]ethyl]-4-piperidinyl ester 1682660-39-4 C29H33N3O4
sodium 3-(4-((1H-imidazol-1-yl)methyl)phenyl)-3-hydroxypropanoate sodium 3-(4-((1H-imidazol-1-yl)methyl)phenyl)-3-hydroxypropanoate
(4S,6R)-((4R,6S)-6-(2-(tert-butoxy)-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)methyl 6-(2-(tert-butoxy)-2-oxoethyl)-2,2-dimethyl-1,3-dioxane-4-carboxylate (4S,6R)-((4R,6S)-6-(2-(tert-butoxy)-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)methyl 6-(2-(tert-butoxy)-2-oxoethyl)-2,2-dimethyl-1,3-dioxane-4-carboxylate
tert-butyl 2-(((Z)-(1-(2-aminothiazol-4-yl)-2-(((2S,3S)-2-methyl-4- oxoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)-2-methyl propanoate tert-butyl 2-(((Z)-(1-(2-aminothiazol-4-yl)-2-(((2S,3S)-2-methyl-4- oxoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)-2-methyl propanoate
Atomoxetine Impurity 15 Atomoxetine Impurity 15 881995-45-5 C19H23NO2
Pitavastatin Impurity 13 (Pitavastatin 2,4,6-Triene Impurity) Pitavastatin Impurity 13 (Pitavastatin 2,4,6-Triene Impurity) 2086271-67-0 C25H20FNO2
(2S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2- carboxylic acid sodium (2S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2- carboxylic acid sodium
impurity 39 impurity 39
(2R,3R,4R,5S)-6-((2,4-dibromo-6-((cyclohexyl(methyl)amino)methyl)phenyl)amino)hexane-1,2,3,4,5-pentaol (2R,3R,4R,5S)-6-((2,4-dibromo-6-((cyclohexyl(methyl)amino)methyl)phenyl)amino)hexane-1,2,3,4,5-pentaol
Androsta-4,8(14)-dien-3-one, 17-hydroxy-, (17β)- (9CI) Androsta-4,8(14)-dien-3-one, 17-hydroxy-, (17β)- (9CI) 133177-83-0 C19H26O2
Bosutinib Impurity 32 Bosutinib Impurity 32
6,6'-Methylenebis[1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one 6,6'-Methylenebis[1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one 1365727-09-8 C29H26N2O2
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