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Pharmaceutical Impurity Reference Standards

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Structure Chemical Name CAS MF
Tofacitinib Impurity 116 Tofacitinib Impurity 116
Tofacitinib Impurity 121 Tofacitinib Impurity 121
Trelagliptin Impurity 28 Trelagliptin Impurity 28
Vildagliptin Impurity 31 Vildagliptin Impurity 31 119694-48-3 C10H14N4O6
Beclometasone Impurity M Beclometasone Impurity M
O-DESMETHYLCARVEDILOL O-DESMETHYLCARVEDILOL 72956-44-6 C23H24N2O4
Tolvaptan Impurity 7 Tolvaptan Impurity 7 1432725-23-9 C26H26N2O3
Dexchlorpheniramine impurity E Dexchlorpheniramine impurity E
Diquafosol Impurity F Diquafosol Impurity F
Dasatinib iMpurity F Dasatinib iMpurity F
Palbociclib Impurity 2 Palbociclib Impurity 2
Axitinib Impurity 6 Axitinib Impurity 6
Levofloxacin Impurity 16 Levofloxacin Impurity 16 C18H20FN3O4
Venlafaxine Impurity 13 Venlafaxine Impurity 13 727728-51-0 C17H27NO2
Erlotinib Impurity 20 Erlotinib Impurity 20
Febuxostat Impurity 42 Febuxostat Impurity 42
Pregabalin Impurity 11 Pregabalin Impurity 11 2375259-86-0 C8H16ClNO2
Ticagrelor Impurity 44 Ticagrelor Impurity 44
Exemestane Impurity 2 Exemestane Impurity 2
Empagliflozin Impurity 4 Empagliflozin Impurity 4
Moxifloxacin Impurity 14 Moxifloxacin Impurity 14
2-Benzothiazolamine 2-Benzothiazolamine
Cefodizime Impurity E Cefodizime Impurity E
Penicillin Impurity C Penicillin Impurity C
Cefminox Sodium impurity C Cefminox Sodium impurity C
Cefotiam Impurity C Cefotiam Impurity C
Dequalinium EP Impurity B Dequalinium EP Impurity B 747387-02-6 C30H40N4+2
Peramivir Impurity F Peramivir Impurity F
Lincomycin sulfoxide Impurity 4 Lincomycin sulfoxide Impurity 4
Sulpiride Impurity 3 Sulpiride Impurity 3
Doxofylline iMpurity F Doxofylline iMpurity F
He pulls non-EP impurities D He pulls non-EP impurities D
R-(-)-O-DESMETHYLVENLAFAXINE R-(-)-O-DESMETHYLVENLAFAXINE 142761-11-3 C16H25NO2
5-HYDROXY LANSOPRAZOLE 5-HYDROXY LANSOPRAZOLE 131926-98-2 C16H14F3N3O3S
(3S,5R)-4-[5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl]-4-oxobutanoic acid (3S,5R)-4-[5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl]-4-oxobutanoic acid C22H23NO4
Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-[4-(propan-2-yloxy)-4-oxobutanamido]-2-methylbutanoate Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-[4-(propan-2-yloxy)-4-oxobutanamido]-2-methylbutanoate C27H35NO5
Ticagrelor Impurity N Ticagrelor Impurity N 1643378-47-5 C23H29FN6O4S
carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester 929693-30-1 C14H26N2O4
Valaciclovir iMpurity Valaciclovir iMpurity
Erlotinib hydrochloride Impurity C Erlotinib hydrochloride Impurity C
Linagliptin Impurity B Linagliptin Impurity B
Parecoxib Impurity A Parecoxib Impurity A
Parecoxib Impurity F Parecoxib Impurity F
2-(4-Benzhydrylpiperazino)ethyl acetoacetate 2-(4-Benzhydrylpiperazino)ethyl acetoacetate 89226-49-3 C23H28N2O3
Axitinib Impurity a Axitinib Impurity a 1347304-18-0 C22H18N4O2S
Cycloocta[b]pyridine, 4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-2-(1-piperazinyl)- Cycloocta[b]pyridine, 4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-2-(1-piperazinyl)- 132811-84-8 C21H26FN3
Linagliptin Impurity W Linagliptin Impurity W
(R)-4-fluoro-2-((3-methyl-2,4-dioxo-6-(piperidin-3-ylamino)-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (R)-4-fluoro-2-((3-methyl-2,4-dioxo-6-(piperidin-3-ylamino)-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile C18H20FN5O2
1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid C21H24FN3O4
ethyl 1-cyclopropyl-7-fluoro-6,8-dimethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate ethyl 1-cyclopropyl-7-fluoro-6,8-dimethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate C17H18FNO5
Dapagliflozin Impurity 1 Dapagliflozin Impurity 1
Ibrutinib Impurity 5 Ibrutinib Impurity 5
Imatinib Impurity 4 Imatinib Impurity 4 942514-62-7 C30H33N7O
Macitentan Impurity 2 Macitentan Impurity 2 2211054-90-7 C10H8Br2N4O2
(R)-2-amino-4-(2-((4-(2-((2-hydroxy-2-phenylethyl)amino)ethyl) phenyl)amino)-2-oxoethyl)thiazole 3-oxide (R)-2-amino-4-(2-((4-(2-((2-hydroxy-2-phenylethyl)amino)ethyl) phenyl)amino)-2-oxoethyl)thiazole 3-oxide 1884646-38-1 C21H24N4O3S
Nilotinib Impurity 7 Nilotinib Impurity 7 2119583-26-3 C27H20F3N7O
Regorafenib Impurity 1 Regorafenib Impurity 1
Regorafenib Impurity 6 Regorafenib Impurity 6 1187945-05-6 C20H12ClF4N3O4
Sofosbuvir Impurity 9 Sofosbuvir Impurity 9
Venlafaxine N-Oxide Impurity Venlafaxine N-Oxide Impurity 1021933-95-8 C16H25NO3
Vonoprazan Impurity 4 Vonoprazan Impurity 4
Vortioxetine Impurity 25 Vortioxetine Impurity 25 1639263-80-1 C18H22N2O2S
Cinacalcet Impurity B Cinacalcet Impurity B 66469-40-7 C19H19N
Dapagliflozin Impurity D Dapagliflozin Impurity D 2133407-75-5 C21H25ClO6
Escitalopram Impurity Escitalopram Impurity 91283-87-3 C18H14FNO3
Furosemide Imp.(EP) Furosemide Imp.(EP)
Nifuratel Impurity Nifuratel Impurity 167103-07-3 C6H5N3O4
Vinpocetine Impurity Vinpocetine Impurity 102341-40-2 C19H23N3O
2-amino-9-((1R,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one 2-amino-9-((1R,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one 1367369-81-0 C12H15N5O3
N-(3,4-dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine N-(3,4-dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine 2089650-13-3 C22H24Cl2N4O3
Moxifloxacin Impurity 8 Moxifloxacin Impurity 8
(3R,5S)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid (3R,5S)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid C33H35FN2O5
Olaparib Imp.2 Olaparib Imp.2
Ciprofloxacin impurity I Ciprofloxacin impurity I C17H18FN3O3
5-(4'-((2-butyl-4-chloro-5-(isopropoxymethyl)-1H-imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole 5-(4'-((2-butyl-4-chloro-5-(isopropoxymethyl)-1H-imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole 1332713-64-0 C25H29ClN6O
Afatinib Impurity L (Afatinib N-Oxide) Afatinib Impurity L (Afatinib N-Oxide)
Afatinib Impurity L (Afatinib N-Oxide) Afatinib Impurity L (Afatinib N-Oxide)
Mirabegron Deshydroxy Mirabegron Deshydroxy 1581284-82-3 C21H24N4OS
4-Thiazoleacetyl chloride, 2-amino-, monohydrochloride 4-Thiazoleacetyl chloride, 2-amino-, monohydrochloride 66313-72-2 C5H6Cl2N2OS
1,2-bis(bromomethyl)-4,5-dimethoxybenzene 1,2-bis(bromomethyl)-4,5-dimethoxybenzene 26726-81-8 C10H12Br2O2
Alvimopan Impurity 2 Alvimopan Impurity 2
Alvimopan Impurity 4 Alvimopan Impurity 4
Isavuconazole Impurity 13 Isavuconazole Impurity 13
Sofosbuvir Impurity13 Sofosbuvir Impurity13 220503-64-0 C38H31N3O9
21-Acetyl-6β-fluorotriamcinolone Acetonide 21-Acetyl-6β-fluorotriamcinolone Acetonide 67438-37-3 C26H32F2O7
Quetiapine EP Impurity W Quetiapine EP Impurity W 1800608-95-0 C34H32N4O2S2
(2R,3R)-1,1,4,4-tetraphenylbutane-1,2,3,4-tetrol (2R,3R)-1,1,4,4-tetraphenylbutane-1,2,3,4-tetrol 117780-08-2 C28H26O4
(11β,16α)-21-(Acetyloxy)-11,16,17-trihydroxypregna-1,4,14-triene-3,20-dione (11β,16α)-21-(Acetyloxy)-11,16,17-trihydroxypregna-1,4,14-triene-3,20-dione 131918-72-4 C23H28O7
(S)-Alogliptin Benzoate Salt (S)-Alogliptin Benzoate Salt 1638544-64-5 C25H27N5O4
(S)-Alogliptin Benzoate Salt (S)-Alogliptin Benzoate Salt 1638544-64-5 C25H27N5O4
O-Acetyl Silodosin O-Acetyl Silodosin 160970-86-5 C27H34F3N3O5
Azilsartan Impurity Azilsartan Impurity 1675221-59-6 C25H22N2O5
Agomelatine Impurity 1 Agomelatine Impurity 1
Agomelatine Impurity 1 Agomelatine Impurity 1
Olaparib Impurity I Olaparib Impurity I
Brexpiprazole Impurity C Brexpiprazole Impurity C
Dapoxetine Impurity 7 Dapoxetine Impurity 7
Irbesartan Impurity 5 Irbesartan Impurity 5 1213252-81-3 C25H28N6O
Cabozantinib impurity C Cabozantinib impurity C
Loratadine Impurity 4 Loratadine Impurity 4 C22H23ClN2O2
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