Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI)

Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI) Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:BMH-22；BMH 22;BMH22
CAS:309726-06-5
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:BMH-22
CAS:309726-06-5
Package:25mg;1520USD|50mg;1980USD|100mg;2500USD
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
Products Intro: CAS:309726-06-5
Purity:98 Package:1G,5G,10G,50G,100G,500G
Company Name: Bide Pharmatech Ltd.  
Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Products Intro: Product Name:2,4,7,9-Tetramethylbenzo[b][1,8]naphthyridin-5-amine
CAS:309726-06-5
Purity:97% Package:25mg;50mg;100mg;250mg Remarks:BD177222
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310 15002144251
Email: marketing@tsbiochem.com
Products Intro: Product Name:BMH-22
CAS:309726-06-5
Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500

Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI) manufacturers

  • BMH-22
  • BMH-22 pictures
  • $1520.00
  • 2026-05-11
  • CAS:309726-06-5
  • Purity:
  • Supply Ability: 10g
Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI) Basic information
Product Name:Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI)
Synonyms:(2,4,7,9-tetramethylpyrido[2,3-b]quinolin-5-yl)amine;2,4,7,9-tetramethyl-5-pyrido[2,3-b]quinolinamine;2,4,7,9-tetramethylpyrido[2,3-b]quinolin-5-amine;Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI);BMH 22;BMH22;BMH-22
CAS:309726-06-5
MF:C16H17N3
MW:251.33
EINECS:
Product Categories:NAPHTHYRIDINE
Mol File:309726-06-5.mol
Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI) Structure
Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI) Chemical Properties
Safety Information
MSDS Information
Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI) Usage And Synthesis
DescriptionBMH-22 is an inhibitor of RNA polymerase I. It acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
UsesBMH-22, a benzonaphthyridin, is a RNA polymerase I (Pol I) transcription inhibitor independent of p53 function. BMH-22 causes reorganization of nucleolar marker proteins consistent with segregation of the nucleolus. BMH-22 destabilizes RPA194 in a proteasome-dependent manner and inhibits nascent rRNA synthesis and expression of the 45S rRNA precursor. BMH-22 shows potent anticancer activity across many tumor types[1].
References[1] RPA194, rRNA synthesis, 45S Rrna, anticancer Karita Peltonen, et al. Small molecule BMH-compounds that inhibit RNA polymerase I and cause nucleolar stress. Mol Cancer Ther. 2014 Nov;13(11):2537-46. DOI:10.1158/1535-7163.MCT-14-0256
Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI) Preparation Products And Raw materials
Tag:Benzo[b][1,8]naphthyridin-5-amine, 2,4,7,9-tetramethyl- (9CI)(309726-06-5) Related Product Information
5,7-DIMETHYL[1,8]NAPHTHYRIDIN-2-AMINE 4-AMINO-2,6-DIMETHYLQUINOLINE 4-AMINO-2,5,8-TRIMETHYLQUINOLINE 4-AMINO-2,8-DIMETHYLQUINOLINE 5,6,7-TRIMETHYL-1,8-NAPHTHYRIDIN-2-AMINE 2-Methyl-1,8-naphthyridin-4-aMine