| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:Apoptotic agent-2
CAS:2482310-18-7
Purity:大于98% Package:1g,5g,10g,25g根據(jù)客戶需要分裝 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Apoptotic agent-2
CAS:2482310-18-7
Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500
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11H-Indeno[1,2-b]quinoxalin-11-one, 2-[5-[2-(4-chlorophenyl)diazenyl]-4-methyl-2-thiazolyl]hydrazone manufacturers
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| | 11H-Indeno[1,2-b]quinoxalin-11-one, 2-[5-[2-(4-chlorophenyl)diazenyl]-4-methyl-2-thiazolyl]hydrazone Basic information |
| | 11H-Indeno[1,2-b]quinoxalin-11-one, 2-[5-[2-(4-chlorophenyl)diazenyl]-4-methyl-2-thiazolyl]hydrazone Chemical Properties |
| Boiling point | 808.7±75.0 °C(Predicted) | | density | 1.50±0.1 g/cm3(Predicted) | | pka | 6.26±0.20(Predicted) |
| | 11H-Indeno[1,2-b]quinoxalin-11-one, 2-[5-[2-(4-chlorophenyl)diazenyl]-4-methyl-2-thiazolyl]hydrazone Usage And Synthesis |
| Uses | Apoptotic agent-2 (compound 14b) induces apoptosis by down-regulation of Bcl-2 and up-regulation of Bax and caspase-3. Apoptotic agent-2 exhibits anti-proliferative activities and can be used for cancer research[1]. | | IC 50 | Bax; Caspase 3; Bcl-2 | | References | [1] Fayed EA, et al. In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies. Bioorg Chem. 2020 Jul;100:103951. DOI:10.1016/j.bioorg.2020.103951 |
| | 11H-Indeno[1,2-b]quinoxalin-11-one, 2-[5-[2-(4-chlorophenyl)diazenyl]-4-methyl-2-thiazolyl]hydrazone Preparation Products And Raw materials |
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