PARP7-IN-15

PARP7-IN-15 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:PARP7-IN-15
CAS:2819998-97-3
Package:50mg/RMB 24300
PARP7-IN-15 Basic information
Product Name:PARP7-IN-15
Synonyms:PARP7-IN-15;3(2H)-Pyridazinone, 5-[(2S)-2-[[3-oxo-3-[(6aS)-6a,7,9,10-tetrahydro-3-(trifluoromethyl)pyrazino[1,2-d]pyrido[3,2-b][1,4]oxazin-8(6H)-yl]propoxy]methyl]-1-azetidinyl]-4-(trifluoromethyl)-
CAS:2819998-97-3
MF:C23H24F6N6O4
MW:562.47
EINECS:
Product Categories:
Mol File:2819998-97-3.mol
PARP7-IN-15 Structure
PARP7-IN-15 Chemical Properties
density 1.646±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka9.080±0.60(predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
PARP7-IN-15 Usage And Synthesis
UsesPARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC50 of 0.56 nM, that has antitumor activity[1].
IC 50PARP7: 0.56 nM (IC50)
References[1] Silong Zhang , et al. Exploring the structural-activity relationship of hexahydropyrazino[1,2-d]pyrido[3,2-b][1,4]oxazine derivatives as potent and orally-bioavailable PARP7 inhibitors. Eur J Med Chem. 2023 Oct 8:261:115836. DOI:10.1016/j.ejmech.2023.115836
PARP7-IN-15 Preparation Products And Raw materials
Tag:PARP7-IN-15(2819998-97-3) Related Product Information