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| | FR901465 Basic information |
| Product Name: | FR901465 | | Synonyms: | FR901465;WB 2663C;2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-2,4-pentadien-1-yl]-2H-pyran-3-yl]-, (2Z,4S)-;DQTXAXNYLWRTPB-NTVXLVODSA-N;(2S,3Z)-4-{[(2R,3R,5S,6S)-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]penta-2,4-dien-1-yl]oxan-3-yl]carbamoyl}but-3-en-2-yl acetate | | CAS: | 146478-73-1 | | MF: | C27H41NO9 | | MW: | 523.62 | | EINECS: | | | Product Categories: | | | Mol File: | 146478-73-1.mol |  |
| | FR901465 Chemical Properties |
| Boiling point | 735.6±60.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | pka | 12.43±0.70(Predicted) |
| | FR901465 Usage And Synthesis |
| Uses | FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research[1]. | | Definition | ChEBI: A spiro-epoxide with potent cytotoxic activity against human tumour cells. It is isolated from Pseudomonas sp. no.2663. | | References | [1] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo). 1996 Dec;49(12):1204-11. DOI:10.7164/antibiotics.49.1204
[2] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465. J Antibiot (Tokyo). 1997 Jan;50(1):96-9. DOI:10.7164/antibiotics.50.96
[3] Ratnakar N. Asolkar, et al. Discovery and Development of Natural Products for Pest Management. RETURN TO BOOKPREVCHAPTERNEXT |
| | FR901465 Preparation Products And Raw materials |
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