| Company Name: |
Shanghai Xingui Biotechnology Co., Ltd.
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| Tel: |
15121041756 |
| Email: |
xingui2022@126.com |
| Products Intro: |
Product Name:(3R,4S,5S)-tert-butyl 4-(((benzyloxy)carbonyl)(methyl)amino)-3-methoxy-5-methylheptanoate
CAS:120205-58-5
Purity:95% Package:1g,5g,10g,25g
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| | PCUHBNWYHLQSBO-HQRMLTQVSA-N Basic information |
| Product Name: | PCUHBNWYHLQSBO-HQRMLTQVSA-N | | Synonyms: | PCUHBNWYHLQSBO-HQRMLTQVSA-N;(3R,4S,5S)-tert-butyl 4-(((benzyloxy)carbonyl)(methyl)amino)-3-methoxy-5-methylheptanoate;Monomethyl auristatin E intermediate-9 | | CAS: | 120205-58-5 | | MF: | C22H35NO5 | | MW: | 393.517 | | EINECS: | | | Product Categories: | | | Mol File: | 120205-58-5.mol |  |
| | PCUHBNWYHLQSBO-HQRMLTQVSA-N Chemical Properties |
| form | Oil | | color | Colorless to light yellow |
| | PCUHBNWYHLQSBO-HQRMLTQVSA-N Usage And Synthesis |
| Uses | Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1]. | | References | [1] Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87. DOI:10.1158/0008-5472.CAN-14-1931 |
| | PCUHBNWYHLQSBO-HQRMLTQVSA-N Preparation Products And Raw materials |
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