利托那韋EP雜質(zhì)O 基本信息
| 中文名稱 | 利托那韋EP雜質(zhì)O |
|---|---|
| 中文同義詞 | 利托那韋雜質(zhì)O (EP/BP);利托那韋EP雜質(zhì)O(BP雜質(zhì)O);利托那韋雜質(zhì)15;噻唑-5-基甲基((2S,3R,5S)-3-羥基-5-((S)-2-(3-((2-異丙基噻唑-4-基)甲基)-3-甲基脲基)-3- 甲基丁酰胺基)-1,6-二苯基己-2-基)氨基甲酸酯 (利托那韋雜質(zhì));利托那韋雜質(zhì)15(利托那韋EP雜質(zhì)O);4-表-利托那韋;化學(xué)試劑/4-EPI-RITONAVIR;利托那韋EP雜質(zhì)O |
| 英文名稱 | Ritonavir EP Impurity O |
| 英文同義詞 | Ritonavir Impurity 15(Ritonavir EP Impurity O);Ritonavir EP Impurity O(BP Impurity O);2,7,10,12-Tetraazatridecanoic acid, 4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3S,4R,6S,9S)-;Thiazol-5-ylmethyl((2S,3R,5S)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido;Ritonavir Impurity 15;Thiazol-5-ylmethyl [(1S,2R,4S)-1-benzyl-2-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl]amino]-5-phenylpentyl]carbamate;Thiazol-5-ylmethyl ((2S,3R,5S)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamido)-1,6-diphenylhexan-2-yl)carbamate (Ritonavir?Impurity);Ritonavir Intermediate 15 |
| CAS號(hào) | 1414933-81-5 |
| 分子式 | C37H48N6O5S2 |
| 分子量 | 720.94 |
| EINECS號(hào) | |
| 相關(guān)類別 | 雜質(zhì)對(duì)照品 |
| Mol文件 | 1414933-81-5.mol |
| 結(jié)構(gòu)式 |  |
利托那韋EP雜質(zhì)O 性質(zhì)
| 沸點(diǎn) | 947.0±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.239±0.06 g/cm3(Predicted) |
| 溶解度 | 可溶于氯仿（少許）、甲醇（少許） |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 11.47±0.46(Predicted) |
| 顏色 | 白色至類白色 |
| InChIKey | NCDNCNXCDXHOMX-RACJEYCXSA-N |
| SMILES | C(OCC1SC=NC=1)(=O)N[C@@H](CC1=CC=CC=C1)[C@H](O)C[C@H](CC1=CC=CC=C1)NC(=O)[C@H](C(C)C)NC(=O)N(C)CC1=CSC(C(C)C)=N1 |