腺苷5'-三磷酸二鈉鹽水合物
| 中文名稱 | 腺苷5'-三磷酸二鈉鹽水合物 |
|---|---|
| 中文同義詞 | 腺苷-5′-三磷酸二鈉鹽，（無鈣）;三磷酸腺苷二鈉鹽/ATP二鈉鹽;5-腺苷三磷酸二鈉鹽三水物;5-腺苷三磷酸二鈉鹽水合物;三磷酸腺苷二鈉鹽水合物;ATP二鈉鹽水合物;5'-三磷酸腺苷二鈉,磷酸腺苷鈉;5′-三磷酸腺苷 (ATP) 二鈉鹽 水合物 |
| 英文名稱 | ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& |
| 英文同義詞 | 5μ-ATP-Na2, ATP hydrate disodium salt;Adenosine-5'-triphosphate disodium salt hydrate, 99+% (water <10%);Adenosine 5'-triphosphate, disodium salt hydrate,98%;Adenosine-5'-triphosphate disodium salt hydrate, water <10%;Adenosine 5′-triphosphate disodium salt hydrate,5′-ATP-Na2, ATP disodium salt hydrate;Adenosine 5′-triphosphate disodium salt hydrate,ATP disodium salt;Adenosine 5'-triphosphate disodiuM salt hydrate 99%;Adenosine 5'-(tetrahydrogen triphosphate) disodium salt hydrate |
| CAS號 | 34369-07-8 |
| 分子式 | C10H19N5NaO14P3 |
| 分子量 | 549.19 |
| EINECS號 | 213-579-1 |
| 相關(guān)類別 | 小分子抑制劑，天然產(chǎn)物;雜環(huán);植物激素及核酸類;醫(yī)藥原料藥;含硫化合物;小分子抑制劑;生化試劑;腺苷;核苷，核苷酸，寡核苷酸;Inhibitors;生化試劑-植物激素及核酸類;化工原料;Pharmaceutical;中間體-有機(jī)中間體;通用生化試劑-核酸;化學(xué)試劑;食品添加劑 |
| Mol文件 | 34369-07-8.mol |
| 結(jié)構(gòu)式 |  |
腺苷5'-三磷酸二鈉鹽水合物 性質(zhì)
| 熔點(diǎn) | 176 °C (dec.)(lit.) |
|---|---|
| 儲存條件 | -20°C |
| 溶解度 | 在水中的溶解度為50mg/mL，透明，無色 |
| 形態(tài) | 粉末 |
| 酸度系數(shù)(pKa) | (1) 4.0, (2) 6.5 |
| 顏色 | 白色 |
| 生物來源 | microbial (Corynebacterium sp.) |
| 水溶解性 | Soluble in water. |
| 最大波長(λmax) | 259 nm |
| 敏感性 | Light Sensitive & Hygroscopic |
| Merck | 14,155 |
| BRN | 3585462 |
| 穩(wěn)定性 | 吸濕性、溫度敏感 |
| InChIKey | NTBQNWBHIXNPRU-MSQVLRTGSA-L |
| SMILES | [Na+].[Na+].[H]O[H].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O |
| CAS 數(shù)據(jù)庫 | 34369-07-8 |
ATP disodium salt hydrate (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP disodium salt hydrate (2 mM; 0.5-24 hours) induces secretion of interleukin 1β, KC and MIP-2 from bone marrow derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.
ATP disodium salt hydrate stimulats cytokine and chemokine secretion and inflammasome activation directly and indirectly induces in vitro neutrophil chemotaxis.
ATP disodium salt hydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium salt hydrate induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo.
| Animal Model: | Four-week-old Kunming mice (18-22 g) |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal injection, before bacterial ( E. coli ) challenge |
| Result: | Protected mice from bacterial infection. |
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2026/07/06 | L14522 | 腺苷-5'-三磷酸二鈉鹽水合物, 99%, water <10% Adenosine-5'-triphosphate disodium salt hydrate, 99%, water <10% | 34369-07-8 | 1g | 461元 |
| 2026/07/06 | J10585 | 腺苷-5′-三磷酸二鈉鹽，（無鈣） Adenosine-5'-triphosphate disodium salt hydrateThermo Scientific | 34369-07-8 | 100g | 3171元 |