| Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
|
| Tel: |
+86-156-80926068 +86-15680926068 |
| Email: |
1924344760@qq.com |
| Products Intro: |
Product Name:N-Mal-N-bis(PEG4-amine) TFA salt CAS:2128735-22-6 Purity:95% HPLC Package:10MG;25MG;50MG;100MG;1G;5G
|
N-Mal-N-bis(PEG4-amine) TFA salt manufacturers
|
| | N-Mal-N-bis(PEG4-amine) TFA salt Basic information |
| | N-Mal-N-bis(PEG4-amine) TFA salt Chemical Properties |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| | N-Mal-N-bis(PEG4-amine) TFA salt Usage And Synthesis |
| Description | N-Mal-N-bis(PEG4-amine) TFA salt is a branched PEG linker with a terminal maleimide group and two terminal amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. | | Uses | N-Mal-N-bis(PEG4-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-Mal-N-bis(PEG4-amine) TFA salt Preparation Products And Raw materials |
|