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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:trans-Resveratrol 3-O-β-D-Glucuronide
CAS:387372-17-0
Package:10Mg,1Mg
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| | trans Resveratrol 3-O-β-D-Glucuronide Basic information |
| | trans Resveratrol 3-O-β-D-Glucuronide Chemical Properties |
| Melting point | >150C (dec.) | | Boiling point | 758.065±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.616±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | -20°C Freezer, Under Inert Atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 2.787±0.70(predicted) | | color | Off-White to Pale Beige | | biological source | synthetic | | Stability: | Hygroscopic |
| | trans Resveratrol 3-O-β-D-Glucuronide Usage And Synthesis |
| Description | Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. In humans, resveratrol is almost completely conjugated to its glucuronide and sulfate metabolites. trans-Resveratrol-3-O-β-D-glucuronide is a regioisomeric resveratrol metabolite that may be used as a reference standard for accurate determination of the metabolic profile of resveratrol. | | Chemical Properties | Off-White Solid | | Uses | A metabolite of trans Resveratrol (R150000). | | Uses | Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. In humans, resveratrol is almost completely conjugated to its glucuronide and sulfate metabolites. trans-Resveratrol-3-O-β-D-glucuronide is a regioisomeric resveratrol metabolite that may be used as a reference standard for accurate determination of the metabolic profile of resveratrol. | | Definition | ChEBI: Trans-Resveratrol 3-O-glucuronide is a stilbenoid and a glycoside. | | References | [1] G A POTTER. The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1[J]. British Journal of Cancer, 2002, 86 5: 774-778. DOI: 10.1038/sj.bjc.6600197
[2] VIRGINIE AUMONT . Regioselective and Stereospecific Glucuronidation of trans- and cis-Resveratrol in Human[J]. Archives of biochemistry and biophysics, 2001, 393 2: Pages 281-289. DOI: 10.1006/abbi.2001.2496
[3] BARBARA CALAMINI. Pleiotropic mechanisms facilitated by resveratrol and its metabolites.[J]. Biochemical Journal, 2010, 429 2: 273-282. DOI: 10.1042/bj20091857
[4] ELENA POLYCARPOU. Resveratrol 3-O-d-glucuronide and resveratrol 4′-O-d-glucuronide inhibit colon cancer cell growth: Evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest[J]. Molecular Nutrition & Food Research, 2013, 57 10: 1708-1717. DOI: 10.1002/mnfr.201200742
[5] MELLINA S. SIMES . Resveratrol biotransformation and actions on the liver metabolism of healthy and arthritic rats[J]. Life sciences, 2022, 310: Article 120991. DOI: 10.1016/j.lfs.2022.120991 |
| | trans Resveratrol 3-O-β-D-Glucuronide Preparation Products And Raw materials |
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