| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Sugiol
CAS:511-05-7
Purity:98.5% Package:5mg Remarks:BBP02645
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(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one manufacturers
- Sugiol
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- $668.00
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2026-07-27
- CAS:511-05-7
- Purity:
- Supply Ability: 10g
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| | (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one Basic information |
| Product Name: | (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one | | Synonyms: | (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one;(+)-Sugiol;(4aS)-2,3,4,4a,10,10aα-Hexahydro-6-hydroxy-1,1,4a-trimethyl-7-isopropylphenanthren-9(1H)-one;12-Hydroxyabieta-8,11,13-triene-7-one;10-Deoxoxanthoperol;9(1H)-Phenanthrenone, 2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)-;Sugiol | | CAS: | 511-05-7 | | MF: | C20H28O2 | | MW: | 300.44 | | EINECS: | | | Product Categories: | | | Mol File: | 511-05-7.mol |  |
| | (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one Chemical Properties |
| Melting point | 290-292 °C (decomp) | | Boiling point | 185-205 °C(Press: 0.1 Torr) | | density | 1.049±0.06 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 8.71±0.60(Predicted) | | color | White to off-white | | LogP | 6.770 (est) |
| | (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one Usage And Synthesis |
| Uses | Sugiol is an abietane diterpenoid, can be isolated from Calocedrus formosana bark. Sugiol has anti-inflammatory activity, could effectively reduce intracellular reactive oxygen species (ROS) production in lipopolysaccharide (LPS)-stimulated macrophages[1]. | | Definition | ChEBI: Sugiol is an abietane diterpenoid that is ferruginol in which the methylene group para to the phenolic hydroxy group has been substituted by an oxo group. It has a role as a plant metabolite, an antiviral agent, an antineoplastic agent, an antioxidant and a radical scavenger. It is an abietane diterpenoid, a carbotricyclic compound, a meroterpenoid, a member of phenols and a cyclic terpene ketone. It is functionally related to a ferruginol. | | Cytotoxicity | IC50 (μg/mL): <50 (SW620, HCT116,MDA-MB-231, NCI-H23, and A549)(Son et al. 2005)
IC50 (μg/mL): >30.04 (MRC-5, PC-3),23.98 (A549), 20.62 (Hl-60), 26.4(PANC-1), 10.82 (BxPC-3) (Li et al.2013). | | target | ROS | IL Receptor | TNF-α | MAPK | ERK | JNK | p38MAPK | | IC 50 | ERK1; ERK2; p38 MAPK; JNK1; JNK2; IL-1β | | References | [1] Chao KP, et al. Anti-inflammatory activity of sugiol, a diterpene isolated from Calocedrus formosana bark. Planta Med. 2005 Apr;71(4):300-5. DOI:10.1055/s-2005-864094 |
| | (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one Preparation Products And Raw materials |
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