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| | DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE Basic information |
| Product Name: | DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE | | Synonyms: | DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE;3-(N,N-Dimethylaminomethyl)phenylboronic acid, pinacol ester;3-Dimethylaminomethylphenylboronic acid pinacol ester;Dimethyl[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]amine;3-Dimethylaminomethylphenylboronic acid pinacol ester
Dimethyl[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]amine;N,N-dimethyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine;N,N-Dimethyl-1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methylamine;Dimethyl({[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl})amine | | CAS: | 909391-56-6 | | MF: | C15H24BNO2 | | MW: | 261.17 | | EINECS: | | | Product Categories: | | | Mol File: | 909391-56-6.mol | ![DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE Structure](CAS/GIF/909391-56-6.gif) |
| | DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE Chemical Properties |
| Boiling point | 340.8±25.0 °C(Predicted) | | density | 1.00 | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 8.78±0.28(Predicted) | | Appearance | Colorless to off-white Solid-Liquid Mixture |
| | DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE Usage And Synthesis |
| Synthesis | Step X1 Intermediate XI.1: 2-(3-(bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (297 mg, 1.0 mmol) was dissolved in acetonitrile (5 mL), a methanol solution of dimethylamine (2 M, 1.0 mL, 2.0 mmol) was added followed by potassium carbonate (691 mg, 5.0 mmol). The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, acetonitrile was removed under vacuum and the residue was partitioned with ethyl acetate and water. The organic layer was washed with saturated sodium bicarbonate solution, dried over magnesium sulfate, filtered and the filtrate was concentrated to afford dimethyl-[3-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzyl]amine (Intermediate XI.1) as a viscous oily substance (200 mg, 0.77 mmol, 77% yield). Characterization data for intermediate XI.1: 1H NMR (300 MHz, CD3OD): δ 7.70 (m, 2H), 7.30-7.45 (m, 2H), 3.50 (s, 2H), 2.28 (s, 6H), 1.36 (s, 12H) ppm; MS (ESI), m/z: 262 ([M + H]+). | | References | [1] Patent: WO2006/95014, 2006, A1. Location in patent: Page/Page column 43-44 |
| | DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE Preparation Products And Raw materials |
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