| Company Name: |
Shanghai Topbiochem Technology Co., Ltd
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| Tel: |
+86-21-60341587 |
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sales@topbiochem.com |
| Products Intro: |
Product Name:4-(Pyridin-3-yloxy)benzoicacid
CAS:437383-99-8
Purity:98% Package:1g;5g;25g;100g;500g;1kg
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| Company Name: |
SynAsst Chemical.
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| Tel: |
021-60343070 |
| Email: |
|
| Products Intro: |
Product Name:4-(Pyridin-3-yloxy)benzoic acid
CAS:437383-99-8
Purity:96%Min Package:10g 100g 500g
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| | 4-(PYRIDIN-3-YLOXY)BENZOIC ACID Basic information |
| | 4-(PYRIDIN-3-YLOXY)BENZOIC ACID Chemical Properties |
| Boiling point | 391.2±22.0 °C(Predicted) | | density | 1.298±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | pka | 3.98±0.10(Predicted) | | Appearance | White to off-white Solid |
| | 4-(PYRIDIN-3-YLOXY)BENZOIC ACID Usage And Synthesis |
| Synthesis | Step 2. Synthesis of 4-(pyridin-3-yloxy)benzoic acid. Methyl 4-(pyridin-3-yloxy)benzoate (0.8 g) was dissolved in methanol (10 mL) and aqueous sodium hydroxide solution (2 mL) was added. The reaction mixture was stirred at 75°C for 1 hour. Upon completion of the reaction, it was neutralized with 1N hydrochloric acid (10 mL) and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to afford 4-(pyridin-3-yloxy)benzoic acid (0.8 g, 93% yield) as a white solid. LC-MS analysis showed the molecular ion peak of the target compound m/z: 215 ([M+H]+). | | References | [1] Patent: WO2014/176258, 2014, A1. Location in patent: Page/Page column 37 |
| | 4-(PYRIDIN-3-YLOXY)BENZOIC ACID Preparation Products And Raw materials |
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