Posaconazole-d4

Posaconazole-d4 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Posaconazole-D4；SCH 56592-D4
CAS:1133712-26-1
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Nextpeptide Inc
Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Products Intro: Product Name:Posaconazole D4
CAS:1133712-26-1
Purity:98% Min. Package:5KG;1KG
Company Name: SIMSON PHARMA LIMITED
Tel: +91-8291074273
Email: k.das@simsonpharma.com
Products Intro: Product Name:Posaconazole-D4
CAS:1133712-26-1
Purity:96% Package:5mg;USD|10mg;USD|25mg;USD
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:Posaconazole-D4
CAS:1133712-26-1
Package:5mg;|1mg;283.00;USD
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:Posaconazole-d4
CAS:1133712-26-1
Purity:>=97% Package:$902.9/1mg;Bulk package Remarks:97%

Posaconazole-d4 manufacturers

  • Posaconazole-D4
  • Posaconazole-D4 pictures
  • 2023-05-27
  • CAS:1133712-26-1
  • Min. Order: 1mg
  • Purity: 96%
  • Supply Ability: 50 mg
Posaconazole-d4 Basic information
Product Name:Posaconazole-d4
Synonyms:Posaconazole-d4;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol-d4;Noxafil-d4;Sch 56592-d4;2-[(2S,3S)-2-hydroxypentan-3-yl]-4-[2,3,5,6-tetradeuterio-4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one;Posacozole-d5;[2H4]-Posaconazole;POSACONAZOLE (D4, 98%) 1.0 MG/ML IN METHANOL
CAS:1133712-26-1
MF:C37H42F2N8O4
MW:700.79
EINECS:
Product Categories:Chiral Reagents;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
Mol File:1133712-26-1.mol
Posaconazole-d4 Structure
Posaconazole-d4 Chemical Properties
Melting point 170-172C
storage temp. -20°C Freezer
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
form Solid
color Off-White to Light Grey
Stability:Moisture Sensitive
InChIKeyRAGOYPUPXAKGKH-YWOVKAAPSA-N
SMILESFC1=CC(F)=CC=C1[C@]2(CN3C=NC=N3)OC[C@@H](COC4=CC=C(N5CCN(C6=C([2H])C([2H])=C(N7C=NN([C@@H](CC)[C@@H](O)C)C7=O)C([2H])=C6[2H])CC5)C=C4)C2
Safety Information
WGK Germany WGK 2
Storage Class3 - Flammable liquids
Hazard ClassificationsAcute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1
MSDS Information
Posaconazole-d4 Usage And Synthesis
Chemical PropertiesOff-White Foam
UsesOrally active labelled triazole antifungal.
ApplicationPosaconazole-d4, an isotope of posaconazole, was used as an internal standard and showed retention and ionization identical to those of posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
General DescriptionThis stable-labeled internal standard is suitable for quantification of posaconazole levels in blood, serum, or plasma by HPLC or LC-MS/MS. The antifungal posaconazole is used to treat invasive and systemic fungal infections. As a result of significant drug interactions, therapeutic drug monitoring of posaconazole is recommended when administered with protease inhibitors (PIs) or non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Liquid chromatography-mass spectrometry method for the quantification of posaconazole in human plasma: Application to pharmacokinetics following single-dose administration in the fasted state and with a high-fat meal
Posaconazole-d4 Preparation Products And Raw materials
Tag:Posaconazole-d4(1133712-26-1) Related Product Information
Posaconazole Impurity 49 Posaconazole Impurity 44 Posaconazole Impurity 17 Posaconazole 1-((2S,3R)-2-(benzyloxy)pentan-3-yl)-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide Posaconazole Diastereoisomer 11 Posaconazole DiastereoisoMer interMediate 5 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Posaconazole DiastereoisoMer 2 Posaconazole inter-8 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one Posaconazole iMpurity D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- 1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]- Posaconazole Diastereoisomer 12 Posaconazole DiastereoisoMer interMediate 2 1H-1,2,4-TRIAZOLE, 1-[[(2S)-2-(2,4-DIFLUOROPHENYL)OXIRANYL]METHYL]- Posaconazole-d5