| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:3,4-DiMethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylMethyl)-2-thiazolyl]-benzenesulfonaMide
CAS:1008119-83-2
Package:50Mg,5Mg
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| Company Name: |
ChemCell Biomedicine Co.,Ltd.
|
| Tel: |
020-13556033878 2965585218 13556033878 |
| Email: |
chemcell@hotmail.com |
| Products Intro: |
Product Name:3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide
CAS:1008119-83-2
Purity:98% Package:1Mg;5Mg;10Mg;50Mg;100Mg;250Mg;500Mg;1g;5g;10g
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:JM-6
CAS:1008119-83-2
Purity:>98 % Remarks:Reach out to us for more information about custom solutions.
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3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide manufacturers
- JM6
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- $2500.00
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2026-05-11
- CAS:1008119-83-2
- Purity:
- Supply Ability: 10g
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| | 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide Basic information |
| Product Name: | 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide | | Synonyms: | JM 6 (enzyme inhibitor);3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide;JM 6;2-(3,4-Dimethoxybenzenesulfonylamino)-4-(3-nitrophenyl)-5-(piperidin-1-yl)methylthiazole;3,4-dimethoxy-N-[4-(3-nitrophenyl)-5-(piperidin-1-ylmethyl)-1,3-thiazol-2-yl]benzenesulfonamide;JM6
(KMO inhibitor JM6);Benzenesulfonamide, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide | | CAS: | 1008119-83-2 | | MF: | C23H26N4O6S2 | | MW: | 518.61 | | EINECS: | | | Product Categories: | | | Mol File: | 1008119-83-2.mol |  |
| | 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide Chemical Properties |
| Boiling point | 692.2±65.0 °C(Predicted) | | density | 1.391±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble2mg/mL (clear solution, warmed) | | pka | 5.90±0.10(Predicted) | | form | powder | | color | white to beige | | InChIKey | AOZLMMDVJOGGEQ-UHFFFAOYSA-N | | SMILES | COc1ccc(cc1OC)S(=O)(=O)Nc2nc(c(CN3CCCCC3)s2)-c4cccc(c4)[N+]([O-])=O |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide Usage And Synthesis |
| Uses | 3,4-dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide is also known as JM6. Studies have shown JM6 participates in the inhibitory effects towards kynurenine 3-monooxygenase in its activities in blood ameliorates neurodegeneration. | | Biological Activity | JM6 is a prodrug inhibitor of kynurenine 3-monooxygenase (KMO) th at increases kynurenic acid levels and reduces extracellular glutamate in the brain. JM6 prevents spatial memory deficits, anxiety-related behavior, and synaptic loss in mouse model of Alzheimer disease. |
| | 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide Preparation Products And Raw materials |
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