Bromoacetamido-PEG2-Acid manufacturers
- BrCH2CONH-PEG2-acid
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2025-06-07
- CAS:1415800-44-0
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Bromoacetamido-PEG2-Acid Basic information |
| Product Name: | Bromoacetamido-PEG2-Acid | | Synonyms: | Bromoacetamido-PEG2-Acid;CAS_1415800-44-0;Bromoacetamido-PEG2-CH2CH2COOH;Bromoacetamido-PEG2-C2-acid;3-(2-(2-(2-Bromoacetamido)ethoxy)ethoxy)propanoic acid;Bromoacetamido-PEG2-CH2CH2COOH/Propanoic acid, 3-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]-;Propanoic acid, 3-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]- | | CAS: | 1415800-44-0 | | MF: | C9H16BrNO5 | | MW: | 298.13 | | EINECS: | | | Product Categories: | | | Mol File: | 1415800-44-0.mol |  |
| | Bromoacetamido-PEG2-Acid Chemical Properties |
| Boiling point | 491.4±45.0 °C(Predicted) | | density | 1.464±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | pka | 4.28±0.10(Predicted) | | form | Solid-Liquid Mixture | | color | White to yellow |
| | Bromoacetamido-PEG2-Acid Usage And Synthesis |
| Description | Bromoacetamido-PEG2-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | Uses | Bromoacetamido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bromoacetamido-PEG2-Acid Preparation Products And Raw materials |
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